Malaria parasite evades mosquito immunity by glutaminyl cyclase-mediated posttranslational protein modification.

Autor: Kolli SK; Malaria Research Group, Department of Parasitology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Molina-Cruz A; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD, 20852., Araki T; Department of Parasitology, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo 162-8640, Japan., Geurten FJA; Malaria Research Group, Department of Parasitology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Ramesar J; Malaria Research Group, Department of Parasitology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Chevalley-Maurel S; Malaria Research Group, Department of Parasitology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Kroeze HJ; Malaria Research Group, Department of Parasitology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Bezemer S; Malaria Research Group, Department of Parasitology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., de Korne C; Malaria Research Group, Department of Parasitology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands.; Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Withers R; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD, 20852., Raytselis N; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD, 20852., El Hebieshy AF; Oncode Institute, Leiden University Medical Center, Leiden, 2333 ZC, The Netherlands.; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, 2333 ZC, The Netherlands., Kim RQ; Oncode Institute, Leiden University Medical Center, Leiden, 2333 ZC, The Netherlands.; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, 2333 ZC, The Netherlands., Child MA; Department of Life Sciences, Imperial College London, London, SW7 2AZ, United Kingdom., Kakuta S; Laboratory of Morphology and Image Analysis, Research Support Center, Juntendo University Graduate School of Medicine, Bunkyo, Tokyo 113-8421, Japan., Hisaeda H; Department of Parasitology, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo 162-8640, Japan., Kobayashi H; Department of Pathology, National Institute of Infectious Diseases, Shinjukuku, Tokyo 162-8640, Japan., Annoura T; Department of Parasitology, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo 162-8640, Japan., Hensbergen PJ; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Franke-Fayard BM; Malaria Research Group, Department of Parasitology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Barillas-Mury C; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD, 20852., Scheeren FA; Department of Dermatology, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands., Janse CJ; Malaria Research Group, Department of Parasitology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Aug 30; Vol. 119 (35), pp. e2209729119. Date of Electronic Publication: 2022 Aug 22.

Combinatorial Tim-3 and PD-1 activity sustains antigen-specific Th1 cell numbers during blood-stage malaria.

Autor: Dookie RS; Faculty of Biology, Medicine and Health, The Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, UK., Villegas-Mendez A; Faculty of Biology, Medicine and Health, The Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, UK., Kroeze H; Leiden malaria group, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands., Barrett JR; The Jenner Institute, University of Oxford, Oxford, UK., Draper SJ; The Jenner Institute, University of Oxford, Oxford, UK., Franke-Fayard BM; Leiden malaria group, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands., Janse CJ; Leiden malaria group, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands., MacDonald AS; Faculty of Biology, Medicine and Health, The Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, UK., Couper KN; Faculty of Biology, Medicine and Health, The Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, UK.

Publikováno v: Parasite immunology [Parasite Immunol] 2020 Sep; Vol. 42 (9), pp. e12723. Date of Electronic Publication: 2020 May 25.

OX40 Stimulation Enhances Protective Immune Responses Induced After Vaccination With Attenuated Malaria Parasites.

Autor: Othman AS; Leiden Malaria Research Group, Parasitology, Leiden University Medical Center, Leiden, Netherlands.; Faculty of Health Sciences, Universiti Sultan Zainal Abidin, Terengganu, Malaysia., Franke-Fayard BM; Leiden Malaria Research Group, Parasitology, Leiden University Medical Center, Leiden, Netherlands., Imai T; Leiden Malaria Research Group, Parasitology, Leiden University Medical Center, Leiden, Netherlands., van der Gracht ETI; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, Netherlands., Redeker A; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, Netherlands., Salman AM; Leiden Malaria Research Group, Parasitology, Leiden University Medical Center, Leiden, Netherlands.; The Jenner Institute, University of Oxford, Oxford, United Kingdom., Marin-Mogollon C; Leiden Malaria Research Group, Parasitology, Leiden University Medical Center, Leiden, Netherlands., Ramesar J; Leiden Malaria Research Group, Parasitology, Leiden University Medical Center, Leiden, Netherlands., Chevalley-Maurel S; Leiden Malaria Research Group, Parasitology, Leiden University Medical Center, Leiden, Netherlands., Janse CJ; Leiden Malaria Research Group, Parasitology, Leiden University Medical Center, Leiden, Netherlands., Arens R; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, Netherlands., Khan SM; Leiden Malaria Research Group, Parasitology, Leiden University Medical Center, Leiden, Netherlands.

Publikováno v: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2018 Jul 19; Vol. 8, pp. 247. Date of Electronic Publication: 2018 Jul 19 (Print Publication: 2018).

Rapid Generation of Marker-Free P. falciparum Fluorescent Reporter Lines Using Modified CRISPR/Cas9 Constructs and Selection Protocol.

Autor: Mogollon CM; Leiden Malaria Research Group, Department of Parasitology, Leiden University Medical Center (LUMC), Leiden, The Netherlands., van Pul FJ; Leiden Malaria Research Group, Department of Parasitology, Leiden University Medical Center (LUMC), Leiden, The Netherlands., Imai T; Leiden Malaria Research Group, Department of Parasitology, Leiden University Medical Center (LUMC), Leiden, The Netherlands., Ramesar J; Leiden Malaria Research Group, Department of Parasitology, Leiden University Medical Center (LUMC), Leiden, The Netherlands., Chevalley-Maurel S; Leiden Malaria Research Group, Department of Parasitology, Leiden University Medical Center (LUMC), Leiden, The Netherlands., de Roo GM; Department of Hematology, Leiden University Medical Center (LUMC), Leiden, The Netherlands., Veld SA; Department of Hematology, Leiden University Medical Center (LUMC), Leiden, The Netherlands., Kroeze H; Leiden Malaria Research Group, Department of Parasitology, Leiden University Medical Center (LUMC), Leiden, The Netherlands., Franke-Fayard BM; Leiden Malaria Research Group, Department of Parasitology, Leiden University Medical Center (LUMC), Leiden, The Netherlands., Janse CJ; Leiden Malaria Research Group, Department of Parasitology, Leiden University Medical Center (LUMC), Leiden, The Netherlands., Khan SM; Leiden Malaria Research Group, Department of Parasitology, Leiden University Medical Center (LUMC), Leiden, The Netherlands.

Publikováno v: PloS one [PLoS One] 2016 Dec 20; Vol. 11 (12), pp. e0168362. Date of Electronic Publication: 2016 Dec 20 (Print Publication: 2016).

Vital and dispensable roles of Plasmodium multidrug resistance transporters during blood- and mosquito-stage development.

Autor: Rijpma SR; Department of Pharmacology and Toxicology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., van der Velden M; Department of Pharmacology and Toxicology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Annoura T; Department of Tropical Medicine, The Jikei University School of Medicine, Post code 105-8461 Nishi-shinbashi 3-25-8, Minato-ku, Tokyo, Japan., Matz JM; Department of Medical Microbiology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Kenthirapalan S; Parasitology Unit, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117, Berlin, Germany., Kooij TW; Department of Medical Microbiology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands.; Centre for Molecular and Biomolecular Informatics, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Matuschewski K; Parasitology Unit, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117, Berlin, Germany.; Institute of Biology, Humboldt University, 10117, Berlin, Germany., van Gemert GJ; Department of Medical Microbiology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., van de Vegte-Bolmer M; Department of Medical Microbiology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Siebelink-Stoter R; Department of Medical Microbiology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Graumans W; Department of Medical Microbiology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Ramesar J; Leiden Malaria Research Group, Parasitology, Center of Infectious Diseases, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333, ZA, Leiden, The Netherlands., Klop O; Leiden Malaria Research Group, Parasitology, Center of Infectious Diseases, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333, ZA, Leiden, The Netherlands., Russel FG; Department of Pharmacology and Toxicology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Sauerwein RW; Department of Medical Microbiology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands., Janse CJ; Leiden Malaria Research Group, Parasitology, Center of Infectious Diseases, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333, ZA, Leiden, The Netherlands., Franke-Fayard BM; Leiden Malaria Research Group, Parasitology, Center of Infectious Diseases, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333, ZA, Leiden, The Netherlands., Koenderink JB; Department of Pharmacology and Toxicology, Radboud University Medical Center, Geert-Grooteplein 28, 6525, GA, Nijmegen, The Netherlands.

Publikováno v: Molecular microbiology [Mol Microbiol] 2016 Jul; Vol. 101 (1), pp. 78-91. Date of Electronic Publication: 2016 May 23.