Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Frank Van Vynckt"'
Autor:
Florence Lefranc, Tine Mahieu, Jean-François Gaussin, Mohamed El Yazidi, Sébastien Sauvage, Jerome Tuti, Janique Dewelle, Tatjana Mijatovic, Robert Kiss, Francis Darro, Fabrice Ribaucour, Eric Van Quaquebeke, Gentiane Simon, Patrick Dumont, Frank Van Vynckt
Publikováno v:
Journal of Medicinal Chemistry. 50:4122-4134
Amonafide (1), a naphthalimide which binds to DNA by intercalation and poisons topoisomerase IIalpha, has demonstrated activity in phase II breast cancer trials, but has failed thus far to enter clinical phase III because of dose-limiting bone marrow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c38f4299aaccb6644f857048f70a3ca
https://doi.org/10.1021/jm070315q
https://doi.org/10.1021/jm070315q
Autor:
Eric Van Quaquebeke, Florence Lefranc, Frank Van Vynckt, Francis Darro, Robert Kiss, Tatjana Mijatovic
Publikováno v:
Drug Development Research. 68:164-173
Several reports suggest the sodium pump as an interesting oncology target, given that its subunit expression is markedly altered in cancer. By binding to the sodium pump, cardiotonic steroids, notably cardenolides, the natural high-affinity Na+/K+-AT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55a8e6f1e60fc38a49f887f9a86a131e
https://doi.org/10.1002/ddr.20178
https://doi.org/10.1002/ddr.20178
Autor:
Eric Van Quaquebeke, Tine Mahieu, Patrick Dumont, Janique Dewelle, Fabrice Ribaucour, Gentiane Simon, Sébastien Sauvage, Jean-François Gaussin, Jérôme Tuti, Mohamed El Yazidi, Frank Van Vynckt, Tatjana Mijatovic, Florence Lefranc, Francis Darro, Robert Kiss
Publikováno v:
Journal of Medicinal Chemistry; Aug2007, Vol. 50 Issue 17, p4122-4134, 13p