Zobrazeno 1 - 10
of 367
pro vyhledávání: '"Frans C. S. Ramaekers"'
Autor:
Stefan G. C. Mestrum, Norbert C. J. de Wit, Eline M. P. Cremers, Roosmarie J. M. Drent, Frans C. S. Ramaekers, Anton H. N. Hopman, Math P. G. Leers
Publikováno v:
HemaSphere, Vol 6, Iss 12, p e804 (2022)
Externí odkaz:
https://doaj.org/article/b9e57974a5ba4b56be736fd375b52052
Autor:
Merel Stiekema, Frederik Houben, Fons Verheyen, Marcel Borgers, Julia Menzel, Martin Meschkat, Marc A. M. J. van Zandvoort, Frans C. S. Ramaekers, Jos L. V. Broers
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Invaginations of the nuclear membrane occur in different shapes, sizes, and compositions. Part of these pleiomorphic invaginations make up the nucleoplasmic reticulum (NR), while others are merely nuclear folds. We define the NR as tubular invaginati
Externí odkaz:
https://doaj.org/article/f25ba3c860b84e3dbfd64b5b246d97f8
Autor:
Jobran M. Moshi, Klaas J. Hoogduin, Monique Ummelen, Mieke E. R. Henfling, Manon vanEngeland, Kim A. D. Wouters, Hans Stoop, Imke Demers, Leendert H. J. Looijenga, Frans C. S. Ramaekers, Anton N. H. Hopman
Publikováno v:
Cancer Medicine, Vol 9, Iss 17, Pp 6330-6343 (2020)
Abstract Aims The dynamics and topographical distribution of SOX17 and SOX2 expression was studied in the transformation zone (TZ) of the uterine cervix. This TZ is a dynamic area where switches from glandular into squamous epithelium can be recogniz
Externí odkaz:
https://doaj.org/article/48b7637d65e54d66b12f87f63287acfd
Autor:
Verona E. Bergshoeff, Maschenka C. A. Balkenhol, Annick Haesevoets, Andrea Ruland, Michelene N. Chenault, Rik C. Nelissen, Carine J. Peutz, Ruud Clarijs, Jeroen A. W. M. Van der Laak, Robert P. Takes, Michiel W. Van den Brekel, Marie-Louise F. Van Velthuysen, Frans C. S. Ramaekers, Bernd Kremer, Ernst-Jan M. Speel
Publikováno v:
Cancers, Vol 14, Iss 13, p 3260 (2022)
Background: The definition of objective, clinically applicable evaluation criteria for FISH 1c/7c in laryngeal precursor lesions for the detection of chromosome instability (CI). Copy Number Variations (CNV) for chromosomes 1 and 7 reflect the genera
Externí odkaz:
https://doaj.org/article/3804e2d32a7746f0b73f158e41619af5
Autor:
Merel Stiekema, Frans C. S. Ramaekers, Dimitrios Kapsokalyvas, Marc A. M. J. van Zandvoort, Rogier J. A. Veltrop, Jos L. V. Broers
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10194 (2021)
A- and B-type lamins are type V intermediate filament proteins. Mutations in the genes encoding these lamins cause rare diseases, collectively called laminopathies. A fraction of the cells obtained from laminopathy patients show aberrations in the lo
Externí odkaz:
https://doaj.org/article/63d5639b3d0042c9bf6de6c6e041796f
Publikováno v:
Cells, Vol 9, Iss 8, p 1884 (2020)
The nuclear lamins are the major components of the nuclear lamina in the nuclear envelope. Lamins are involved in numerous functions, including a role in providing structural support to the cell and the mechanosensing of the cell. Mutations in the ge
Externí odkaz:
https://doaj.org/article/088868f644b7433b87f71fd1a90e0d8b
Autor:
Jobran M. Moshi, Monique Ummelen, Jos L. V. Broers, Frans C. S. Ramaekers, Anton H. N. Hopman
Publikováno v:
Histochemistry and Cell Biology. Springer Verlag
This study compares three different pretreatment protocols for the immunohistochemical detection of 5-methylcytosine (5-mC) and 5-hydroxymethylcytosine (5-hmC) in nuclear DNA. The human biological samples analyzed included formalin-fixed and paraffin
Autor:
Jobran M. Moshi, Monique Ummelen, Jos L. V. Broers, Frank Smedts, Koen K. Van de Vijver, Jack P. M. Cleutjens, Rogier J. N. T. M. Litjens, Frans C. S. Ramaekers, Anton H. N. Hopman
Publikováno v:
Histochemistry and Cell Biology, 158(6), 545-559. Springer Verlag
SOX2 expression in high-grade cervical intraepithelial neoplasia (CIN3) and cervical squamous cell carcinoma is increased compared to that in the normal cervical epithelium. However, data on the expression and histological distribution of SOX2 in squ
Autor:
Stefan G. C. Mestrum, Roanalis B. Y. Vanblarcum, Roosmarie J. M. Drent, Bert T. Boonen, Wouter L. W. van Hemert, Frans C. S. Ramaekers, Anton H. N. Hopman, Math P. G. Leers
Publikováno v:
Cytometry Part A, 101(7), 552-563. Wiley
Recent developments in clinical flow cytometry allow the simultaneous assessment of proliferative and anti-apoptotic activity in the different hematopoietic cell lineages and during their maturation process. This can further advance the flow cytometr
Publikováno v:
Blood Adv
Standardization of the detection and quantification of leukocyte differentiation markers by the EuroFlow Consortium has led to a major step forward in the integration of flow cytometry into classification of leukemia and lymphoma. In our opinion, thi