Výsledky vyhledávání - "Franka H. van der Linden"

Akademický článek

A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium

Autor: Franka H. van der Linden, Eike K. Mahlandt, Janine J. G. Arts, Joep Beumer, Jens Puschhof, Saskia M. A. de Man, Anna O. Chertkova, Bas Ponsioen, Hans Clevers, Jaap D. van Buul, Marten Postma, Theodorus W. J. Gadella, Joachim Goedhart

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)

Currently, genetically encoded calcium indicators are not suitable for direct quantification. Here the authors engineer a fluorescence lifetime imaging calcium biosensor, Turquoise Calcium Fluorescence LIfeTime Sensor (Tq-Ca-FLITS), and measure intra

Externí odkaz: https://doaj.org/article/28e02e090b82435fa3bc07ed281bc827

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Visualizing endogenous Rho activity with an improved localization-based, genetically encoded biosensor

Autor: Werner J. van der Meer, Simon Tol, Eike K. Mahlandt, Jaap D. van Buul, Franka H van der Linden, Theodorus W. J. Gadella, Janine J. G. Arts, Joachim Goedhart

Publikováno v: Journal of cell science, 134(17):jcs258823.. Company of Biologists Ltd
Journal of Cell Science, 134(17):258823. Company of Biologists Ltd
Journal of Cell Science
article-version (VoR) Version of Record

Rho GTPases are regulatory proteins, which orchestrate cell features such as morphology, polarity and movement. Therefore, probing Rho GTPase activity is key to understanding processes such as development and cell migration. Localization-based report

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2562c53b256ee5a71a0532038caed7ff
https://pure.amc.nl/en/publications/visualizing-endogenous-rho-activity-with-an-improved-localizationbased-genetically-encoded-biosensor(5ebcbd54-fbcc-45ee-8f6c-da6e3ec0d3a8).html

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Author Reply to Peer Reviews of Visualizing endogenous RhoA activity with an improved localization-based, genetically encoded biosensor

Autor: Joachim Goedhart, Theodorus W. J. Gadella, Jaap D. van Buul, Simon Tol, Franka H. van der Linden, Werner J. van der Meer, Janine J. G. Arts, Eike K. Mahlandt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fcc8bce5ea22625f122de703d01d5b26
https://doi.org/10.15252/rc.2022658936

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High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells

Publikováno v: Cell, 181(6), 1291-1306.e19. Elsevier B.V.
Cell, 181(6), 1291-+. Cell Press
Cell

Enteroendocrine cells (EECs) sense intestinal content and release hormones to regulate gastrointestinal activity, systemic metabolism, and food intake. Little is known about the molecular make-up of human EEC subtypes and the regulated secretion of i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb3dc1f58bdcd8d9787afa61b297e1c
https://pure.knaw.nl/portal/en/publications/73363b0c-8425-47f7-bb59-62156970642e

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Efficient simultaneous excision of multiple selectable marker cassettes using I-SceI-induced double-strand DNA breaks inSaccharomyces cerevisiae

Autor: Franka H. van der Linden, Pascale Daran-Lapujade, Niels G. A. Kuijpers, Jack T. Pronk, Daniel Solis-Escalante, Jean-Marc Daran

Publikováno v: FEMS Yeast Research. 14:741-754

Large strain construction programs and functional analysis studies are becoming commonplace in Saccharomyces cerevisiae and involve construction of strains that carry multiple selectable marker genes. Extensive strain engineering is, however, severel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9da3b6725362852057d7e066f056086
https://doi.org/10.1111/1567-1364.12162

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