Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Franklin J. Bauer"'
Autor:
James W. Firman, David J. Ebbrell, Franklin J. Bauer, Maria Sapounidou, Geoff Hodges, Bruno Campos, Jayne Roberts, Steve Gutsell, Paul C. Thomas, Mark Bonnell, Mark T. D. Cronin
Publikováno v:
Environmental sciencetechnology. 56(24)
The performance of chemical safety assessment within the domain of environmental toxicology is often impeded by a shortfall of appropriate experimental data describing potential hazards across the many compounds in regular industrial use. In silico s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685f578a6bb6ae13e3f36054fecc2820
https://pubmed.ncbi.nlm.nih.gov/36445296
https://pubmed.ncbi.nlm.nih.gov/36445296
Autor:
Mark T.D. Cronin, Franklin J. Bauer, Mark Bonnell, Bruno Campos, David J. Ebbrell, James W. Firman, Steve Gutsell, Geoff Hodges, Grace Patlewicz, Maria Sapounidou, Nicoleta Spînu, Paul C. Thomas, Andrew P. Worth
Publikováno v:
Regulatory Toxicology and Pharmacology. 135:105249
Structure-activity relationships (SARs) in toxicology have enabled the formation of structural rules which, when coded as structural alerts, are an essential tool in in silico toxicology. Whilst other in silico methods have approaches for their evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2c754db0a3692430e9a43d0a7f965f
https://doi.org/10.1016/j.yrtph.2022.105249
https://doi.org/10.1016/j.yrtph.2022.105249
Publikováno v:
Computational Toxicology
Computational Toxicology, 2018, 7, pp.36-45. ⟨10.1016/j.comtox.2018.06.004⟩
Computational Toxicology, 2018, 7, pp.36-45. ⟨10.1016/j.comtox.2018.06.004⟩
Knowing the mechanism of action (MechoA) of substances is a crucial first step in determining an Adverse Outcome Pathway and in risk assessment, especially when using in silico models to predict (eco)toxicity. We developed a set of structural alerts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6989b15baf292677522c0ee041a0fb
https://doi.org/10.1016/j.comtox.2018.06.004
https://doi.org/10.1016/j.comtox.2018.06.004
Publikováno v:
Integrated environmental assessment and management. 15(1)
In silico methods are typically underrated in the current risk assessment paradigm, as evidenced by the recent document from the European Chemicals Agency (ECHA) on animal alternatives, in which quantitative structure-activity relationships (QSARs) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21987673c82df6e676389777c3f68c81
https://pubmed.ncbi.nlm.nih.gov/30447098
https://pubmed.ncbi.nlm.nih.gov/30447098