Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Frans Van Valen"'
Autor:
Frans van Valen, Henning Harrer, Marc Hotfilder, Uta Dirksen, Thomas Pap, George Gosheger, Hans-Ulrich Humpf, Heribert Jürgens
Publikováno v:
Sarcoma, Vol 2012 (2012)
Insulin-like growth factor 1 (IGF1) reputedly opposes chemotoxicity in Ewing sarcoma family of tumor (ESFT) cells. However, the effect of IGF1 on apoptosis induced by apoptosis ligand 2 (Apo2L)/tumor necrosis factor (TNF-) related apoptosis-inducing
Externí odkaz:
https://doaj.org/article/5ff089b82a6b4f6a84993e3fcfa25dd8
Autor:
James W. Wells, Mark C. Gebhardt, Stephen L. Lessnick, Frans Van Valen, Kyle Robichaud, Elaine P. Lunsford, Taha Merghoub, Regina P. O'Sullivan, Ryan M. Porter, Fangjun Liu, Christopher H. Evans
PDF file, 59K, Supplementary Figure S1. A typical example of Bilateral Inguinal Lymph node size 8 days after vaccination with the native peptide QQNPSYDSV (#14) or its modified derivative YLNPSVDSV (#24).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517b24e416a4ca9ab4dbd192f596b240
https://doi.org/10.1158/1078-0432.22455225.v1
https://doi.org/10.1158/1078-0432.22455225.v1
Autor:
James W. Wells, Mark C. Gebhardt, Stephen L. Lessnick, Frans Van Valen, Kyle Robichaud, Elaine P. Lunsford, Taha Merghoub, Regina P. O'Sullivan, Ryan M. Porter, Fangjun Liu, Christopher H. Evans
Purpose: The Ewing sarcoma family of tumors (ESFT) comprises a group of aggressive, malignant bone, and soft tissue tumors that predominantly affect children and young adults. These tumors frequently share expression of the EWS-FLI-1 translocation, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a172191674f786558fd7011a5a486e9a
https://doi.org/10.1158/1078-0432.c.6522963
https://doi.org/10.1158/1078-0432.c.6522963
Autor:
Christopher Poremba, Helmut E. Gabbert, Guido Reifenberger, Pancras C. W. Hogendoorn, Kevin A. W. Lee, Shuen-Kuei Liao, Laura Spahn, Barbara Selle, Claudia Baer, Frans van Valen, Reinhard Voss, Martin Eisenacher, Eberhard Korsching, Raihanatou Diallo, Yvonne Braun, Daniel H. Wai, Kristin Brachwitz, Karl-Ludwig Schaefer
Supplementary Table 1 from Expression Profiling of t(12;22) Positive Clear Cell Sarcoma of Soft Tissue Cell Lines Reveals Characteristic Up-Regulation of Potential New Marker Genes Including ERBB3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532b21bae7e74408bce09209c1f8d107
https://doi.org/10.1158/0008-5472.22363856.v1
https://doi.org/10.1158/0008-5472.22363856.v1
Autor:
Christopher Poremba, Helmut E. Gabbert, Guido Reifenberger, Pancras C. W. Hogendoorn, Kevin A. W. Lee, Shuen-Kuei Liao, Laura Spahn, Barbara Selle, Claudia Baer, Frans van Valen, Reinhard Voss, Martin Eisenacher, Eberhard Korsching, Raihanatou Diallo, Yvonne Braun, Daniel H. Wai, Kristin Brachwitz, Karl-Ludwig Schaefer
Supplementary Table 2 from Expression Profiling of t(12;22) Positive Clear Cell Sarcoma of Soft Tissue Cell Lines Reveals Characteristic Up-Regulation of Potential New Marker Genes Including ERBB3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105db743b7638f9afa908954e7a93526
https://doi.org/10.1158/0008-5472.22363853.v1
https://doi.org/10.1158/0008-5472.22363853.v1
Autor:
Christopher Poremba, Helmut E. Gabbert, Guido Reifenberger, Pancras C. W. Hogendoorn, Kevin A. W. Lee, Shuen-Kuei Liao, Laura Spahn, Barbara Selle, Claudia Baer, Frans van Valen, Reinhard Voss, Martin Eisenacher, Eberhard Korsching, Raihanatou Diallo, Yvonne Braun, Daniel H. Wai, Kristin Brachwitz, Karl-Ludwig Schaefer
Clear cell sarcoma of soft tissue (CCSST), also known as malignant melanoma of soft parts, represents a rare lesion of the musculoskeletal system usually affecting adolescents and young adults. CCSST is typified by a chromosomal t(12;22)(q13;q12) tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89849ba552ad932111874e89b06c008
https://doi.org/10.1158/0008-5472.c.6493922
https://doi.org/10.1158/0008-5472.c.6493922
Autor:
Regina P. O'Sullivan, Stephen L. Lessnick, James W. Wells, Frans van Valen, Fangjun Liu, Taha Merghoub, Kyle Robichaud, Ryan M. Porter, Mark C. Gebhardt, Christopher H. Evans, Elaine P. Lunsford
Publikováno v:
Clinical Cancer Research. 18:5341-5351
Purpose: The Ewing sarcoma family of tumors (ESFT) comprises a group of aggressive, malignant bone, and soft tissue tumors that predominantly affect children and young adults. These tumors frequently share expression of the EWS-FLI-1 translocation, w
Autor:
Klaus-Michael Debatin, Frans van Valen, Liubov Bogatyreva, Nora Hipp, Jörg Fiedler, Markus Rojewski, Joachim Wahl, Petra Boukamp, Christian Beltinger
Publikováno v:
International Journal of Cancer. 127:1295-1307
The Ewing family of tumors (EFT) is an important group of pediatric malignancies with a guarded prognosis. Little is known about the heterogeneity of EFT cells, and the cellular origin of EFT is disputed. We now add evidence that EFT are heterogeneou
Autor:
Marc Hotfilder, Christopher Poremba, Winfried Winkelmann, Borna Truckenbrod, Frans van Valen, Simone Fulda, Karl-Ludwig Schäfer, Klaus-Michael Debatin
Publikováno v:
International Journal of Cancer. 107:929-940
Although TRAIL/Apo2L preferably induces apoptosis in tumour cells without toxicity in normal cells, many tumour cell types display TRAIL/Apo2L resistance. Whether TRAIL/Apo2L in combination with chemotherapy may overcome TRAIL/Apo2L resistance while
Autor:
Falk Wilfert, Christian Rübe, Winfried Winkelmann, Frans van Valen, Normann Willich, Claudia E. Rübe, Andreas Schuck, Heribert Jürgens, Jan Palm
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 56:1414-1425
Purpose In the present study, we examined human Ewing’s sarcoma (ES) and peripheral primitive neuroectodermal tumor (pPNET) cell lines that are able to produce TNF-α as part of the response to irradiation. Radiation-induced tumor cell production o