Predicting Fish Acute Toxicity Using a Fish Gill Cell Line-Based Toxicity Assay

Autor: Melanie Knöbel, Katrin Tanneberger, Joop L. M. Hermens, Kristin Schirmer, Frans J. M. Busser, Theo L. Sinnige

Publikováno v: Environmental Science & Technology. 47:1110-1119

The OECD test guideline 203 for determination of fish acute toxicity requires substantial numbers of fish and uses death as an apical end point. One potential alternative are fish cell lines; however, several studies indicated that these appear up to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a9271a55a054a54e37ad07e93621d6
https://doi.org/10.1021/es303505z

Toward More Useful In Vitro Toxicity Data with Measured Free Concentrations

Autor: Richard H. M. M. Schreurs, Bart van der Burg, Frans J. M. Busser, Joop L. M. Hermens, Paul T. Van Der Saag, Minne B. Heringa

Publikováno v: Environmental Science & Technology. 38:6263-6270

In vitro assays and computer models are promising alternatives for in vivo animal testing, but the power of these alternative methods to predict in vivo risk is still very limited. One step forward is to make the outcome of in vitro assays (such as m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a32f416ab89bb876608ce54e77d91cb
https://doi.org/10.1021/es049285w

Surrogate parameter for the baseline toxicity content of contaminated water: simulating the bioconcentration of mixtures of pollutants and counting molecules

Autor: Frans J. M. Busser, Henk J. M. Verhaar, Joop L. M. Hermens

Publikováno v: Environmental sciencetechnology. 29(3)

A large part of all environmental pollutants can be classified as narcosis-type chemicals with regard to acute aquatic toxicity. This baseline, or narcosis-type, toxicity is generally assumed to be brought about through one and the same mechanism. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72729bf9934a86f1ec6bf15f46256edb
https://pubmed.ncbi.nlm.nih.gov/22200282

Poly(dimethylsiloxane) as passive sampler material for hydrophobic chemicals: effect of chemical properties and sampler characteristics on partitioning and equilibration times

Autor: Frans J. M. Busser, Thomas L. ter Laak, Joop L. M. Hermens

Publikováno v: Analytical chemistry. 80(10)

Information about sampling rates and equilibration times of passive samplers is essential in their calibration in field monitoring studies as well as sorption studies. The kinetics of a sampler depends on the distribution coefficient between the samp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f113311eefff1a94bb4670348929c07
https://pubmed.ncbi.nlm.nih.gov/18422340

Measured Pore-Water Concentrations Make Equilibrium Partitioning Work - A Data Analysis

Autor: Willem Seinen, Johannes Tolls, Philipp Mayer, Rik Kraaij, Frans J. M. Busser, A.C. Belfroid, Maarten Van Het Bolscher

Publikováno v: Kraaij, R, Mayer, P, Busser, F J M, Bolscher, M V H, Seinen, W, Tolls, J & Belfroid, A C 2003, ' Measured Pore-Water Concentrations Make Equilibrium Partitioning Work-A Data Analysis ', Environmental Science & Technology (Washington), vol. 37, no. 2, pp. 268-274 .

There is an increasing body of evidence that the bioaccumulation of sediment-associated hydrophobic organic compounds (HOCs) is strongly influenced by sequestration. At present, it is not known how equilibrium partitioning theory (EqP), the most comm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aaeb14a31f052d548cfd23a669b7f2c
https://pure.au.dk/portal/da/publications/measured-porewater-concentrations-make-equilibrium-partitioning-work--a-data-analysis(7c2026b0-7e9d-11dd-a5a8-000ea68e967b).html