Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Franklin J. Moy"'
Autor:
Noemi D. Paguigan, Franklin J. Moy, Cedric J. Pearce, Huzefa A. Raja, Nicholas H. Oberlies, Nadja B. Cech, Wilson C. Brooks
Publikováno v:
Magnetic Resonance in Chemistry. 55:670-676
Analysis of complex mixtures is a common challenge in natural products research. Quantitative nuclear magnetic resonance spectroscopy offers analysis of complex mixtures at early stages and with benefits that are orthogonal to more common methods of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ca9fdbff7532cb753e8572c301038e9
https://doi.org/10.1002/mrc.4571
https://doi.org/10.1002/mrc.4571
Autor:
Desiree H.H. Tsao, Arthur Lee, Lori Krim Gavrin, Franklin J. Moy, Zhang Bao Xu, John C. McKew, Lidia Mosyak, Elizabeth Kieras, Wayne Stochaj, Annette Sievers
Publikováno v:
Journal of Medicinal Chemistry. 53:1238-1249
To aid in the pursuit of selective kinase inhibitors, we have developed a unique ATP site binder tool for the detection of binders outside the ATP site by nuclear magnetic resonance (NMR). We report here the novel synthesis that led to this paramagne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f003cb00b2d9a32bb90459fe0d5ba83c
https://doi.org/10.1021/jm901525b
https://doi.org/10.1021/jm901525b
Autor:
Elena G. Novikova, Jaison Jacob, Alessandro Mascioni, Karl Malakian, Franklin J. Moy, Yingxia Wen, Mininni Terri L, Pamela Fink, Rosaria Camarda, Susan K. Hoiseth, Deborah A. Dilts, Shuo L. Lin, Ellen Murphy, Scott Sigethy, Gary W. Zlotnick, Breagh E. Bentley, Lisa K. McNeil, Viktoria Gusarova, Désirée H. H. Tsao
Publikováno v:
Journal of Biological Chemistry. 284:8738-8746
LP2086 is a family of outer membrane lipoproteins from Neisseria meningitidis, which elicits bactericidal antibodies and are currently undergoing human clinical trials in a bivalent formulation where each antigen represents one of the two known LP208
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8413724cf730643fe45e47ec0e1e0635
https://doi.org/10.1074/jbc.m808831200
https://doi.org/10.1074/jbc.m808831200
Publikováno v:
Biochemistry. 39:13365-13375
The application of deuterium labeling and residual dipolar coupling constants in combination with other structural information has demonstrated the potential for significantly expanding the range of viable protein targets for structural analysis by N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067ecb83d84a256bc11e27204c461f39
https://doi.org/10.1021/bi001658s
https://doi.org/10.1021/bi001658s
Autor:
Smruti A. Desai, Elvyra J. Noronha, Vera Rebmann, Qinwei Zhou, Soldano Ferrone, Robert Powers, Xinhui Wang, Franklin J. Moy, Hans Grosse-Wilde
Publikováno v:
The Journal of Immunology. 165:3275-3283
The association of HLA class I heavy chains with β2-microglobulin (β2m) changes their antigenic profile. As a result, Abs react with either β2m-free or β2m-associated HLA class I heavy chains. An exception to this rule is the mAb TP25.99, which r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0794985942b80b35573329e4ab16232f
https://doi.org/10.4049/jimmunol.165.6.3275
https://doi.org/10.4049/jimmunol.165.6.3275
Publikováno v:
Biochemistry. 39:9146-9156
ZipA, an essential component of cell division in Escherichia coli, interacts with the FtsZ protein at the midcell in one of the initial steps of septum formation. The high-resolution solution structure of the 144-residue C-terminal domain of E. coli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc6095213a443338ff0bb99001b208c
https://doi.org/10.1021/bi0009690
https://doi.org/10.1021/bi0009690
Autor:
Pranab K. Chanda, Mark I. Cockett, Philip G. Jones, Franklin J. Moy, Semus Simon, Wade Edris, Robert Powers, Kim Mason
Publikováno v:
Biochemistry. 39:7063-7073
Heterotrimeric guanine nucleotide-binding proteins (G-proteins) are transducers in many cellular transmembrane signaling systems where regulators of G-protein signaling (RGS) act as attenuators of the G-protein signal cascade by binding to the Galpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989e85e4b71212697540ffc417f79284
https://doi.org/10.1021/bi992760w
https://doi.org/10.1021/bi992760w
Publikováno v:
Biochemistry. 37:10581-10588
Oncostatin M (OM) is a member of the cytokine family which regulates the proliferation and differentiation of a variety of cell types and includes interleukin-6 (IL-6), leukemia inhibitory factor (LIF), and granulocyte-colony stimulating factor (G-CS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95000af01739d123d3478eda08ab0303
https://doi.org/10.1021/bi9727444
https://doi.org/10.1021/bi9727444
Autor:
Pranab K. Chanda, Michael R. Pisano, Robert Powers, Scott Cosmi, Charlotte Urbano, Franklin J. Moy, Jim Wilhelm
Publikováno v:
Biochemistry. 37:1495-1504
The high-resolution solution structure of the inhibitor-free catalytic fragment of human fibroblast collagenase (MMP-1), a protein of 18.7 kDa, which is a member of the matrix metalloproteinase family, has been determined using three-dimensional hete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebb3460e9a88d0854244cfd7992f333
https://doi.org/10.1021/bi972181w
https://doi.org/10.1021/bi972181w
Autor:
and Avner Yayon, Peter Böhlen, Andrew P. Seddon, Michal Safran, Franklin J. Moy, Robert Powers, David Aviezer, Doug Kitchen
Publikováno v:
Biochemistry. 36:4782-4791
Interaction of basic fibroblast growth factor (FGF-2) with heparin or heparan sulfate proteoglycans (HSPGs) is required for receptor activation and initiation of biological responses. To gain insight into the mechanism of activation of the FGF recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6b3b26b85fec653b2842de836691a1
https://doi.org/10.1021/bi9625455
https://doi.org/10.1021/bi9625455