Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Frans Delbeke"'
Publikováno v:
Forensic Toxicology. 30:106-113
A simple and robust liquid chromatographic-tandem mass spectrometric method was developed and validated for the direct quantification of the structural isomers morphine-3-glucuronide (M3G), morphine-6-glucuronide (M6G), and morphine in urine. Method
Quantitative detection of inhaled formoterol in human urine and relevance to doping control analysis
Publikováno v:
Drug Testing and Analysis. 4:449-454
Formoterol is a frequently prescribed β2-agonist used for the treatment of asthma. Due to performance-enhancing effects of some β2-agonists, formoterol appears on the prohibited list, published by the World Anti-doping Agency (WADA). Its therapeuti
Publikováno v:
Clinical Endocrinology. 75:134-140
Context Until now, the testosterone/epitestosterone (T/E) ratio is the main marker for the detection of testosterone (T) misuse in athletes. As this marker can be influenced by a number of confounding factors, additional steroid profile parameters in
Publikováno v:
Journal of Chromatography A. 1218:3306-3316
The use of performance enhancing drugs in sports is prohibited. For the detection of misuse of such substances gas chromatography or liquid chromatography coupled to mass spectrometry are the most frequently used detection techniques. In this work th
Publikováno v:
Analytical and Bioanalytical Chemistry. 401:421-432
This paper reviews the prevalence of legal and illegal stimulants in relation to doping-control analysis. Stimulants are among the oldest classes of doping agents, having been used since ancient times. Despite the ease with which they can be detected
Publikováno v:
Rapid Communications in Mass Spectrometry. 24:1133-1141
An accurate and precise method for the quantification of 11-nor-Delta(9)-tetrahydrocannabinol-9-carboxylic acid (THCA) in urine by liquid chromatography/tandem mass spectrometry (LC/MS/MS) for doping analysis purposes has been developed. The method i
Autor:
Geert Leroux-Roels, Oscar J. Pozo, Frans Delbeke, Leen Lootens, Philip Meuleman, Peter Van Eenoo, Pieter Van Renterghem
Publikováno v:
Drug Testing and Analysis. 1:531-537
Anabolic androgenic steroids are considered to be doping agents and are prohibited in sports. Their metabolism needs to be elucidated to allow for urinary detection by gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-tandem mass
Autor:
Félix Hernández, Leen Lootens, Koen Deventer, Peter Van Eenoo, Oscar J. Pozo, Philip Meuleman, Juan V. Sancho, Geert Leroux-Roels, Frans Delbeke, Susana Grimalt
Publikováno v:
Steroids. 74:837-852
The applicability of LC-MS/MS in precursor ion scan mode for the detection of urinary stanozolol metabolites has been studied. The product ion at m/z 81 has been selected as specific for stanozolol metabolites without a modification in A- or N-rings
Autor:
Philip Meuleman, Peter Van Eenoo, Frans Delbeke, Oscar J. Pozo, Leen Lootens, Geert Leroux-Roels
Publikováno v:
Clinical Chemistry. 55:1783-1793
Background: Adequate detection of designer steroids in the urine of athletes is still a challenge in doping control analysis and requires knowledge of steroid metabolism. In this study we investigated whether uPA+/+-SCID mice carrying functional prim
Autor:
Frans Delbeke, Wim Van Thuyne, Maria Kristina Parr, Peter Van Eenoo, Oscar J. Pozo, Juan V. Sancho, Koen Deventer, Leen Lootens, Félix Hernández, Wilhelm Schänzer, Philip Meuleman, Geert Leroux-Roels
Publikováno v:
Drug Metabolism and Disposition. 37:2153-2162
The misuse of the anabolic steroid methyltestosterone is currently routinely monitored in doping control laboratories by gas chromatography-mass spectrometry (GC-MS) of two of its metabolites: 17alpha-methyl-5beta-androstane-3alpha,17beta-diol and 17