Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Franklyn Ngundam"'
Autor:
Diana Caridha, Mark Hickman, Lisa Xie, Franklyn Ngundam, Erin Milner, Amanda Schenk, Kirk Butler, Dylan Nugent, Patricia Lee, Norma Roncal, Susan Leed, Eve Hosford, Jangwoo Lee, Richard J. Sciotti, Gregory Reichard, Chad Black, Mara Kreishman-Deitrick, Qigui Li, Brian Vesely
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-15 (2019)
Abstract Background Rodent malaria models are extensively used to predict treatment outcomes in human infections. There is a constant need to improve and refine these models by innovating ways to apply new scientific findings and cutting edge technol
Externí odkaz:
https://doaj.org/article/b2caeece80d94ce2ab66bc1e98c7f17b
Autor:
Anny Fortin, Diana P Caridha, Susan Leed, Franklyn Ngundam, Jenell Sena, Tom Bosschaerts, Sandi Parriott, Mark R Hickman, Thomas H Hudson, Max Grogl
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 9, p e3144 (2014)
Cutaneous leishmaniasis (CL) represents a range of skin diseases caused by infection with Leishmania parasites and associated with tissue inflammation and skin ulceration. CL is clinically widespread in both the Old and New World but lacks treatments
Externí odkaz:
https://doaj.org/article/19b4a5713b574cbb908851985c685931
Autor:
Alicia Cawlfield, Dylan Nugent, Franklyn Ngundam, Kirk Butler, Brian Vesely, Diana Caridha, Tobin Rowland
Publikováno v:
Journal of medical entomology. 55(2)
Novel treatments for cutaneous leishmaniasis (CL) are needed, due to current lack of effective universal treatments, increasing resistance among the parasite, and toxic effects or impracticality of the current therapeutics. Models of direct infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb5ca1d1bb91bae28b2ccc5e9faeb06
https://pubmed.ncbi.nlm.nih.gov/29253231
https://pubmed.ncbi.nlm.nih.gov/29253231
Autor:
Diana, Caridha, Sandi, Parriot, Thomas H, Hudson, Thierry, Lang, Franklyn, Ngundam, Susan, Leed, Jenell, Sena, Michael, Harris, Michael, O'Neil, Richard, Sciotti, Lisa, Read, Herve, Lecoeur, Mark, Hickman, Max, Grogl
Publikováno v:
Antimicrobial Agents and Chemotherapy
In any drug discovery and development effort, a reduction in the time of the lead optimization cycle is critical to decrease the time to license and reduce costs. In addition, ethical guidelines call for the more ethical use of animals to minimize th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::501d8aa18dba6d45eb4bfbb0836ccf26
https://pubmed.ncbi.nlm.nih.gov/28137819
https://pubmed.ncbi.nlm.nih.gov/28137819
Autor:
Jay Moon, Franklyn Ngundam, Erin Milner, Erin Harris, Sandi Parriott, Richard J. Sciotti, Brittney Potter, Qigui Li, Patricia J. Lee, Michael T. O’Neil, Michael P. Kozar, Sean Gardner, Diana Caridha, Jennifer M. Auschwitz, Anchalee Tangteung, Kristina Grauer, Mark Hickman, Geoffrey S. Dow, Susan E. Leed, Jason C. Sousa, Brandon S. Pybus, Victor Melendez
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 37:17-22
Ketotifen is known to exhibit antimalarial activity in mouse and monkey malaria models. However, the low plasma levels and short half life of the drug do not adequately explain its in vivo efficacy. We synthesized most of the known metabolites of ket
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff844de657e2fb34fa0cd6b909b0398
https://doi.org/10.1007/s13318-012-0080-2
https://doi.org/10.1007/s13318-012-0080-2
Autor:
Franklyn Ngundam, Sandi Parriott, Anny Fortin, Max Grogl, Thomas H. Hudson, Diana Caridha, Jenell Sena, Tom Bosschaerts, Susan E. Leed, Mark Hickman
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 8, Iss 9, p e3144 (2014)
PLoS Neglected Tropical Diseases, Vol 8, Iss 9, p e3144 (2014)
Background Cutaneous leishmaniasis (CL) represents a range of skin diseases caused by infection with Leishmania parasites and associated with tissue inflammation and skin ulceration. CL is clinically widespread in both the Old and New World but lacks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14af5987a2bc8a5a184d4ee2212bbdf1
http://europepmc.org/articles/PMC4161350
http://europepmc.org/articles/PMC4161350