Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Frank Zamudio"'
Autor:
Frank Zamudio, Anjanet R. Loon, Shayna Smeltzer, Khawla Benyamine, Nanda K. Navalpur Shanmugam, Nicholas J. F. Stewart, Daniel C. Lee, Kevin Nash, Maj-Linda B. Selenica
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-16 (2020)
Abstract Background Neuronal cytoplasmic inclusions containing TAR DNA-binding protein 43 (TDP-43) are a neuropathological feature of several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), an
Externí odkaz:
https://doaj.org/article/e33a410a6c39471d91bd94eaabb92019
Autor:
Aurelie Joly-Amado, Jordan Hunter, Zainuddin Quadri, Frank Zamudio, Patricia V. Rocha-Rangel, Deanna Chan, Anisha Kesarwani, Kevin Nash, Daniel C. Lee, Dave Morgan, Marcia N. Gordon, Maj-Linda B. Selenica
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Innate immune activation is a major contributor to Alzheimer's Disease (AD) pathophysiology, although the mechanisms involved are poorly understood. Chemokine C-C motif ligand (CCL) 2 is produced by neurons and glial cells and is upregulated in the A
Externí odkaz:
https://doaj.org/article/9b7b4496d3e9471cbe9ac95aad49ef5e
Autor:
Nanda K. Navalpur Shanmugam, Frank Zamudio, Kevin Nash, Khawla Benyamine, Anjanet R. Loon, Shayna Smeltzer, Daniel C. Lee, Nicholas J. F. Stewart, Maj-Linda B. Selenica
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-16 (2020)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Neuronal cytoplasmic inclusions containing TAR DNA-binding protein 43 (TDP-43) are a neuropathological feature of several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Alzheim
Autor:
Dale Chaput, Maj-Linda B. Selenica, Daniel C. Lee, Abraian Miller, Frank Zamudio, Shayna Smeltzer, Zainnudin Quadri
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Anisha Kesarwani, Zainuddin Quadri, Deanna Chan, Patricia V Rocha-Rangel, Marcia N. Gordon, Daniel C. Lee, Jordan Hunter, Kevin Nash, Frank Zamudio, Maj-Linda B. Selenica, Dave Morgan, Aurelie Joly-Amado
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Innate immune activation is a major contributor to Alzheimer's Disease (AD) pathophysiology, although the mechanisms involved are poorly understood. Chemokine C-C motif ligand (CCL) 2 is produced by neurons and glial cells and is upregulated in the A
Autor:
Sheba Saji, Nicholas J. F. Stewart, Jordan Hunter, Abraian Miller, Zainuddin Quadri, Maj-Linda B. Selenica, Daniel C. Lee, Shayna Smeltzer, Dale Chaput, Frank Zamudio
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1867:165939
TAR DNA-binding protein 43 (TDP-43) is a nuclear RNA/DNA binding protein involved in mRNA metabolism. Aberrant mislocalization to the cytoplasm and formation of phosphorylated/aggregated TDP-43 inclusions remains the hallmark pathology in a spectrum
Autor:
Daniel C. Lee, Melinda M. Peters, Edwin J. Weeber, Frank Zamudio, Nicholas Johnson, Kevin Nash, Jerry B. Hunt, Abraian Miller, Christopher M. Norris, Maj-Linda B. Selenica, Zainuddin Quadri, Susan D. Kraner, Steven B. Housley, Breanna Brown, Shayna Smeltzer
Publikováno v:
Mol Cell Neurosci
Aims The current study utilizes the adeno-associated viral gene transfer system in the CAMKIIα-tTA mouse model to overexpress human wild type TDP-43 (wtTDP-43) and α-synuclein (α-Syn) proteins. The co-existence of these proteins is evident in the
Autor:
Bryce A. Nordhues, Bo Zhang, Laura J. Blair, Frank Zamudio, Haley D Frauen, Chad A. Dickey, Yen-Chi Lin, Jonathan J. Sabbagh, Maj-Linda B. Selenica, Lidice D Hernandez, Sara Bijan
Publikováno v:
Acta Neuropathologica Communications
Introduction The blood-brain barrier (BBB) is damaged in tauopathies, including progressive supranuclear palsy (PSP) and Alzheimer’s disease (AD), which is thought to contribute to pathogenesis later in the disease course. In AD, BBB dysfunction ha