Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Frank S Choveau"'
Autor:
Frank S. Choveau, Ismail Ben Soussia, Delphine Bichet, Franck C. Chatelain, Sylvain Feliciangeli, Florian Lesage
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/891b8670092a439983df64c08e0023d9
Autor:
Frank S Choveau, Ismail Ben Soussia, Delphine Bichet, Chatelain C. Franck, Sylvain Feliciangeli, Florian Lesage
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Inhibitory potassium channels of the TREK1/TRAAK family are integrators of multiple stimuli, including temperature, membrane stretch, polyunsaturated fatty acids and pH. How these signals affect the gating of these channels is the subject of intense
Externí odkaz:
https://doaj.org/article/07d33a38848c4d0183ced9c73c1ad2aa
Publikováno v:
Biomedicines, Vol 8, Iss 8, p 251 (2020)
Adrenocortical carcinoma (ACC) presents a high risk of relapse and metastases with outcomes not improving despite extensive research and new targeted therapies. We recently showed that the Hedgehog receptor Patched is expressed in ACC, where it stron
Externí odkaz:
https://doaj.org/article/95c3ebc4b32a43f4890c866c3f3575ac
Autor:
Ismail Ben Soussia, Frank S. Choveau, Sandy Blin, Eun-Jin Kim, Sylvain Feliciangeli, Franck C. Chatelain, Dawon Kang, Delphine Bichet, Florian Lesage
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
TREK/TRAAK channels are polymodal K+ channels that convert very diverse stimuli, including bioactive lipids, mechanical stretch and temperature, into electrical signals. The nature of the structural changes that regulate their activity remains an ope
Externí odkaz:
https://doaj.org/article/67683d0d8ef84390be2c9f1f6e496be8
Autor:
Sylvain Feliciangeli, Frank S. Choveau, Florian Lesage, Delphine Bichet, Ismail Ben Soussia, Franck C. Chatelain
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145367 (2015)
In the central and peripheral nervous system, the assembly of KCNQ3 with KCNQ2 as mostly heteromers, but also homomers, underlies "M-type" currents, a slowly-activating voltage-gated K+ current that plays a dominant role in neuronal excitability. KCN
Externí odkaz:
https://doaj.org/article/22a2692ee5404606a8d3c0b3b924b701
Autor:
Ismail Ben Soussia, Chatelain C Franck, Florian Lesage, Frank S. Choveau, Sylvain Feliciangeli, Delphine Bichet
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Frontiers, 2021, 12, ⟨10.3389/fphar.2021.755826⟩
Frontiers in Pharmacology, Frontiers, 2021, 12, pp.755826. ⟨10.3389/fphar.2021.755826⟩
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology, Frontiers, 2021, 12, ⟨10.3389/fphar.2021.755826⟩
Frontiers in Pharmacology, Frontiers, 2021, 12, pp.755826. ⟨10.3389/fphar.2021.755826⟩
Frontiers in Pharmacology, Vol 12 (2021)
International audience; Inhibitory potassium channels of the TREK1/TRAAK family are integrators of multiple stimuli, including temperature, membrane stretch, polyunsaturated fatty acids and pH. How these signals affect the gating of these channels is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c09d12df5f13270474b1eac153037f
https://hal.archives-ouvertes.fr/hal-03440192
https://hal.archives-ouvertes.fr/hal-03440192
Autor:
Frank S Choveau, Fayal eAbderemane-Ali, Fabien C Coyan, Zeineb eEs-Salah-Lamoureux, Isabelle eBaro, Gildas eLoussouarn
Publikováno v:
Frontiers in Pharmacology, Vol 3 (2012)
Voltage-gated potassium (Kv) channels are tetramers, each subunit presenting six transmembrane segments (S1-S6), with each S1-S4 segments forming a voltage-sensing domain (VSD) and the four S5-S6 forming both the conduction pathway and its gate. S4 s
Externí odkaz:
https://doaj.org/article/905354626e3f4895b355789880175805
Publikováno v:
Journal of Biological Chemistry. 293:19411-19428
Phosphatidylinositol 4,5-bisphosphate (PIP2) in the plasma membrane regulates the function of many ion channels, including M-type (potassium voltage-gated channel subfamily Q member (KCNQ), Kv7) K+ channels; however, the molecular mechanisms involved
Publikováno v:
Neuron. 92:461-478
The fidelity of neuronal signaling requires organization of signaling molecules into macromolecular complexes, whose components are in intimate proximity. The intrinsic diffraction limit of light makes visualization of individual signaling complexes