Zobrazeno 1 - 10
of 395
pro vyhledávání: '"Frans J. Walther"'
Autor:
Xueyu Chen, Dongshan Han, Xuan Wang, Xuemei Huang, Zilu Huang, Yijun Liu, Junyan Zhong, Frans J. Walther, Chuanzhong Yang, Gerry T. M. Wagenaar
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Ibuprofen is a nonsteroidal anti-inflammatory drug that is commonly used to stimulate closure of a patent ductus arteriosus (PDA) in very premature infants and may lead to aberrant neonatal lung development and bronchopulmonary dy
Externí odkaz:
https://doaj.org/article/11f3eded1e27400186e965236fe8a969
Autor:
Frans J. Walther, Alan J. Waring
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 163 (2024)
Lung surfactant is a mixture of lipids and proteins and is essential for air breathing in mammals. The hydrophobic surfactant proteins B and C (SP-B and SP-C) assist in reducing surface tension in the lung alveoli by organizing the surfactant lipids.
Externí odkaz:
https://doaj.org/article/f125b4b9a8e749b0b65a2aa1465ae5f3
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Dry powder (DP) synthetic lung surfactant may be an effective means of noninvasive delivery of surfactant therapy to premature infants supported with nasal continuous positive airway pressure (nCPAP) in low-resource settings. Meth
Externí odkaz:
https://doaj.org/article/97f6dc42a0d94f2b9cbd06ac56033ac5
Autor:
Robert M. DiBlasi, Coral N. Crandall, Rebecca J. Engberg, Kunal Bijlani, Dolena Ledee, Masaki Kajimoto, Frans J. Walther
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2368 (2023)
Aerosolized lung surfactant therapy during nasal continuous positive airway pressure (CPAP) support avoids intubation but is highly complex, with reported poor nebulizer efficiency and low pulmonary deposition. The study objective was to evaluate par
Externí odkaz:
https://doaj.org/article/c9b6b0005dde47cab0eea1a5ac0c192a
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Optimal functionality of synthetic lung surfactant for treatment of respiratory distress syndrome in preterm infants largely depends on the quality and quantity of the surfactant protein B (SP-B) peptide mimic and the lipid mixtur
Externí odkaz:
https://doaj.org/article/d5695b7ec7e047a3af4f54ff01738ea1
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Inhalation of dry powder synthetic lung surfactant may assist spontaneous breathing by providing noninvasive surfactant therapy for premature infants supported with nasal continuous positive airway pressure. Surfactant was formulated using s
Externí odkaz:
https://doaj.org/article/d0447baa3af84c81a39cbf1394a11162
Autor:
Frans J. Walther, Alan J. Waring
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
After shifting away from invasive mechanical ventilation and intratracheal instillation of surfactant toward non-invasive ventilation with nasal CPAP and less invasive surfactant administration in order to prevent bronchopulmonary dysplasia in preter
Externí odkaz:
https://doaj.org/article/bc973d5021d04dad9871c24aedf955dd
Publikováno v:
BMC Pediatrics, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Objective To evaluate the association between hematological parameters at birth and the risk of moderate-severe bronchopulmonary dysplasia (BPD) in a cohort of extremely preterm infants. Methods This is a retrospective study of all extremely
Externí odkaz:
https://doaj.org/article/eee98a7a3ce147f18ae6519c93232cb3
Autor:
Xueyu Chen, Junyan Zhong, Dongshan Han, Fang Yao, Jie Zhao, Gerry. T. M. Wagenaar, Chuanzhong Yang, Frans J. Walther
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Bronchopulmonary dysplasia (BPD) is a neonatal chronic lung disease characterized by an arrest in alveolar and vascular development. BPD is secondary to lung immaturity, ventilator-induced lung injury, and exposure to hyperoxia in extremely premature
Externí odkaz:
https://doaj.org/article/c026c973338e4d86807f76dfcd381bae
Autor:
Frans J. Walther, Monik Gupta, Michael M. Lipp, Holly Chan, John Krzewick, Larry M. Gordon, Alan J. Waring
Publikováno v:
Gates Open Research, Vol 3 (2019)
Background: The development of synthetic lung surfactant for preterm infants has focused on peptide analogues of native surfactant proteins B and C (SP-B and SP-C). Non-invasive respiratory support with nasal continuous positive airway pressure (nCPA
Externí odkaz:
https://doaj.org/article/3e7a9d84c2c1481298d9eeb569e5223d