Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Frankie H. F. Lee"'
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-12 (2019)
Abstract Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by silencing of the FMR1 gene and subsequent loss of its protein product, fragile X retardation protein (FMRP). One of the most robust neuropathological findings in post-mortem
Externí odkaz:
https://doaj.org/article/d46609e3d43e411fb838076a0de30381
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-12 (2019)
Molecular Brain
Molecular Brain
Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by silencing of the FMR1 gene and subsequent loss of its protein product, fragile X retardation protein (FMRP). One of the most robust neuropathological findings in post-mortem human FX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f9f621988e2920b5176ca9de0ca19a
http://link.springer.com/article/10.1186/s13041-019-0478-8
http://link.springer.com/article/10.1186/s13041-019-0478-8
Publikováno v:
Science Signaling. 12
Disruption of γ-aminobutyric acid (GABA)-ergic interneuron migration is implicated in various neurodevelopmental disorders, including autism spectrum disorder and schizophrenia. The dopamine D1 receptor (D1R) promotes GABAergic interneuron migration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72786eaccd23392674fd2acda199b807
https://doi.org/10.1126/scisignal.aau9122
https://doi.org/10.1126/scisignal.aau9122
Autor:
Charlie T.G. Campbell, Jing Liu, Shupeng Li, Kerry J. Ressler, Frankie H. F. Lee, Suvercha Pasricha, Ping Su, Dongxu Zhai, Anlong Jiang, Fang Liu, Terence K. Y. Lai, Albert H.C. Wong, Haiyin Li, WeiDong Yong
Publikováno v:
J Clin Invest
Posttraumatic stress disorder (PTSD) can develop after exposure to severe psychological trauma, leaving patients with disabling anxiety, nightmares, and flashbacks. Current treatments are only partially effective, and development of better treatments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c264cb0fef4232c41e775d136878f233
https://pubmed.ncbi.nlm.nih.gov/31929189
https://pubmed.ncbi.nlm.nih.gov/31929189
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
There is strong evidence indicating neuroinflammation is an important mediator in multiple sclerosis (MS), with astrogliosis playing a significant role in this process. Surprisingly, astrocytes exert paradoxical roles during disease development, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b176b0d183ce80e5b7bd4f4b7a540f
https://doi.org/10.1038/s41598-018-31318-4
https://doi.org/10.1038/s41598-018-31318-4
Autor:
Li Zhang, Cheryl A. D'Souza, Zhengping Jia, Albert H.C. Wong, Shouping Zhang, Ping Su, Dongxu Zhai, Fang Liu, Frankie H. F. Lee
Publikováno v:
Annals of Clinical and Translational Neurology
Objective Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. The pathophysiological mechanism of MS remains largely unknown and no cure is available. Current clinical treatments for MS modulate the immune syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79041a6aa3e2a912c92836682c0d16f8
https://doi.org/10.1002/acn3.182
https://doi.org/10.1002/acn3.182
Publikováno v:
Receptor-Receptor Interactions in the Central Nervous System ISBN: 9781493985753
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::358400eda13ba2b1740b09e32dc42acd
https://doi.org/10.1007/978-1-4939-8576-0_11
https://doi.org/10.1007/978-1-4939-8576-0_11
Autor:
Min Wang, Albert H.C. Wong, Stephen S. G. Ferguson, John C. Roder, Shupeng Li, Ping Su, Tatiana V. Lipina, Paul J. Fletcher, Hailong Zhang, Sheng Chen, Terence K. Y. Lai, José N. Nobrega, Dongxu Zhai, Fang Liu, Frankie H. F. Lee
Publikováno v:
Neuron. 84(6):1302-1316
Summary Current antipsychotic drugs primarily target dopamine D2 receptors (D2Rs), in conjunction with other receptors such as those for serotonin. However, these drugs have serious side effects such as extrapyramidal symptoms (EPS) and diabetes. Ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::599c994a2c4a789237b497ccbd0b8c87
Publikováno v:
Scientific Reports
GluA2-containing AMPA receptors (AMPARs) play a critical role in various aspects of neurodevelopment. However, the molecular mechanisms underlying these processes are largely unknown. We report here that the interaction between GluA2 and glyceraldehy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba28eaf4fb0776e169036d59fa800e0
Autor:
Tze Jen Chow, Brandon Abbs, Hiroaki Hori, Ahmet Aktener, Meina Quan, Jared W. Young, Charlotte Gayer-Anderson, Saddichha Sahoo, Maurice Cabanis, Hiroyuki Uchida, Rachael K. Blackman, Adegoke Oloruntoba Adelufosi, Frankie H. F. Lee, Kristen M. Haut, Joshua T. Kantrowitz, Anne O'Shea, Laura M. Tully, Rashmin Achalia, Ashleigh Lin, Felipe V. Gomes, Savita G. Bhakta, Ricardo E. Carrión, Gregory P. Strauss, Aleksandra Szczepankiewicz, Lena Palaniyappan, Antonella Trotta, Lynn E. DeLisi, Emre Bora, Min Soo Byun, Taishiro Kishimoto, Eva Velthorst, Sonia Ruiz de Azúa, Monika Dmitrzak-Weglarz, Natalie J. Beveridge, Christina A. Castellani, Andrew Thompson, Maria D. Rubio
Publikováno v:
Paediatrics Publications
Schizophrenia research, 141(1), E1-E24. Elsevier
Schizophrenia research, 141(1), E1-E24. Elsevier
The 3rd Schizophrenia International Research Society Conference was held in Florence, Italy, April 14-18, 2012 and this year had as its emphasis, "The Globalization of Research". Student travel awardees served as rapporteurs for each oral session and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7113b734730b47e54fcbe34140a7095a
https://doi.org/10.1016/j.schres.2012.07.024
https://doi.org/10.1016/j.schres.2012.07.024