Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Frans M van de Rijke"'
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Akademický článek
Non-random mtDNA segregation patterns indicate a metastable heteroplasmic segregation unit in m.3243A>G cybrid cells.
Autor: Anton K Raap, Roshan S Jahangir Tafrechi, Frans M van de Rijke, Angela Pyle, Carolina Wählby, Karoly Szuhai, Raimond B G Ravelli, René F M de Coo, Harsha K Rajasimha, Mats Nilsson, Patrick F Chinnery, David C Samuels, George M C Janssen
Publikováno v: PLoS ONE, Vol 7, Iss 12, p e52080 (2012)
Many pathogenic mitochondrial DNA mutations are heteroplasmic, with a mixture of mutated and wild-type mtDNA present within individual cells. The severity and extent of the clinical phenotype is largely due to the distribution of mutated molecules be
Externí odkaz: https://doaj.org/article/7159e41e8e794a30ab231bb6bbd37c83
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2
Site-Specific Identification of SUMO-2 Targets in Cells Reveals an Inverted SUMOylation Motif and a Hydrophobic Cluster SUMOylation Motif
Autor: Joost Schimmel, Frans M. van de Rijke, Matthias Mann, Alfred C.O. Vertegaal, Hans van Dam, Florian Gnad, Ivan Matic, Ivor .A. Hendriks, Maria A. van Santen
Publikováno v: Mol Cell
Molecular Cell, 39(4), 641-652
Reversible protein modification by small ubiquitin-like modifiers (SUMOs) is critical for eukaryotic life. Mass spectrometry-based proteomics has proven effective at identifying hundreds of potential SUMO target proteins. However, direct identificati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0dd6fe7ef60ac7e888aa80c26a25347
https://doi.org/10.1016/j.molcel.2010.07.026
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3
Single-cell A3243G Mitochondrial DNA Mutation Load Assays for Segregation Analysis
Autor: Willem C. R. Sloos, George M.C. Janssen, Carolina Wählby, Frans M. van de Rijke, Marchien van de Sande, Chatarina Larsson, Roshan S. Jahangir Tafrechi, Anton K. Raap, Amin Allallou
Publikováno v: Journal of Histochemistry & Cytochemistry. 55:1159-1166
Segregation of mitochondrial DNA (mtDNA) is an important underlying pathogenic factor in mtDNA mutation accumulation in mitochondrial diseases and aging, but the molecular mechanisms of mtDNA segregation are elusive. Lack of high-throughput single-ce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef41190d03bcadfc482ef5dc35a26a6c
https://doi.org/10.1369/jhc.7a7282.2007
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4
A multiplexed and miniaturized serological tuberculosis assay identifies antigens that discriminate maximally between TB and non-TB sera
Autor: Arend H. J. Kolk, Cornelis H. Hokke, Catharina E. Jacobi, Nico Nagelkerke, Frans M. van de Rijke, Rob P.M. van Gijlswijk, Anton K. Raap, Todd L. Lowary, Jacques Veuskens, S. Kuijper, Ben J. Appelmelk, Hans J. Tanke, Miao Tong, Sjaak van de Werken
Publikováno v: Tong, M, Jacobi, C E, van de Rijke, F M, Kuijper, S, van de Werken, S, Lowary, T L, Hokke, C H, Appelmelk, B J, Nagelkerke, N J, Tanke, H J, van Gijlswijk, R P & Veuskens, J 2005, ' A multiplexed and miniaturized serological tuberculosis assay identifies antigens that discriminate maximally between TB and non-TB sera ', Journal of Immunological Methods, vol. 301, no. 1-2, pp. 154-163 . https://doi.org/10.1016/j.jim.2005.04.004
Journal of Immunological Methods, 301(1-2), 154-163. Elsevier
Journal of immunological methods, 301(1-2), 154-163. Elsevier
We have developed a multiplexed and miniaturized TB serological assay with the aim of identifying (combinations of) antigens that maximally discriminate between TB and non-TB patients. It features a microarray accommodating 54 TB antigens, less than
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8000e44d17a5feb82afebe017123bbcd
https://doi.org/10.1016/j.jim.2005.04.004
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5
Fluorescence in situ hybridization using horseradish peroxidase-labeled oligodeoxynucleotides and tyramide signal amplification for sensitive DNA and mRNA detection
Autor: Frans M. van de Rijke, Mariëtte P.C. van de Corput, A. K. Raap, Rob P.M. van Gijlswijk, Roeland W. Dirks
Publikováno v: Histochemistry and Cell Biology. 110:431-437
We have used horseradish peroxidase-labeled 40 mer oligodeoxynucleotides (HRP-ODNs) specific for the human cytomegalovirus immediate early gene (HCMV-IE) and a novel dinitrophenol-tyramide signal amplification reagent (DNP-TSA plus) to evaluate their
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441fd4b18ea648d0643562e51fe2063d
https://doi.org/10.1007/s004180050304
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7
Microscopy and image analysis of fibre-FISH
Autor: Frans M. van de Rijke, Hans J. Tanke, Ralph J. Florijn, Gert-Jan B. van Ommen, Anton K. Raap, Hans Vrolijk, Johan T. den Dunnen
Publikováno v: Bioimaging. 4:84-92
In this paper the aspects of image acquisition, processing and analysis for DNA-fibre mapping are described. As the nature and the quality of the fibre-FISH signals (given its resolution range of 1–500 kb) may vary to a great extent, an interactive
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54619573b79444f52542be9ec0a05026
https://doi.org/10.1002/1361-6374(199606)4:2<84::aid-bio6>3.0.co
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8
Sample preparation and in situ hybridization techniques for automated molecular cytogenetic analysis of white blood cells
Autor: Willem C. R. Sloos, Anton K. Raap, Frans M. van de Rijke, Hans Vrolijk, Hans J. Tanke
Publikováno v: Cytometry. 24:151-157
With the advent of in situ hybridization techniques for the analysis of chromosome copy number or structure in interphase cells, the diagnostic and prognostic potential of cytogenetics has been augmented considerably. In theory, the strategies for de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c5e46cebc32bcc60e166d8bac4649d78
https://doi.org/10.1002/(sici)1097-0320(19960601)24:2<151::aid-cyto7>3.0.co
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9
Non-Random mtDNA Segregation Patterns Indicate a Metastable Heteroplasmic Segregation Unit in m.3243A > G Cybrid Cells
Autor: David C. Samuels, Patrick F. Chinnery, George M.C. Janssen, Raimond B. G. Ravelli, Roshan S. Jahangir Tafrechi, René de Coo, Frans M. van de Rijke, Carolina Wählby, Mats Nilsson, Angela Pyle, Karoly Szuhai, Harsha Rajasimha, Anton K. Raap
Publikováno v: PLoS ONE
PLoS ONE, Vol 7, Iss 12, p e52080 (2012)
PLoS ONE, 7(12)
Many pathogenic mitochondrial DNA mutations are heteroplasmic, with a mixture of mutated and wild-type mtDNA present within individual cells. The severity and extent of the clinical phenotype is largely due to the distribution of mutated molecules be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b14bf808922de514c5f90c4d244376
https://doi.org/10.1371/journal.pone.0052080
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10
Bicolor fluorescence in situ hybridization to intron and exon mRNA sequences
Autor: Frans M. van de Rijke, Mels van der Ploeg, Anton K. Raap, Roeland W. Dirks, R. Boom, C. J. A. Sol
Publikováno v: Experimental Cell Research. 197:319-322
The technique of nonradioactive in situ hybridization has been used to visualize the DNA and mRNA expression of human cytomegalovirus (HCMV) immediate early antigen (IEA) in a transfected rat fibroblast cell line. Expression of the transfected HCMV i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf11849f61fc64655f22f17e19d11e44
https://doi.org/10.1016/0014-4827(91)90439-2
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