Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Frank W. Crow"'
Autor:
Takakazu Matsushita, Toshikazu Yagi, Joseph A. Hardin, Jennifer D. Cragun, Frank W. Crow, H. Robert Bergen, Gregory J. Gores, Scott L. Nyberg M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 12 (2003)
We have previously shown that cryopreservation leads to increased apoptotic death of porcine hepatocytes intended for use in a bioartificial liver (BAL). This study was designed to determine if a broad-spectrum caspase inhibitor, IDN–1965, reduced
Externí odkaz:
https://doaj.org/article/252717a4f37b445ca7bb71e381becc75
Autor:
Manuel Posada de la Paz, Kenneth L. Johnson, Stephen Naylor, Frank W. Crow, Jennifer D. Cragun, Maria Victoria Ruiz
Publikováno v:
Biomedical Chromatography. 16:311-318
An integrated differential approach to the characterization of complex mixtures is presented which includes the targeting of liquid chromatography (LC) peaks for identification using characteristic UV adsorption of the LC peak, subsequent molecular w
Publikováno v:
Analytical Biochemistry. 298:32-39
The presence of senile plaques composed of amyloid-beta (Abeta) polypeptides within brain tissue is normally used as a definitive postmortem diagnosis for Alzheimer's Disease (AD). Therefore, these polypeptides have been investigated as potential bio
Autor:
Thomas J. Thamann, Wayne K. Duholke, Brian D. Kaluzny, Russell H. Robins, Jane E. Guido, Bruce A. Pearlman, Frank W. Crow, Chad E. Hadden, Gary E. Martin
Publikováno v:
Journal of Heterocyclic Chemistry. 36:1107-1114
TipranavirTM (PNU-140690) is a protease inhibitor under clinical investigation for the treatment of human acquired immunodeficiency syndrome (AIDS). During scale-up synthesis of clinical quantities of the bulk drug, a colored, transient by-product of
Autor:
Constance G. Chidestere, James R. Blinn, John W. Hallberg, Anne M. Cooper, Wayne K. Duholke, Frank W. Crow, Richard F. Smith, Gary E. Martin, Thomas J. Thamann
Publikováno v:
Journal of Heterocyclic Chemistry. 36:1049-1055
The structure of a novel, thermally-induced degradant of the antibiotic pirlimycin is presented. The degradant was discovered during thermal stress stability testing of pirlimycin. The structure was determined using high resolution mass spectrometry,
Autor:
Chad E. Hadden, Frank W. Crow, David A. Hahn, Richard F. Smith, Christopher S. Mallory, Kathleen A. Farley, Gary E. Martin, Thomas J. Thamann, Brian D. Kaluzny, Wayne K. Duholke
Publikováno v:
Journal of Heterocyclic Chemistry. 36:365-370
The rigorous structural characterization of novobiocin, is reported using mass spectrometric, infrared and nmr spectroscopic analysis. Complete nmr assignments are reported. Previous reports in the literature had left some quaternary carbon resonance
Autor:
Ward Lutz, Frank W. Crow, John C. Lieske, Nikolina Babic, Rajiv Kumar, Timothy S. Larson, Ravinder J. Singh
Publikováno v:
Clinical Chemistry. 53:540-542
Recent studies suggest that microalbuminuria confers increased cardiovascular risk, even in nondiabetic and nonhypertensive persons (1)(2). Clinically, the testing of microalbuminuria uses immunochemical methods. Controversy exists, however, regardin
Autor:
Brian D. Kaluzny, J. Gordon Marr, Frank W. Crow, Gary E. Martin, Terry J. Gilbertson, Gwendolyn D. Fate
Publikováno v:
Magnetic Resonance in Chemistry. 36:635-644
Early efforts to utilize 15N NMR spectroscopy in structure elucidation studies were often frustrated by the low gyromagnetic ratio (γN) and the low natural abundance (0.37%) of the nuclide. The advent of 1H and inverse-detected 2D NMR methods has el
Autor:
Thomas J. Thamann, Jane E. Guido, Bowman Phil B, Kathleen A. Farley, Frank W. Crow, Brenda S. Vonderwell, Russell H. Robins, Gary E. Martin, Richard F. Smith, Wayne K. Duholke, Sandra M. Sims, Jay C. Brumfield
Publikováno v:
Magnetic Resonance in Chemistry. 36:S11-S16
A method is described for unequivocally establishing the site of N-oxidation which relies on the relatively large downfield shift of aliphatic nitrogen resonances following oxidation. The technique described is based on 15N at natural abundance and d
Autor:
Frank W. Crow, et al. et al.
Publikováno v:
ChemInform. 30