Zobrazeno 1 - 10
of 6 059
pro vyhledávání: '"Frank V"'
Autor:
Charles Lu, Mehmet Altan, Apar Pataer, Tina Cascone, Annikka Weissferdt, Jianjun Zhang, Boris Sepesi, Ara A Vaporciyan, Marcelo V Negrao, Hai T Tran, Stephen G Swisher, John V Heymach, Don L Gibbons, Brett W Carter, Jack A Roth, Ferdinandos Skoulidis, Yasir Y Elamin, Xiuning Le, Wayne L Hofstetter, J Jack Lee, Bonnie S Glisson, Myrna C B Godoy, Garrett L Walsh, Jia Wu, Humam Kadara, George R Blumenschein, Heather Y Lin, Nicolas Zhou, William N William, Cheuk H Leung, Frank V Fossella, Anne S Tsao, Jonathan M Kurie, Lauren A Byers, Reza J Mehran, David C Rice, Luisa M Solis Soto
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 10 (2024)
Background Neoadjuvant immune checkpoint inhibitors (ICIs) have improved survival outcomes compared with chemotherapy in resectable non-small cell lung cancer (NSCLC). However, the impact of actionable genomic alterations (AGAs) on the efficacy of ne
Externí odkaz:
https://doaj.org/article/6cabe896ecc5458b81684d743e2ba8f9
Publikováno v:
eLife, Vol 13 (2024)
The M2 proton channel aids in the exit of mature influenza viral particles from the host plasma membrane through its ability to stabilize regions of high negative Gaussian curvature (NGC) that occur at the neck of budding virions. The channels are ho
Externí odkaz:
https://doaj.org/article/efb4eda96df24223966e432ad190dc28
Publikováno v:
Physiological Reports, Vol 12, Iss 16, Pp n/a-n/a (2024)
Abstract Aging is associated with cardiac contractile abnormalities, but the etiology of these contractile deficits is unclear. We hypothesized that cardiac contractile and regulatory protein expression is altered during aging. To investigate this po
Externí odkaz:
https://doaj.org/article/f577a9b7cdf84a6c8ed5051c85411fc2
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Introduction: Vasodilatation in response to NO is a fundamental response of the vasculature, and during aging, the vasculature is characterized by an increase in stiffness and decrease in sensitivity to NO mediated vasodilatation. Vascular tone is re
Externí odkaz:
https://doaj.org/article/15a795b98918469b9b56d5e82132cc86
Autor:
Stewart W Mercer, Clare MacRae, Steven Lin, David Loxterkamp, William B Ventres, Leslie A Stone, Lauren E Gibson-Oliver, Elizabeth Kyle Meehan, Mari A Ricker, Stacy A Ogbeide, Frank V deGruy, Megan R Mahoney
Publikováno v:
Family Medicine and Community Health, Vol 12, Iss Suppl 3 (2024)
Externí odkaz:
https://doaj.org/article/33f975b52ff84bbab23f6bbc518cff49
Autor:
Frank V. Kowalski
Publikováno v:
AIP Advances, Vol 14, Iss 3, Pp 035154-035154-7 (2024)
The decay of the electrical energy in a resistor-vacuum capacitor circuit is shown to involve multiple relaxation processes, with dramatically different time constants. This is measured using a vacuum capacitor to eliminate the effect of a dielectric
Externí odkaz:
https://doaj.org/article/abc3752b21ec4dd09ab55a207a653084
Autor:
Farha Khan, Matthias Elgeti, Samuel Grandfield, Aviv Paz, Fiona B. Naughton, Frank V. Marcoline, Thorsten Althoff, Natalia Ermolova, Ernest M. Wright, Wayne L. Hubbell, Michael Grabe, Jeff Abramson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Sodium-dependent glucose transporters (SGLTs) couple a downhill Na+ ion gradient to actively transport sugars. Here, we investigate the impact of the membrane potential on vSGLT structure and function using sugar uptake assays, double electr
Externí odkaz:
https://doaj.org/article/14990935ce0547d8bbd11e73b798bc03
Autor:
Kaiwen Wang, PharmD, Robyn Du, BS, Sinchita Roy-Chowdhuri, MD, Ziping T. Li, MD, Lingzhi Hong, MD, Natalie Vokes, MD, Yasir Y. Elamin, MD, Celyne Bueno Hume, MD, Ferdinandos Skoulidis, MD, PhD, Carl M. Gay, MD, PhD, George Blumenschein, MD, Frank V. Fossella, MD, Anne Tsao, MD, Jianjun Zhang, MD, PhD, Niki Karachaliou, MD, Aurora O’Brate, PhD, Claudia-Nanette Gann, MD, Jeff Lewis, MS, Waree Rinsurongkawong, PhD, J. Jack Lee, PhD, MS, DDS, Don Lynn Gibbons, MD, PhD, Ara A. Vaporciyan, MD, John V. Heymach, MD, PhD, Mehmet Altan, MD, Xiuning Le, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 8, Pp 100533- (2023)
Introduction: MET amplification is a known resistance mechanism to EGFR tyrosine kinase inhibitor (TKI) treatment in EGFR-mutant NSCLC. Dual EGFR-MET inhibition has been reported with success in overcoming such resistance and inducing clinical benefi
Externí odkaz:
https://doaj.org/article/abe6440483814bd08d4c9b73ab459684
Autor:
Mehmet Yildiz, Michael D. Miedema, Avinash Murthy, Timothy D. Henry, Seth Bergstedt, Brynn K. Okeson, Christian W. Schmidt, Lucas Volpenhein, Santiago Garcia, Scott W. Sharkey, Frank V. Aguirre
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e17308- (2023)
Although there is an established association between elevated triglyceride (eTG, ≥175 mg/dl) levels and adverse cardiovascular events, some studies have suggested that eTG levels may be linked to neutral or even improved clinical outcomes, particul
Externí odkaz:
https://doaj.org/article/8d51b19265574a2eba8e64daa1a0edd0
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 3, Pp 290-301 (2022)
Abstract Berkeley Madonna is a software program that provides an easy and intuitive environment for graphically building and numerically solving mathematical equations. Our users range from college undergraduates with little or no mathematical experi
Externí odkaz:
https://doaj.org/article/5018cc470fe34bf88834b6ab167b94d6