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Autor:
Babs G. Taal, Barbara M. Loftus, Frank Telleman, Godefridus J. Peters, Patrick G. Johnston, G. Wynne Aherne, Frans A. N. Zoetmulder, Cornelius J. van Groeningen, Herbert M. Pinedo, Pascale Schoenmakers, Thea Tadema, Baukelien van Triest, H. H. J. Backus
Publikováno v:
Journal of Histochemistry & Cytochemistry. 48:755-760
Colorectal cancer is one of the most common human cancers, for which 5-fluorouracil (5FU) is usually part of the treatment. Thymidylate synthase (TS), the target enzyme for 5FU, can be predictive for the outcome of 5FU-based therapy. TS levels in tum