Tox induces T cell IL-10 production in a BATF-dependent manner

Autor: D. Alejandro Canaria, J. Alejandra Rodriguez, Luopin Wang, Franklin J. Yeo, Bingyu Yan, Mengbo Wang, Charlotte Campbell, Majid Kazemian, Matthew R. Olson

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

Tox is a member of the high mobility group (HMG)-Box transcription factors and plays important roles in thymic T cell development. Outside of the thymus, however, Tox is also highly expressed by CD8 and CD4 T cells in various states of activation and

Externí odkaz: https://doaj.org/article/19fe360441634a0699b88d25342143cf

4-Octyl Itaconate Attenuates Neuroinflammation in Experimental Autoimmune Encephalomyelitis Via Regulating Microglia.

Autor: Zhao N; Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China., Yi M; Department of The Key Laboratory for Human Disease Gene Study of Sichuan Province and the Department of Laboratory Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, 611731, China.; Research Unit for Blindness Prevention of the Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan, China., Zhang LJ; Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China., Zhang QX; Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China., Yang L; Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China. yangli2001@tmu.edu.cn.

Publikováno v: Inflammation [Inflammation] 2024 May 18. Date of Electronic Publication: 2024 May 18.