Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Frank-D. Goebel"'
Autor:
C Russo, Ulrike Protzer, Antonio Cosma, Sarah Kutscher, Johannes R. Bogner, Dieter Hoffmann, Frank D. Goebel, Tanja Bauer, Simone Allgayer, Claudia J. Dembek, Volker Erfle
Publikováno v:
Journal of Clinical Virology. 55:114-120
Background Several correlates of HIV control have been described; however their predictive values remain unclear, since most studies have been performed in cross-sectional settings. Objectives We evaluated the cause and consequence relationship betwe
Autor:
Christine Katlama, Richard Haubrich, Pedro Cahn, Frank D. Goebel, Johan Vingerhoets, Rekha Sinha, Fredy Suter, James Witek, Monika Peeters
Publikováno v:
HIV Therapy. 4:605-610
Aims: The impact of baseline characteristics on response to the non-nucleoside reverse transcriptase inhibitor etravirine was investigated at 48 weeks in the Phase III DUET trials. Methods: Logistic regression was used to examine the effect of baseli
Autor:
Heike Brackmann, Thomas Vollbrecht, Ulrich Seybold, Johannes R. Bogner, Joerg Roeling, Rika Draenert, Frank D. Goebel, Nadja Henrich
Publikováno v:
Journal of Medical Virology. 82:358-370
Excessive immune activation is a hallmark of chronic uncontrolled HIV infection. During the past years, growing evidence suggests that immune inhibitory signals also play an important role in progressive disease. However, the relationship between pos
Autor:
Frank D. Goebel, Thomas Lutz, Johannes Eisen, Volkmar Jacobi, Schlomo Staszewski, Markus Bickel, S Klauke, Stephan Zangos, Catherine M. Crespi, Gabi Knecht
Publikováno v:
Scandinavian Journal of Infectious Diseases. 40:36-39
Several studies have shown reduction of visceral adipose tissue (VAT) using recombinant human growth hormone (r-hGH) in HIV-1+ patients, but whether these effects are maintained after the end of treatment is unknown. In a prospective, randomized stud
Autor:
Frank D. Goebel, Volker Erfle, Antonio Cosma, Hermann M. Schätzl, Judith Seebach, Korbinian Strimmer, Dieter Hoffmann
Publikováno v:
The FASEB Journal. 22:437-444
With HIV persisting lifelong in infected persons, therapeutic vaccination is a novel alternative concept to control virus replication. Even though CD8 and CD4 cell responses to such immunizations have been demonstrated, their effects on virus replica
Autor:
Volker Erfle, Hermann M. Schätzl, Frank D. Goebel, Dirk H. Busch, Claudia Diemer, Caroline Staib, Gerd Sutter, Antonio Cosma, Rashmi Nagaraj, Franziska Wopfner
Publikováno v:
AIDS Research and Human Retroviruses. 23:782-793
The fear of malevolent use of variola virus by terrorists has led to the implementation of a health care worker vaccination program and to the consideration of vaccination for the general public. However, due to concerns about side effects of the cla
Autor:
Schlomo Staszewski, Stephan Zangos, Volkmar Jacobi, G Knecht, Frank D. Goebel, Thomas Lutz, Markus Bickel, S Klauke
Publikováno v:
HIV Medicine. 7:397-403
Background Several studies have shown beneficial effects of recombinant human growth hormone (r-hGH) in reducing visceral adipose tissue (VAT) in HIV-1-infected patients with lipodystrophy. Methods Patients were randomized to r-hGH 4 mg daily (group
Publikováno v:
Microbes and Infection. 7:1400-1404
Modified vaccinia virus Ankara (MVA) is a potent vaccine vector, which proved its safety, immunogenity and efficacy in preclinical and clinical studies. The rational for the development of a vaccine against HIV based on the regulatory protein Nef del
Publikováno v:
Der Internist. 46:892-898
Autor:
Antonio Cosma, Gerd Sutter, Volker Erfle, Frank D. Goebel, Rashmi Nagaraj, Silja Bühler, Jorma Hinkula, Dirk H. Busch
Publikováno v:
Vaccine. 22:21-29
Vaccination is currently considered as an additional therapeutic approach to stimulate HIV-specific immune response in subjects that could not naturally control HIV. Ten chronically HIV infected individuals have been vaccinated with a modified vaccin