Epigenome-wide analysis across the development span of pediatric acute lymphoblastic leukemia: backtracking to birth.

Autor: Ghantous A; Epigenomics and Mechanisms Branch, International Agency for Research on Cancer, (IARC), 25 avenue Tony Garnier, CS 90627, Lyon, Cedex 07 69366, France. GhantousA@iarc.who.int., Nusslé SG; Genknowme SA, Alanine Building, Corniche Road 5, 1066, Epalinges, Switzerland., Nassar FJ; Epigenomics and Mechanisms Branch, International Agency for Research on Cancer, (IARC), 25 avenue Tony Garnier, CS 90627, Lyon, Cedex 07 69366, France., Spitz N; Epigenomics and Mechanisms Branch, International Agency for Research on Cancer, (IARC), 25 avenue Tony Garnier, CS 90627, Lyon, Cedex 07 69366, France., Novoloaca A; Epigenomics and Mechanisms Branch, International Agency for Research on Cancer, (IARC), 25 avenue Tony Garnier, CS 90627, Lyon, Cedex 07 69366, France., Krali O; Department of Medical Sciences, Molecular Precision Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Nickels E; Center for Genetic Epidemiology, University of Southern California, Los Angeles, USA.; Cancer and Blood Disease Institute, Children's Hospital Los Angeles, Los Angeles, USA., Cahais V; Epigenomics and Mechanisms Branch, International Agency for Research on Cancer, (IARC), 25 avenue Tony Garnier, CS 90627, Lyon, Cedex 07 69366, France., Cuenin C; Epigenomics and Mechanisms Branch, International Agency for Research on Cancer, (IARC), 25 avenue Tony Garnier, CS 90627, Lyon, Cedex 07 69366, France., Roy R; Computational Biology and Informatics Core, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, USA., Li S; Center for Genetic Epidemiology, University of Southern California, Los Angeles, USA., Caron M; Department of Pediatrics, University of Montreal & Research Center, Centre Hospitalier Universitaire (CHU) Sainte-Justine, Montréal, Quebec, Canada., Lam D; School of Molecular Sciences, The University of Western Australia, Crawley, Western Australia, 6009, Australia.; Harry Perkins Institute of Medical Research, Nedlands, Western Australia, 6009, Australia., Fransquet PD; Centre for Social and Early Emotional Development (SEED), School of Psychology, Deakin University, Burwood, Victoria, Australia., Casement J; Bioinformatics Support Unit, Newcastle University, Newcastle upon Tyne, UK., Strathdee G; Newcastle University Centre for Cancer, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK., Pearce MS; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Hansen HM; Neuro and Molecular Epidemiology Laboratory, University of California San Francisco, San Francisco, USA., Lee HH; Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, 10408, Korea., Lee YS; Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, 10408, Korea., de Smith AJ; Center for Genetic Epidemiology, University of Southern California, Los Angeles, USA., Sinnett D; Department of Pediatrics, University of Montreal & Research Center, Centre Hospitalier Universitaire (CHU) Sainte-Justine, Montréal, Quebec, Canada., Håberg SE; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway., McKay JA; Department of Applied Sciences, Northumbria University, Newcastle upon Tyne, UK., Nordlund J; Department of Medical Sciences, Molecular Precision Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Magnus P; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway., Dwyer T; Clinical Sciences Theme, Heart Group, Murdoch Children's Research Institute, Melbourne, Australia.; Nuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, UK.; Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Australia., Saffery R; Murdoch Children's Research Institute and Department of Paediatrics, University of Melbourne, Melbourne, Australia., Wiemels JL; Center for Genetic Epidemiology, University of Southern California, Los Angeles, USA., Munthe-Kaas MC; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.; Department of Pediatric Oncology and Hematology, Oslo University Hospital, Oslo, Norway., Herceg Z; Epigenomics and Mechanisms Branch, International Agency for Research on Cancer, (IARC), 25 avenue Tony Garnier, CS 90627, Lyon, Cedex 07 69366, France. HercegZ@iarc.who.int.

Publikováno v: Molecular cancer [Mol Cancer] 2024 Oct 23; Vol. 23 (1), pp. 238. Date of Electronic Publication: 2024 Oct 23.

Epigenetic age acceleration and the risk of frailty, and persistent activities of daily living (ADL) disability.

Autor: Phyo AZZ; Biological Neuropsychiatry & Dementia Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia., Espinoza SE; Center for Translational Geroscience, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Murray AM; Berman Center for Outcomes and Clinical Research, Hennepin HealthCare Research Institute, Minneapolis, MN, USA.; Division of Geriatrics, Department of Medicine, Hennepin HealthCare and University of Minnesota, Minneapolis, MN, USA., Fransquet PD; Biological Neuropsychiatry & Dementia Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.; School of Psychology, Deakin University, Burwood, Melbourne, VIC 3125, Australia., Wrigglesworth J; Biological Neuropsychiatry & Dementia Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia., Woods RL; ASPREE Research Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia., Ryan J; Biological Neuropsychiatry & Dementia Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.

Publikováno v: Age and ageing [Age Ageing] 2024 Jun 01; Vol. 53 (6).

Exploring perinatal biopsychosocial factors and epigenetic age in 1-year-old offspring.

Autor: Fransquet PD; Deakin University, Centre for Social & Early Emotional Development, School of Psychology, Faculty of Health, Geelong, Victoria, Australia., Macdonald JA; Deakin University, Centre for Social & Early Emotional Development, School of Psychology, Faculty of Health, Geelong, Victoria, Australia.; Murdoch Children's Research Institute, Population Studies of Adolescents, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia.; The University of Melbourne, Department of Paediatrics, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia., Ryan J; School of Public Health & Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia., Greenwood CJ; Deakin University, Centre for Social & Early Emotional Development, School of Psychology, Faculty of Health, Geelong, Victoria, Australia.; Murdoch Children's Research Institute, Population Studies of Adolescents, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia.; The University of Melbourne, Department of Paediatrics, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia., Olsson CA; Deakin University, Centre for Social & Early Emotional Development, School of Psychology, Faculty of Health, Geelong, Victoria, Australia.; Murdoch Children's Research Institute, Population Studies of Adolescents, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia.; The University of Melbourne, Department of Paediatrics, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia.

Publikováno v: Epigenomics [Epigenomics] 2023 Sep; Vol. 15 (18), pp. 927-939. Date of Electronic Publication: 2023 Oct 31.

Accelerated Epigenetic Aging in Peripheral Blood does not Predict Dementia Risk.

Autor: Fransquet PD; School of Public Health and Preventive Medicine, Monash University, Melbourne, 3004, Victoria, Australia., Lacaze P; School of Public Health and Preventive Medicine, Monash University, Melbourne, 3004, Victoria, Australia., Saffery R; Murdoch Children's Research Institute, Department of Paediatrics, The University of Melbourne, Parkville, 3052 Victoria, Australia., Shah RC; Department of Family Medicine and Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL 60612, United States., Vryer R; Murdoch Children's Research Institute, Department of Paediatrics, The University of Melbourne, Parkville, 3052 Victoria, Australia., Murray A; Berman Center for Outcomes and Clinical Research, Hennepin Healthcare Research Institute, Hennepin Healthcare, Division of Geriatrics, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, United States., Woods RL; School of Public Health and Preventive Medicine, Monash University, Melbourne, 3004, Victoria, Australia., Ryan J; School of Public Health and Preventive Medicine, Monash University, Melbourne, 3004, Victoria, Australia.

Publikováno v: Current Alzheimer research [Curr Alzheimer Res] 2021; Vol. 18 (5), pp. 443-451.

Blood DNA methylation signatures to detect dementia prior to overt clinical symptoms.

Autor: Fransquet PD; School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia., Lacaze P; School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia., Saffery R; Department of Paediatrics Murdoch Children's Research Institute The University of Melbourne Parkville Victoria Australia., Phung J; School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia., Parker E; School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia., Shah R; Department of Family Medicine and Rush Alzheimer's Disease Center Rush University Medical Center Chicago Illinois USA., Murray A; Berman Center for Outcomes and Clinical Research Hennepin Healthcare, Division of Geriatrics Department of Medicine Hennepin Healthcare Research Institute University of Minnesota Minneapolis Minnesota USA., Woods RL; School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia., Ryan J; School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia.; PSNREC Université de Montpellier INSERM Montpellier France.

Publikováno v: Alzheimer's & dementia (Amsterdam, Netherlands) [Alzheimers Dement (Amst)] 2020 Jul 09; Vol. 12 (1), pp. e12056. Date of Electronic Publication: 2020 Jul 09 (Print Publication: 2020).