Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Frank W. Perrella"'
Autor:
Anthony A. Gaspari, Frank W. Perrella
Publikováno v:
Methods. 27:77-86
Natural rubber latex (NRL), derived from the Hevea brasiliensis tree, is a material used to manufacture products in health care, including medical gloves. Proteins are a naturally occurring component of NRL. These proteins, which can be present on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c3efd4f5fe1557fc98338a66c223df
https://doi.org/10.1016/s1046-2023(02)00055-5
https://doi.org/10.1016/s1046-2023(02)00055-5
Publikováno v:
Journal of Medicinal Chemistry. 37:2232-2237
A series of nitrocoumarin and nitrochromene derivatives have been prepared and shown to inhibit the phosphatidylinositol-specific phospholipase C(PLC)(IC50 < 10 micrograms/mL) isolated from human melanoma. The inhibition of PLC by nitrocoumarin 4a wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e48d3c71af7b89aa097391312eec1427
https://doi.org/10.1021/jm00040a016
https://doi.org/10.1021/jm00040a016
Publikováno v:
ChemInform. 25
A series of nitrocoumarin and nitrochromene derivatives have been prepared and shown to inhibit the phosphatidylinositol-specific phospholipase C(PLC)(IC50 < 10 micrograms/mL) isolated from human melanoma. The inhibition of PLC by nitrocoumarin 4a wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d243eb1453b826a3eec99003e10d14
https://doi.org/10.1002/chin.199448154
https://doi.org/10.1002/chin.199448154
Autor:
Robert F. Kaltenbach, Josepg C. Calabrese, Remko H. Vreekamp, Steven P. Seitz, Frank W. Perrella
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 2:171-174
The preparation of a phosphatidylinositol analog lacking the axial 2-hydroxyl of the inositol ring is described. The compound is a usefulk mecanistic probe for the phosphatidylinositol specifc phospholipase C.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b67833245f6679051788b3fc5693db7
https://doi.org/10.1016/s0960-894x(01)80444-3
https://doi.org/10.1016/s0960-894x(01)80444-3
Autor:
Gurrinder S. Bedi, Robert P. Burns, Anthony A. Gaspari, Thomas H. Thatcher, Carol Tanck, Frank W. Perrella, Barbara Ferbel
Publikováno v:
Clinical immunology (Orlando, Fla.). 105(1)
The purpose of the present investigation was to determine whether enzyme-treated (ET)-NRL is less immunogenic than untreated NRL in a BALB/c mouse model of primary in vivo sensitization following repeated subcutaneous injections with the aqueous phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9390d945aaa2c6b5cf8f3a6a1c7a880
https://pubmed.ncbi.nlm.nih.gov/12483989
https://pubmed.ncbi.nlm.nih.gov/12483989
Autor:
Frank W. Perrella
Publikováno v:
Biochemical and biophysical research communications. 166(2)
Phosphoinositide phospholipase C activity was investigated in human melanoma grown as solid tumor xenografts in nude mice. The enzyme was dependent on calcium for activity and was stimulated by the detergent deoxycholate. The pH optimum was 5.5 in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d74678097140743ecedaff68574d481
https://pubmed.ncbi.nlm.nih.gov/2302236
https://pubmed.ncbi.nlm.nih.gov/2302236
Autor:
Frank W. Perrella
Publikováno v:
Journal of Occupational & Environmental Medicine. 38:423
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34e4aadfcf74aefdf258fac560ee93d8
https://doi.org/10.1097/00043764-199604000-00057
https://doi.org/10.1097/00043764-199604000-00057
Autor:
Frank W. Perrella
Publikováno v:
Analytical Biochemistry. 174:437-447
EZ-FIT, an interactive microcomputer software package, has been developed for the analysis of enzyme kinetic and equilibrium binding data. EZ-FIT was designed as a user-friendly menu-driven package that has the facility for data entry, editing, and f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e6f031bad500f9f9307574dd6d2e51
https://doi.org/10.1016/0003-2697(88)90042-5
https://doi.org/10.1016/0003-2697(88)90042-5
Autor:
Michael A. Lea, Frank W. Perrella
Publikováno v:
Biochemical and Biophysical Research Communications. 82:575-581
Purified rat liver nuclei were incubated in vitro with [3H]NAD. Altered patterns of ADP-ribosylation of nuclear proteins occurred with 1 mM spermidine or spermine with the latter polyamine causing the greater change. Spermine treated nuclei showed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a99bed82c8e10285714db7e323d411
https://doi.org/10.1016/0006-291x(78)90913-0
https://doi.org/10.1016/0006-291x(78)90913-0
Autor:
Frank W. Perrella, R.K. Boutwell
Publikováno v:
Cancer Letters. 21:37-41
The dorsal skin of female CD-1 mice was treated with triethylenemelamine (TEM) to determine whether this agent acted either as a complete carcinogen or as an initiator of carcinogenesis. A dose of 0.01-1.0 mumol of TEM applied once a week for 32 week
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce76f58daac81c13b79daefe02e8670
https://doi.org/10.1016/0304-3835(83)90080-0
https://doi.org/10.1016/0304-3835(83)90080-0