Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Frank Radecke"'
Autor:
Anna Osiak, Frank Radecke, Eva Guhl, Sarah Radecke, Nadine Dannemann, Fabienne Lütge, Silke Glage, Cornelia Rudolph, Tobias Cantz, Klaus Schwarz, Regine Heilbronn, Toni Cathomen
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28911 (2011)
Gene knockout in murine embryonic stem cells (ESCs) has been an invaluable tool to study gene function in vitro or to generate animal models with altered phenotypes. Gene targeting using standard techniques, however, is rather inefficient and typical
Externí odkaz:
https://doaj.org/article/368166d969e343d6b3056ac64ca6a795
Short single-stranded oligodeoxynucleotides are versatile molecular tools used in different applications. They enable gene repair and genome editing, and they are central to the antisense technology. Because the usability of single-stranded oligodeox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d159a1166f545efa66d368133f90de95
https://europepmc.org/articles/PMC5763015/
https://europepmc.org/articles/PMC5763015/
Publikováno v:
HLA. 92:233-234
Long nanopore reads allow phasing of heterozygous positions but show limitations in sequencing of homopolymers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fefeab5b9dc4ab939e5ed6189995855
https://doi.org/10.1111/tan.13360
https://doi.org/10.1111/tan.13360
Publikováno v:
Molecular Therapy. 18(4):743-753
Correcting a mutated gene directly at its endogenous locus represents an alternative to gene therapy protocols based on viral vectors with their risk of insertional mutagenesis. When solely a single-stranded oligodeoxynucleotide (ssODN) is used as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b2164be5266708f8faa6fa66dc203d
Autor:
Martin A. Billeter, Frank Radecke
Publikováno v:
Reviews in Medical Virology. 7:49-63
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1133a5182d547867790c0b5137ad8a85
https://doi.org/10.1002/(sici)1099-1654(199704)7:1<49::aid-rmv181>3.0.co
https://doi.org/10.1002/(sici)1099-1654(199704)7:1<49::aid-rmv181>3.0.co
Autor:
Henriette Schneider, Gerd Sutter, Karin Kaelin, Martin A. Billeter, Frank Radecke, Pius Spielhofer, Christina Dötsch
Publikováno v:
Journal of Virological Methods. 64:57-64
A system which allows the reconstitution of measles virus (MV) from cloned cDNA is described. The severely host cell restricted vaccinia vector MVA-T7 expressing bacteriophage T7 RNA polymerase was used to generate full-length antigenomic MV RNA and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f721a5b447aa70f772a646df4d1fff6
https://doi.org/10.1016/s0166-0934(96)02137-4
https://doi.org/10.1016/s0166-0934(96)02137-4
Autor:
Frank Radecke, Martin A. Billeter, Mohinderjit S. Sidhu, Pius Spielhofer, Henriette Schneider, Malthi Masurekar, Stephen A. Udem, John Chan, Peter C. Dowling, Karin Kaelin
Publikováno v:
Virology. 208:800-807
Measles virus (MV) mRNA transcription and replication are thought to be controlled by cis -acting sequence elements contained within the terminal MV genomic noncoding nucleotides. To validate these promoter and regulatory signal assignments, cDNAs we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d16f0a673e396e6b83e1b2d852b6e3
https://doi.org/10.1006/viro.1995.1215
https://doi.org/10.1006/viro.1995.1215
Autor:
Fabienne Lütge, Sarah Radecke, Silke Glage, Eva Guhl, Nadine Dannemann, Toni Cathomen, Regine Heilbronn, Tobias Cantz, Anna Osiak, Frank Radecke, Cornelia Rudolph, Klaus Schwarz
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28911 (2011)
PLoS ONE
PLoS ONE; Vol 6
PLoS ONE
PLoS ONE; Vol 6
Gene knockout in murine embryonic stem cells (ESCs) has been an invaluable tool to study gene function in vitro or to generate animal models with altered phenotypes. Gene targeting using standard techniques, however, is rather inefficient and typical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4960dda5dca063e1493653d57cffe76
http://europepmc.org/articles/PMC3237556?pdf=render
http://europepmc.org/articles/PMC3237556?pdf=render
Publikováno v:
The journal of gene medicine. 8(2)
Background Targeted gene repair is an attractive method to correct point-mutated genes at their natural chromosomal sites, but it is still rather inefficient. As revealed by earlier studies, successful gene correction requires a productive interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1257d7e1a81681bf0f8ac2ea44f41651
https://pubmed.ncbi.nlm.nih.gov/16142817
https://pubmed.ncbi.nlm.nih.gov/16142817
Publikováno v:
The journal of gene medicine. 6(11)
Background A number of genetic defects in humans are due to point mutations in a single, often tightly regulated gene. Genetic treatment of such defects is preferably done by correcting only the altered base pair at the endogenous locus rather than b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea6135be43de1643ef07e161b31f3c9
https://pubmed.ncbi.nlm.nih.gov/15459968
https://pubmed.ncbi.nlm.nih.gov/15459968