The MicroRNA Landscape of Acute Beta Cell Destruction in Type 1 Diabetic Recipients of Intraportal Islet Grafts

Autor: Geert A. Martens, Geert Stangé, Lorenzo Piemonti, Jasper Anckaert, Zhidong Ling, Daniel G. Pipeleers, Frans K. Gorus, Pieter Mestdagh, Dieter De Smet, Jo Vandesompele, Bart Keymeulen, Sarah Roels

Publikováno v: Cells, Vol 10, Iss 7, p 1693 (2021)

Ongoing beta cell death in type 1 diabetes (T1D) can be detected using biomarkers selectively discharged by dying beta cells into plasma. microRNA-375 (miR-375) ranks among the top biomarkers based on studies in animal models and human islet transpla

Externí odkaz: https://doaj.org/article/0140f1c493544f638afd98132e0142d6

Correction: Prediction of Impending Type 1 Diabetes through Automated Dual-Label Measurement of Proinsulin:C-Peptide Ratio.

Autor: Annelien Van Dalem, Simke Demeester, Eric V Balti, Bart Keymeulen, Pieter Gillard, Bruno Lapauw, Christophe De Block, Pascale Abrams, Eric Weber, Ilse Vermeulen, Pieter De Pauw, Daniël Pipeleers, Ilse Weets, Frans K Gorus, Belgian Diabetes Registry

Publikováno v: PLoS ONE, Vol 12, Iss 6, p e0179108 (2017)

[This corrects the article DOI: 10.1371/journal.pone.0166702.].

Externí odkaz: https://doaj.org/article/49f8a95ae3c9442db3fe144e2edcd453

Contributors

Autor: Peter Abrams, Joel T. Adler, Rodolfo Alejandro, Mohamed Alibashe-Ahmed, Ana Alvarez, Takayuki Anazawa, Axel Andres, Barbara Antonioli, Alan Apete, David A. Axelrod, Lionel Badet, David Baidal, Kaylene Barrera, Pierre-Yves Benhamou, Thierry Berney, Alain Gerald Bertoni, Federico Bertuzzi, Ugo Boggi, Caroline Bonner, Adel Bozorgzadeh, Julien Branchereau, Jonathan Bromberg, George W. Burke, Fanny Buron, Robert Caiazzo, Rossana Caldara, Stephanie S. Camhi, Diego Cantarovich, Massimo Cardillo, D. Castanares-Zapatero, Pierre Cattan, Suresh Rama Chandran, Erin Chang, Linda Chen, Mikael Chetboun, Pratik Choudhary, Gaetano Ciancio, Maria Pia Cicalese, Antonio Citro, C. Collienne, Caterina Conte, Claire Counter, Khaled Z. Dajani, Carly M. Darden, Francesco De Cobelli, Eelco J.P. de Koning, Hector De Leon, Nathalie Delalleau, Laura DiChiacchio, Jason B. Doppenberg, Cinthia B. Drachenberg, Erica Dugnani, Ty B. Dunn, Marten A. Engelse, Ahmed Farag, Alan Farney, Anne Elizabeth Farrow, Ibrahim Fathi, Jose Figueiro, Anneliese Flatt, Georgia Fousteri, Jonathan A. Fridell, Peter J. Friend, Giacomo Gastaldi, Valery Gmyr, Javier Gonzalez, Jeevan Prakash Gopal, Frans K. Gorus, Masafumi Goto, Mitsukazu Gotoh, Michel Greget, Dominique Grenet, Paolo Antonio Grossi, Rainer W.G. Gruessner, Angelika C. Gruessner, David I. Harriman, Wayne J. Hawthorne, Jarl Hellman, Brenda Lee Holbert, Thomas Hubert, Sara Iacopi, Marco Infante, Peter Jacob, Paul Johnson, Raja Kandaswamy, Georges Karam, Dixon B. Kaufman, W.F. Kendall Jr, Clark D. Kensinger, Norma S. Kenyon, Julie Kerr-Conte, Delphine Kervella, Laurence Kessler, Romain Kessler, Bart Keymeulen, Olle Korsgren, Sandrine Lablanche, Muhaib Lakhani, Neeraj Lalwani, P.F. Laterre, Michael C. Lawrence, Frances Tangherlini Lee, Roger Lehmann, Elina Linetsky, Barbara Ludwig, Torbjörn Lundgren, Xunrong Luo, SriGita Madiraju, Paola Maffi, Paola Magistretti, Kristell Le Mapihan, James F. Markmann, Geert Martens, Paulo N. Martins, Francesco Antonio Mazzotta, Kavya Chitra Mekala, Raffaella Melzi, Alessia Mercalli, Paolo Monti, Mahmoud Morsi, Irene Mosca, M. Mourad, Anand S. Rathnasamy Muthusamy, Rita Nano, Bashoo Naziruddin, Christian Noel, John O’Callaghan, Jon S. Odorico, Anne Olland, E.C. Opara, Giuseppe Orlando, Nathalia Padilla, John C. Papadimitriou, Vassilios E. Papalois, Klearchos K. Papas, Gianni Pasquetti, François Pattou, Silvia Pellegrini, Nadine Pernin, Vittorio Grazio Perrone, Lorenzo Piemonti, Rutger Ploeg, John A. Powelson, Alberto Pugliese, Shanthini K. Rajan, Karthik V. Ramanathan, Violeta Raverdy, Robert R. Redfield, John Renz, Michael R. Rickels, Charles G. Rickert, Camillo Ricordi, Jeffrey Rogers, Joseph R. Scalea, Jesse D. Schold, Hanne Scholz, Antonio Secchi, Oscar K. Serrano, A.M. James Shapiro, Sidharth Sharma, Edward Sharples, James A.M. Shaw, Sanjay Sinha, Carlo Socci, Jean-Paul G. Squifflet, Peter G. Stock, Robert J. Stratta, David E.R. Sutherland, Manfredi Tesauro, Olivier Thaunat, Julien Thévenet, Christoph Troppmann, Marie-Christine Vantyghem, Francesco Vendrame, Massimo Venturini, Rodrigo Vianna, Fabio Vistoli, Bengt von Zur-Mühlen, X. Wittebole, Anne Wojtusciszyn, Arya Zarinsefat, Asha Zimmerman

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e433aba2e57eb1cb1a8a229cb3ca7c3d
https://doi.org/10.1016/b978-0-12-814833-4.09992-5

Clusters of conserved beta cell marker genes for assessment of beta cell phenotype.

Autor: Geert A Martens, Lei Jiang, Karine H Hellemans, Geert Stangé, Harry Heimberg, Finn C Nielsen, Olivier Sand, Jacques Van Helden, Leentje Van Lommel, Frans Schuit, Frans K Gorus, Daniel G Pipeleers

Publikováno v: PLoS ONE, Vol 6, Iss 9, p e24134 (2011)

BACKGROUND AND METHODOLOGY: The aim of this study was to establish a gene expression blueprint of pancreatic beta cells conserved from rodents to humans and to evaluate its applicability to assess shifts in the beta cell differentiated state. Genome-

Externí odkaz: https://doaj.org/article/3f92a588ceaa4e308a290e027fb10a8b

Cellular islet autoimmunity associates with clinical outcome of islet cell transplantation.

Autor: Volkert A L Huurman, Robert Hilbrands, Gabriëlle G M Pinkse, Pieter Gillard, Gaby Duinkerken, Pieter van de Linde, Petronella M W van der Meer-Prins, Minke F J Versteeg-van der Voort Maarschalk, Koen Verbeeck, Behrooz Z Alizadeh, Chantal Mathieu, Frans K Gorus, Dave L Roelen, Frans H J Claas, Bart Keymeulen, Daniel G Pipeleers, Bart O Roep

Publikováno v: PLoS ONE, Vol 3, Iss 6, p e2435 (2008)

Islet cell transplantation can cure type 1 diabetes (T1D), but only a minority of recipients remains insulin-independent in the following years. We tested the hypothesis that allograft rejection and recurrent autoimmunity contribute to this progressi

Externí odkaz: https://doaj.org/article/6265b621f04542d88c64037910f72a6e