Amyloid burden quantification depends on PET and MR image processing methodology.

Autor: Guilherme D Kolinger, David Vállez García, Antoon T M Willemsen, Fransje E Reesink, Bauke M de Jong, Rudi A J O Dierckx, Peter P De Deyn, Ronald Boellaard

Publikováno v: PLoS ONE, Vol 16, Iss 3, p e0248122 (2021)

Quantification of amyloid load with positron emission tomography can be useful to assess Alzheimer's Disease in-vivo. However, quantification can be affected by the image processing methodology applied. This study's goal was to address how amyloid qu

Externí odkaz: https://doaj.org/article/19713534b05a4f1f8019a18914968653

Relative cerebral flow from dynamic PIB scans as an alternative for FDG scans in Alzheimer's disease PET studies.

Autor: Débora E Peretti, David Vállez García, Fransje E Reesink, Tim van der Goot, Peter P De Deyn, Bauke M de Jong, Rudi A J O Dierckx, Ronald Boellaard

Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0211000 (2019)

In Alzheimer's Disease (AD) dual-tracer positron emission tomography (PET) studies with 2-[18F]-fluoro-2-deoxy-D-glucose (FDG) and 11C-labelled Pittsburgh Compound B (PIB) are used to assess metabolism and cerebral amyloid-β deposition, respectively

Externí odkaz: https://doaj.org/article/cc27b1122dbe45f6b224dfe94668021f

The impact of tau-PET in a selected memory clinic cohort: rationale and design of the TAP-TAU study

Autor: Marie R. Vermeiren, Joost Somsen, Gert Luurtsema, Fransje E. Reesink, Nicolaas A. Verwey, Liesbeth Hempenius, Nelleke Tolboom, Geert Jan Biessels, J. Matthijs Biesbroek, Meike W. Vernooij, Sophie E. M. Veldhuijzen van Zanten, Harro Seelaar, Emma M. Coomans, Charlotte E. Teunissen, Afina W. Lemstra, Argonde C. van Harten, Leonie N. C. Visser, Wiesje M. van der Flier, Elsmarieke van de Giessen, Rik Ossenkoppele

Publikováno v: Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)

Abstract Background Tau-PET is a diagnostic tool with high sensitivity and specificity for discriminating Alzheimer’s disease (AD) dementia from other neurodegenerative disorders in well-controlled research environments. The role of tau-PET in real

Externí odkaz: https://doaj.org/article/d3a59bc2cf6d4922a76611eb0bd5f947

Serum and cerebrospinal fluid neutrophil gelatinase-associated lipocalin (NGAL) levels as biomarkers for the conversion from mild cognitive impairment to Alzheimer's disease dementia

Autor: Peter Paul De Deyn, Ulrich L. M. Eisel, Petrus J.W. Naudé, Inez H.G.B. Ramakers, Fransje E. Reesink, Wiesje M. van der Flier, Lize C. Jiskoot, Huiberdina L Koek, Jurgen A H R Claassen

Publikováno v: Naudé, P J W, Ramakers, I H G B, van der Flier, W M, Jiskoot, L C, Reesink, F E, Claassen, J A H R, Koek, H L, Eisel, U L M & de Deyn, P P 2021, ' Serum and cerebrospinal fluid Neutrophil gelatinase-associated lipocalin (NGAL) levels as biomarkers for the conversion from mild cognitive impairment to Alzheimer's disease dementia ', Neurobiology of Aging, vol. 107, pp. 1-10 . https://doi.org/10.1016/j.neurobiolaging.2021.07.001
Neurobiology of Aging, 107, 1-10. Elsevier Inc.
Neurobiology of aging
Neurobiology of Aging, 107, pp. 1-10
Neurobiology of Aging, 107, 1-10
Neurobiology of Aging, 107, 1-10. ELSEVIER SCIENCE INC
Neurobiology of Aging, 107, 1-10. Elsevier Science

Neutrophil gelatinase-associated lipocalin (NGAL) is an acute phase protein that has been reported as a potential marker for pre-dementia stages of Alzheimer's disease (AD). Longitudinal studies for its association with the conversion of mild cogniti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3449aaa52169cfa7cbf5aeff97956f2
https://doi.org/10.1016/j.neurobiolaging.2021.07.001

FDG-PET combined with learning vector quantization allows classification of neurodegenerative diseases and reveals the trajectory of idiopathic REM sleep behavior disorder

Autor: Rick van Veen, Sanne K. Meles, Remco J. Renken, Fransje E. Reesink, Wolfgang H. Oertel, Annette Janzen, Gert-Jan de Vries, Klaus L. Leenders, Michael Biehl

Publikováno v: Computer Methods and Programs in Biomedicine, 225:107042. ELSEVIER IRELAND LTD

Background and Objectives 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) combined with principal component analysis (PCA) has been applied to identify disease-related brain patterns in neurodegenerative disorders such as Parkinson’

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd62cc088a960d142382e1683262424
https://doi.org/10.1016/j.cmpb.2022.107042