Data from Mitochondrial BAX Determines the Predisposition to Apoptosis in Human AML

Autor: Frank Edlich, Florian Heidel, Jens U. Marquardt, Konstanze Döhner, Denise Wolleschak, Franziska Todt, Peter Scholz-Kreisel, Kathrin Funk, Diana Becker, Enrico Schalk, Cornelius Wiedenmann, Frank Reichenbach

Purpose: Cell-to-cell variability in apoptosis signaling contributes to heterogenic responses to cytotoxic stress in clinically heterogeneous neoplasia, such as acute myeloid leukemia (AML). The BCL-2 proteins BAX and BAK can commit mammalian cells t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2795b7d30f8c705ca2f7b2a38702db33
https://doi.org/10.1158/1078-0432.c.6525251

Retrospective Analysis of Treatment Pathways in Patients With BRAF

Autor: Armin, Gerger, Wolfgang, Eisterer, Stefan, Fuxius, Sara, Bastian, Dieter, Koeberle, Manfred, Welslau, Dilara Akhoundova, Sanoyan, Christian, Maas, Jens, Uhlig, Klaus, Fenchel, Richard, Greil, Eyck, VON DER Heyde, Gaëlle Rhyner, Agocs, Rudolf, Weide, Monika, Schwager, Frank, Reichenbach, Dominik Paul, Modest, Ralph, Fritsch

Publikováno v: Anticancer research. 42(10)

Metastatic colorectal cancer (mCRC) is a heterogeneous disease with distinct molecular subtypes. The BRAFAnonymized data from BRAFForty-two patients were eligible for analysis (mean age 62.1 years, 47.6% female). At initial diagnosis, 20 patients (47

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cf2e38d8741f3688ddbfaef478162e71
https://pubmed.ncbi.nlm.nih.gov/36191968

Retrospective Analysis of Treatment Pathways in Patients With BRAFV600E-mutant Metastatic Colorectal Carcinoma - MORSECRC

Autor: ARMIN GERGER, WOLFGANG EISTERER, STEFAN FUXIUS, SARA BASTIAN, DIETER KOEBERLE, MANFRED WELSLAU, DILARA AKHOUNDOVA SANOYAN, CHRISTIAN MAAS, JENS UHLIG, KLAUS FENCHEL, RICHARD GREIL, EYCK VON DER HEYDE, GAËLLE RHYNER AGOCS, RUDOLF WEIDE, MONIKA SCHWAGER, FRANK REICHENBACH, DOMINIK PAUL MODEST, RALPH FRITSCH

Publikováno v: Gerger, Armin; Eisterer, Wolfgang; Fuxius, Stefan; Bastian, Sara; Koeberle, Dieter; Welslau, Manfred; Akhoundova Sanoyan, Dilara; Maas, Christian; Uhlig, Jens; Fenchel, Klaus; Greil, Richard; von der Heyde, Eyck; Rhyner Agocs, Gaëlle; Weide, Rudolf; Schwager, Monika; Reichenbach, Frank; Modest, Dominik Paul; Fritsch, Ralph (2022). Retrospective Analysis of Treatment Pathways in Patients With BRAFV600E-mutant Metastatic Colorectal Carcinoma-MORSECRC. Anticancer research, 42(10), pp. 4773-4785. International Inst. of Anticancer Research 10.21873/anticanres.15982

BACKGROUND/AIM Metastatic colorectal cancer (mCRC) is a heterogeneous disease with distinct molecular subtypes. The BRAFV600E-mutation found in approximately 8-12% of mCRC patients is associated with poor prognosis. Guideline recommendations for this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2790dec295899d86fd9bcfece5d03e6f

The relevance of mitochondrial BAX re-distribution for apoptotic evasion in human hepatocellular carcinoma

Autor: Frank Edlich, Kathrin Funk, D Becker, Carolin Czauderna, Frank Reichenbach, J Hajduk, Jens U. Marquardt, PR Galle

Publikováno v: Zeitschrift für Gastroenterologie.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85e8038b3d024948dfc7f3452619b391
https://doi.org/10.1055/s-0039-3402236

Evaluation of a Mobile Phone App for Patients With Pollen-Related Allergic Rhinitis: Prospective Longitudinal Field Study

Autor: Robin Anger, Manuela Glattacker, Adrian Tassoni, Juergen M Giesler, Martin Boeker, Rainer Bredenkamp, Frank Reichenbach

Publikováno v: JMIR mHealth and uHealth
JMIR mHealth and uHealth, Vol 8, Iss 4, p e15514 (2020)

Background Mobile health apps have great potential to support the self-management of chronic conditions such as allergic diseases, which constitute significant challenges in health care. However, the health app market is confusing for users, as it is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e9b6a2d44ac54ce9fd4f7931cd70cd
https://pubmed.ncbi.nlm.nih.gov/32301735