Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Frank Tippmann"'
Autor:
Lars Lilge, Alexander Reder, Frank Tippmann, Friedrich Morgenroth, Janice Grohmann, Dörte Becher, Katharina Riedel, Uwe Völker, Michael Hecker, Ulf Gerth
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Regulated ATP-dependent proteolysis is a common feature of developmental processes and plays also a crucial role during environmental perturbations such as stress and starvation. The Bacillus subtilis MgsR regulator controls a subregulon within the s
Externí odkaz:
https://doaj.org/article/f1d90af889a64a239cb65e81f5e11733
Autor:
Lena Eismann, Igor Fijalkowski, Carla Verónica Galmozzi, Jiří Koubek, Frank Tippmann, Petra Van Damme, Günter Kramer
Publikováno v:
CELL REPORTS
The chaperone SecB has been implicated in de novo protein folding and translocation across the membrane, but it remains unclear which nascent polypeptides SecB binds, when during translation SecB acts, how SecB function is coordinated with other chap
Autor:
Josef J. Auburger, Ilia Kats, Frank Tippmann, Bernd Bukau, Jaro Schmitt, Günter Kramer, Sander J. Tans, Matilde Bertolini, Kai Fenzl, Florian Wruck
Publikováno v:
Science, 371(6524)
Science
Science
Co-co assembly for oligomers Most of the human proteome forms oligomeric protein complexes, but how they assemble is poorly understood. Bertolini et al. used a ribosome-profiling approach to explore the existence of a cotranslational assembly mode ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c68b6e47c68fa665c3cb018edc0440
http://resolver.tudelft.nl/uuid:b6aba24a-d6f3-4774-97bb-d6e150a1a16a
http://resolver.tudelft.nl/uuid:b6aba24a-d6f3-4774-97bb-d6e150a1a16a
Autor:
Günter Kramer, Kevin Klann, Bernd Bukau, Frank Tippmann, Kristina Döring, Ulrike A. Friedrich, Ayala Shiber, Mostafa Zedan, Dorina Merker
Publikováno v:
Nature
The folding of newly synthesized proteins to the native state is a major challenge within the crowded cellular environment, as non-productive interactions can lead to misfolding, aggregation and degradation1. Cells cope with this challenge by couplin
Publikováno v:
The FASEB Journal. 23:1643-1654
Late-onset Alzheimer's disease is often connected with nutritional misbalance, such as enhanced cholesterol intake, deficiency in polyunsaturated fatty acids, or hypovitaminosis. The alpha-secretase ADAM10 has been found to be regulated by retinoic a
Publikováno v:
Neurodegenerative Diseases. 7:190-192
Background: In the past, we demonstrated that the disintegrin metalloproteinase ADAM10 has α-secretase activity in vitro and in cultured cells. We also found out that moderate overexpression of this proteinase inhibits Aβ peptide production and pre
Autor:
Frank Tippmann, Clara Theunis, Falk Fahrenholz, Fred Van Leuven, Elzbieta Kojro, Ilse Dewachter, Ewa Wieczerzak, Dorothea Rat, Ulrich Schmitt, Rolf Postina
Publikováno v:
The FASEB Journal
Article
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, no.9, p. 3208-18 (2011)
Article
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, no.9, p. 3208-18 (2011)
Pituitary adenylate cyclase-activating polypeptide (PACAP) has neuroprotective and neurotrophic properties and is a potent alpha-secretase activator. As PACAP peptides and their specific receptor PAC1 are localized in central nervous system areas aff
Publikováno v:
Magnetic resonance in medicine. 57(4)
Different strategies to visualize amyloid plaques with MRI at 17.6 Tesla were investigated in a novel mouse model of Alzheimer's disease (AD). Large iron-containing plaques were observed in the thalamus, but cortical plaques did not show iron deposit
Autor:
Lilge, Lars, Reder, Alexander, Tippmann, Frank, Morgenroth, Friedrich, Grohmann, Janice, Becher, Dörte, Riedel, Katharina, Völker, Uwe, Hecker, Michael, Gerth, Ulf
Publikováno v:
Frontiers in Microbiology; 5/12/2020, Vol. 11, p1-14, 14p
Autor:
Shiber, Ayala, Döring, Kristina, Friedrich, Ulrike, Klann, Kevin, Merker, Dorina, Zedan, Mostafa, Tippmann, Frank, Kramer, Günter, Bukau, Bernd
Publikováno v:
Nature; Sep2018, Vol. 561 Issue 7722, p268-272, 5p, 2 Diagrams, 2 Charts, 10 Graphs