Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Frank Telang"'
Autor:
Jean Logan, Sung Won Kim, Deborah Pareto, Frank Telang, Gene-Jack Wang, Joanna S. Fowler, Anat Biegon
Publikováno v:
Molecular Imaging, Vol 13 (2014)
Using positron emission tomography, we investigated the kinetics of [ 11 C]vorozole ([ 11 C]VOR), a radiotracer for the enzyme aromatase that catalyzes the last step in estrogen biosynthesis. Six subjects were scanned under baseline conditions follow
Externí odkaz:
https://doaj.org/article/c5b78b1367314174b41ae71030da65aa
Autor:
Nora D Volkow, Dardo Tomasi, Gene-Jack Wang, Frank Telang, Joanna S Fowler, Rita Z Goldstein, Nelly Klein, Christopher Wong, James M Swanson, Elena Shumay
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63492 (2013)
Aging is associated with reductions in brain glucose metabolism in some cortical and subcortical regions, but the rate of decrease varies significantly between individuals, likely reflecting genetic and environmental factors and their interactions. H
Externí odkaz:
https://doaj.org/article/1c07d6d5e0c64d6395cec62b859b7b67
Autor:
Gene-Jack Wang, Nora D Volkow, Timothy Wigal, Scott H Kollins, Jeffrey H Newcorn, Frank Telang, Jean Logan, Millard Jayne, Christopher T Wong, Hao Han, Joanna S Fowler, Wei Zhu, James M Swanson
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63023 (2013)
Brain dopamine dysfunction in attention deficit/hyperactivity disorder (ADHD) could explain why stimulant medications, which increase dopamine signaling, are therapeutically beneficial. However while the acute increases in dopamine induced by stimula
Externí odkaz:
https://doaj.org/article/e06c83766b56482eb14d27df01da9b4b
Autor:
Nora D Volkow, Dardo Tomasi, Gene-Jack Wang, Joanna S Fowler, Frank Telang, Rita Z Goldstein, Nelly Alia-Klein, Christopher Wong
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16573 (2011)
Gender differences in vulnerability for cocaine addiction have been reported. Though the mechanisms are not understood, here we hypothesize that gender differences in reactivity to conditioned-cues, which contributes to relapse, are involved.To test
Externí odkaz:
https://doaj.org/article/50117073963e4cd2a37b5b962e832667
Autor:
Nora D Volkow, Joanna S Fowler, Gene-Jack Wang, Elena Shumay, Frank Telang, Peter K Thanos, David Alexoff
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15269 (2010)
Methamphetamine is one of the most toxic of the drugs of abuse, which may reflect its distribution and accumulation in the body. However no studies have measured methamphetamine's organ distribution in the human body.Positron Emission Tomography (PET
Externí odkaz:
https://doaj.org/article/ba02bd0438134c7ba1bc754950ba4f41
Autor:
Nora D Volkow, Gene-Jack Wang, Dardo Tomasi, Frank Telang, Joanna S Fowler, Kith Pradhan, Millard Jayne, Jean Logan, Rita Z Goldstein, Nelly Alia-Klein, Christopher Wong
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11509 (2010)
Dopamine (phasic release) is implicated in conditioned responses. Imaging studies in cocaine abusers show decreases in striatal dopamine levels, which we hypothesize may enhance conditioned responses since tonic dopamine levels modulate phasic dopami
Externí odkaz:
https://doaj.org/article/054edb16b3354dada383158d525195c3
Autor:
Dardo Tomasi, Nora D Volkow, Ruiliang Wang, Jean H Carrillo, Thomas Maloney, Nelly Alia-Klein, Patricia A Woicik, Frank Telang, Rita Z Goldstein
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10815 (2010)
Chronic cocaine use is associated with disrupted dopaminergic neurotransmission but how this disruption affects overall brain function (other than reward/motivation) is yet to be fully investigated. Here we test the hypothesis that cocaine addicted s
Externí odkaz:
https://doaj.org/article/cde5693dc2de4a739c98932d6d769e5d
Autor:
Dardo Tomasi, Gene-Jack Wang, Ruiliang Wang, Walter Backus, Allan Geliebter, Frank Telang, Millar C Jayne, Christopher Wong, Joanna S Fowler, Nora D Volkow
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6847 (2009)
BACKGROUND:Gastric distention (GD), as it occurs during meal ingestion, signals a full stomach and it is one of the key mechanisms controlling food intake. Previous studies on GD showed lower activation of the amygdala for subjects with higher body m
Externí odkaz:
https://doaj.org/article/5c3cb7971cc4499fbff8d374e69e071a
Autor:
Dardo Tomasi, Nora D Volkow, Ruiliang Wang, Frank Telang, Gene-Jack Wang, Linda Chang, Thomas Ernst, Joanna S Fowler
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e6102 (2009)
BACKGROUND:Dopamine and dopamine transporters (DAT, which regulate extracellular dopamine in the brain) are implicated in the modulation of attention but their specific roles are not well understood. Here we hypothesized that dopamine modulates atten
Externí odkaz:
https://doaj.org/article/3e3fdd379e1c40319762dd2e64901b56
Autor:
Nora D Volkow, Joanna S Fowler, Gene-Jack Wang, Frank Telang, Jean Logan, Christopher Wong, Jim Ma, Kith Pradhan, Helene Benveniste, James M Swanson
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e2017 (2008)
The use of stimulants (methylphenidate and amphetamine) as cognitive enhancers by the general public is increasing and is controversial. It is still unclear how they work or why they improve performance in some individuals but impair it in others. To
Externí odkaz:
https://doaj.org/article/3597a4a8dfbe4b308033f03f676c9517