Zobrazeno 1 - 10 of 382 pro vyhledávání: '"Frankish N"'
1
Akademický článek
Molecular structure studies of (1,2)-2-benzyl-2,3-dihydro-2-(1H-inden-2-yl)-1H-inden-1-ol
Autor: Zhang, T., Paluch, Krzysztof J., Scalabrino, G., Frankish, N., Healy, A.M., Sheridan, H.
Yes
The single enantiomer (1S,2S)-2-benzyl-2,3-dihydro-2-(1H-inden-2-yl)-1H-inden-1-ol (2), has recently been synthesized and isolated from its corresponding diastereoisomer (1). The molecular and crystal structures of this novel compound have b
Externí odkaz: http://hdl.handle.net/10454/9427
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2
Akademický článek
Design, synthesis and biological evaluation of a novel bioactive indane scaffold 2-(diphenylmethylene)c-2,3-dihydro-1H-inden-1-one with potential anticancer activity.
Autor: Zhang T; School of Food Science and Environmental Health, Technological University Dublin, Grangegorman, Dublin 7, D07 ADY7, Ireland; The Trinity Centre for Natural Products Research (NatPro), School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin 2, D02 PN40, Ireland; Drug Discovery Group, School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, D02 PN40, Ireland. Electronic address: tao.zhang@TUDublin.ie., Bandero V; Drug Discovery Group, School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, D02 PN40, Ireland. Electronic address: banderv@tcd.ie., Corcoran C; Drug Discovery Group, School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, D02 PN40, Ireland. Electronic address: corcorcl@tcd.ie., Obaidi I; The Trinity Centre for Natural Products Research (NatPro), School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin 2, D02 PN40, Ireland; College of Pharmacy, University of Babylon, Babylon, Iraq. Electronic address: obaidii@tcd.ie., Ruether M; School of Chemistry, Trinity College Dublin, Dublin 2, Ireland. Electronic address: ruetherm@tcd.ie., O'Brien J; School of Chemistry, Trinity College Dublin, Dublin 2, Ireland. Electronic address: jeobrien@tcd.ie., O'Driscoll L; Drug Discovery Group, School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, D02 PN40, Ireland. Electronic address: lodrisc@tcd.ie., Frankish N; Drug Discovery Group, School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, D02 PN40, Ireland. Electronic address: nfrnkish@tcd.ie., Sheridan H; The Trinity Centre for Natural Products Research (NatPro), School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin 2, D02 PN40, Ireland; Drug Discovery Group, School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, D02 PN40, Ireland. Electronic address: hsheridn@tcd.ie.
Publikováno v: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2023 Sep 01; Vol. 188, pp. 106529. Date of Electronic Publication: 2023 Jul 17.
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3
Akademický článek
A series of 1, 2-coupled indane dimers with mast cell stabilisation and smooth muscle relaxation properties
Autor: Sheridan, H., Walsh, J.J., Jordan, M., Cogan, C., Frankish, N.
Publikováno v: In European Journal of Medicinal Chemistry 2009 44(12):5018-5022
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4
Akademický článek
Synthesis and pharmacological activity of aminoindanone dimers and related compounds
Autor: Sheridan, H., Butterly, S., Walsh, J.J., Cogan, C., Jordan, M., Nolan, O., Frankish, N.
Publikováno v: In Bioorganic & Medicinal Chemistry 2008 16(1):248-254
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5
Akademický článek
Roseoside Is a Bioactive Compound in Kirengeshoma koreana Nakai Extract with Potent In Vitro Antiviral Activity Against Hepatitis C Virus.
Autor: Lee, Jun-Kyu1 (AUTHOR) wnsrb0855@naver.com, Choi, Ji-Wan1 (AUTHOR) chlwldhks14@naver.com, Park, InWha2 (AUTHOR) inwha129@skku.edu, Kim, Na-Eun1 (AUTHOR) kne951027@naver.com, Kwon, Hak Cheol2 (AUTHOR) hkwon@kist.re.kr, Kwon, Jaeyoung2 (AUTHOR) kjy1207@kist.re.kr, Song, Yoon-Jae1 (AUTHOR) kjy1207@kist.re.kr
Publikováno v: Molecules. Nov2024, Vol. 29 Issue 21, p5130. 13p.
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6
Akademický článek
Bioactive indanes: insight into the bioactivity of indane dimers related to the lead anti-inflammatory molecule PH46A.
Autor: Chan K; School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute (TBSI), Trinity College Dublin, Dublin 2, Ireland., Frankish N; School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute (TBSI), Trinity College Dublin, Dublin 2, Ireland., Zhang T; School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute (TBSI), Trinity College Dublin, Dublin 2, Ireland.; School of Food Science and Environmental Health, Technological University Dublin, Dublin 1, Ireland., Ece A; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Biruni University, Topkapi-Istanbul, Turkey., Cannon A; Department of Surgery, School of Medicine, Trinity Translation Medicine Institute (TTMI), St James's Hospital, Dublin 8, Ireland., O'Sullivan J; Department of Surgery, School of Medicine, Trinity Translation Medicine Institute (TTMI), St James's Hospital, Dublin 8, Ireland., Sheridan H; School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute (TBSI), Trinity College Dublin, Dublin 2, Ireland.
Publikováno v: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2020 Jul; Vol. 72 (7), pp. 927-937. Date of Electronic Publication: 2020 Apr 16.
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7
Akademický článek
Bioactive indanes: Development and validation of an LC-MS/MS bioanalytical method for the determination of PH46A, a new potential anti-inflammatory agent, in dog and rat plasma and its application to a pharmacokinetic study in dog.
Autor: Scalabrino GA; Trino Therapeutics Ltd, The Tower, Trinity Technology and Enterprise Campus, Dublin 2, Ireland., Zhang T; Trino Therapeutics Ltd, The Tower, Trinity Technology and Enterprise Campus, Dublin 2, Ireland; School of Food Science and Environmental Health, City Campus, Technological University Dublin, Dublin 1, Ireland., Frankish N; Trino Therapeutics Ltd, The Tower, Trinity Technology and Enterprise Campus, Dublin 2, Ireland; Drug Discovery Group, School of Pharmacy and Pharmaceutical Sciences & Trinity Biomedical Sciences Institute, Trinity College, Dublin 2, Ireland. Electronic address: nfrnkish@tcd.ie., Sheridan H; Trino Therapeutics Ltd, The Tower, Trinity Technology and Enterprise Campus, Dublin 2, Ireland; Drug Discovery Group, School of Pharmacy and Pharmaceutical Sciences & Trinity Biomedical Sciences Institute, Trinity College, Dublin 2, Ireland. Electronic address: hsheridn@tcd.ie.
Publikováno v: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2020 Feb 05; Vol. 179, pp. 113011. Date of Electronic Publication: 2019 Nov 28.
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8
Akademický článek
Anti-Allergic and Anti-Inflammatory Signaling Mechanisms of Natural Compounds/Extracts in In Vitro System of RBL-2H3 Cell: A Systematic Review.
Autor: Rana, Tekan S.1 (AUTHOR) tsrana@aggies.ncat.edu, Bansode, Rishipal R.1 (AUTHOR), Williams, Leonard L.1 (AUTHOR) llw@ncat.edu
Publikováno v: Cells (2073-4409). Aug2024, Vol. 13 Issue 16, p1389. 29p.
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9
Akademický článek
Bioactive Indanes: Proof of Concept Study for Enantioselective Synthetic Routes to PH46A, a New Potential Anti-Inflammatory Agent.
Autor: Zhang T; Trino Therapeutics Ltd., The Tower, Trinity Technology and Enterprise Campus, Dublin 2, D02 W272, Ireland. zhangt@tcd.ie., Scalabrino G; Trino Therapeutics Ltd., The Tower, Trinity Technology and Enterprise Campus, Dublin 2, D02 W272, Ireland. gaiascal@gmail.com., Frankish N; Trino Therapeutics Ltd., The Tower, Trinity Technology and Enterprise Campus, Dublin 2, D02 W272, Ireland. nfrnkish@tcd.ie.; Novel Drug Discovery Group, School of Pharmacy and Pharmaceutical Sciences & Trinity Biomedical Sciences Institute, Trinity College, Dublin 2, D02 W272, Ireland. nfrnkish@tcd.ie., Sheridan H; Trino Therapeutics Ltd., The Tower, Trinity Technology and Enterprise Campus, Dublin 2, D02 W272, Ireland. hsheridn@tcd.ie.; Novel Drug Discovery Group, School of Pharmacy and Pharmaceutical Sciences & Trinity Biomedical Sciences Institute, Trinity College, Dublin 2, D02 W272, Ireland. hsheridn@tcd.ie.
Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2018 Jun 21; Vol. 23 (7). Date of Electronic Publication: 2018 Jun 21.
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10
Akademický článek
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