Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Frank Yates"'
Autor:
Héloïse Castiglione, Lucie Madrange, Thomas Lemonnier, Jean-Philippe Deslys, Frank Yates, Pierre-Antoine Vigneron
Publikováno v:
Organoids, Vol 3, Iss 2, Pp 113-125 (2024)
In recent years, 3D cell culture systems have emerged as sophisticated in vitro models, providing valuable insights into human physiology and diseases. The transition from traditional 2D to advanced 3D cultures has introduced novel obstacles, complic
Externí odkaz:
https://doaj.org/article/83bfa4b127b74b6c8acf7e17b8d6b9cb
Autor:
Mikaël Boullé, Alix Boucharlat, Ambre Leleu, Céline Banal, Aurélie Coussement, Marcel Hollenstein, Frank Yates, Nathalie Lefort, Fabrice Agou
Publikováno v:
Stem Cell Research, Vol 76, Iss , Pp 103350- (2024)
Human induced Pluripotent Stem Cells (hiPSCs) represent an invaluable source of primary cells to investigate development, establish cell and disease models, provide material for regenerative medicine and allow more physiological high-content screenin
Externí odkaz:
https://doaj.org/article/670abe90fddf4373896cf392088b9aec
Autor:
Léa Broca-Brisson, Rania Harati, Clémence Disdier, Orsolya Mozner, Romane Gaston-Breton, Auriane Maïza, Narciso Costa, Anne-Cécile Guyot, Balazs Sarkadi, Agota Apati, Matthew R Skelton, Lucie Madrange, Frank Yates, Jean Armengaud, Rifat Hamoudi, Aloïse Mabondzo
Publikováno v:
eLife, Vol 12 (2023)
Creatine transporter deficiency (CTD) is an X-linked disease caused by mutations in the SLC6A8 gene. The impaired creatine uptake in the brain results in intellectual disability, behavioral disorders, language delay, and seizures. In this work, we ge
Externí odkaz:
https://doaj.org/article/e52897c931c1438dbf89ad9807783b44
Autor:
Aurélie Mouka, Brahim Arkoun, Pauline Moison, Loïc Drévillon, Rafika Jarray, Sophie Brisset, Anne Mayeur, Jérôme Bouligand, Anne Boland-Auge, Jean-François Deleuze, Frank Yates, Thomas Lemonnier, Patrick Callier, Yannis Duffourd, Patrick Nitschke, Emmanuelle Ollivier, Arnaud Bourdin, John De Vos, Gabriel Livera, Gérard Tachdjian, Leïla Maouche-Chrétien, Lucie Tosca
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Despite increasing insight into the genetics of infertility, the developmental disease processes remain unclear due to the lack of adequate experimental models. The advent of induced pluripotent stem cell (iPSC) technology has provided a uni
Externí odkaz:
https://doaj.org/article/448defd6914244f9bd5854134c078283
Autor:
Héloïse Castiglione, Pierre-Antoine Vigneron, Camille Baquerre, Frank Yates, Jessica Rontard, Thibault Honegger
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2301 (2022)
There is an urgent need for predictive in vitro models to improve disease modeling and drug target identification and validation, especially for neurological disorders. Cerebral organoids, as alternative methods to in vivo studies, appear now as powe
Externí odkaz:
https://doaj.org/article/8bde374b2a47425dbe2a07653ff7b0a1
Autor:
Ferid Nassor, Rafika Jarray, Denis S. F. Biard, Auriane Maïza, Dulce Papy-Garcia, Serena Pavoni, Jean-Philippe Deslys, Frank Yates
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Human brain organoids (mini-brains) consist of self-organized three-dimensional (3D) neural tissue which can be derived from reprogrammed adult cells and maintained for months in culture. These 3D structures manifest substantial potential for the mod
Externí odkaz:
https://doaj.org/article/f8eef2923c7546f481175a47f14cc304
Autor:
Serena Pavoni, Rafika Jarray, Ferid Nassor, Anne-Cécile Guyot, Steve Cottin, Jessica Rontard, Jacqueline Mikol, Aloïse Mabondzo, Jean-Philippe Deslys, Frank Yates
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209150 (2018)
Human mini-brains (MB) are cerebral organoids that recapitulate in part the complexity of the human brain in a unique three-dimensional in vitro model, yielding discrete brain regions reminiscent of the cerebral cortex. Specific proteins linked to ne
Externí odkaz:
https://doaj.org/article/42b286926f5245ecbb4e3f4752714fc2
Autor:
Ladan Kobari, Frank Yates, Noufissa Oudrhiri, Alain Francina, Laurent Kiger, Christelle Mazurier, Shaghayegh Rouzbeh, Wassim El-Nemer, Nicolas Hebert, Marie-Catherine Giarratana, Sabine François, Alain Chapel, Hélène Lapillonne, Dominique Luton, Annelise Bennaceur-Griscelli, Luc Douay
Publikováno v:
Haematologica, Vol 97, Iss 12 (2012)
Background Human induced pluripotent stem cells offer perspectives for cell therapy and research models for diseases. We applied this approach to the normal and pathological erythroid differentiation model by establishing induced pluripotent stem cel
Externí odkaz:
https://doaj.org/article/9fedb1fd15bb4f8386a7236b9bbe1f02
Autor:
Gwendoline Lozachmeur, Aude Bramoulle, Antoine Aubert, François Stüder, Julien Moehlin, Lucie Madrange, Frank Yates, Jean-Philippe Deslys, Marco Antonio Mendoza-Parra
Spatially-resolved transcriptomics is revolutionizing our understanding of complex tissues, but their current use for the exploration of a few sections is not representative of their 3-dimensional architecture. In this work we present a low-cost stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da4e994f90a9e45be50e1c5d4bce046e
https://doi.org/10.1101/2023.01.18.524520
https://doi.org/10.1101/2023.01.18.524520
Autor:
Manon Leclercq, Isciane Commenge, Marylou Bouriot, Floricia Crusset, Patrick Gonzalez, Julien Grimaud, Frank Yates, Jacqueline Sarfati-Bert, Agnès Saint-Pol
Aspergillosis is a nosocomial disease that usually affects the respiratory system. While most patients develop mild symptoms, aspergillosis can become a serious health threat in immunocompromised populations and patients with pre-existing respiratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13195b56a2f425479d87c19a92e5538c
https://doi.org/10.1101/2022.03.24.485625
https://doi.org/10.1101/2022.03.24.485625