Výsledky vyhledávání - "Frank R. Sinatra"

Impact of Sugar Reduction and PNPLA3 Genotype on Liver Fat, Liver Fibrosis, and Body Composition in Hispanic Youth With Obesity: A Randomized Controlled Trial

Autor: Roshonda B. Jones, Paige K. Berger, Jennifer L. Fogel, Krishna S. Nayak, Jasmine F. Plows, Michael I. Goran, Kelsey Schmidt, Allayee Hooman, Frank R. Sinatra, Tanya L. Alderete, Gregory A. Harlan

Publikováno v: Curr Dev Nutr

OBJECTIVES: Pediatric Non-Alcoholic Fatty Liver Disease is prevalent among Hispanics, which may partially result from a higher frequency of the C > G polymorphism in the patatin-like phospholipase 3 (PNPLA3) gene. Our prior work showed an interaction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4ca0c6d29a2064b4e81c72551f5c00
https://europepmc.org/articles/PMC8181853/

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PNPLA3 Genotype, Arachidonic Acid Intake, and Unsaturated Fat Intake Influences Liver Fibrosis in Hispanic Youth with Obesity

Autor: Suzanne L. Palmer, Krishna S. Nayak, Jasmine F. Plows, Frank R. Sinatra, Paige K. Berger, Tanya L. Alderete, Hooman Allayee, Claudia Rios, Michael I. Goran, Lide Arenaza, Roshonda B. Jones, Jennifer L. Fogel, Darryl Hwang, Rohit Kohli, Passant Mohamed

Publikováno v: Nutrients, Vol 13, Iss 1621, p 1621 (2021)
Nutrients
Volume 13
Issue 5

Non-alcoholic fatty liver disease impacts 15.2% of Hispanic adolescents and can progress to a build-up of scared tissue called liver fibrosis. If diagnosed early, liver fibrosis may be reversible, so it is necessary to understand risk factors. The ai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cce8ccc0f5d1a3f30ef56b9389e5600
https://doi.org/10.3390/nu13051621

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Macrophages and fibrosis in adipose tissue are linked to liver damage and metabolic risk in obese children

Autor: Michael I. Goran, Hooman Allayee, Anna Alisi, Valerio Nobili, Ryan W. Walker, Alessandro Inserra, Rodolfo Fruhwirth, Rita Devito, Frank R. Sinatra, Magalie E. Carey

Publikováno v: Obesity. 22:1512-1519

Objective: Obesity in childhood is associated with an inllammatory state in adipose tissue and liver, which elevates risk lor diabetes and liver disease. No prior study has examined associations between pathologies occurring in adipose tissue and liv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::133cea764dace8d101790dcce8188da9
https://doi.org/10.1002/oby.20730

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Genetic and clinical markers of elevated liver fat content in overweight and obese hispanic children

Autor: Tanya L. Alderete, Jaana Hartiala, Hooman Allayee, Donna Spruijt-Metz, Michael I. Goran, Frank R. Sinatra, Ryan W. Walker, Marc J. Weigensberg

Publikováno v: Obesity. 21:E790-E797

Objective Genetic variation in six genes has been associated with elevated liver fat and nonalcoholic fatty liver disease in adults. The influence of these genes on liver fat and whether a genetic risk score (GRS) would improve upon the ability of co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a5003df02b12410e8f1f07f852f292cf
https://doi.org/10.1002/oby.20523

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Durability of sustained response shown in paediatric patients with chronic hepatitis C who were treated with interferon alfa-2b plus ribavirin

Autor: Alain Lachaux, Helen S. Te, Stefan Wirth, Maureen M. Jonas, Janice K. Albrecht, W. Deng, Frank R. Sinatra, Barbara Haber, T. Lang, Jean P. Molleston, Henry Pollack, Michael R. Narkewicz, M Shelton, Karen F. Murray, Stephanie Noviello, DA Kelly, Regino P. Gonzalez-Peralta

Publikováno v: Journal of Viral Hepatitis. 19:263-270

Summary. Long-term studies in adults indicate that sustained virologic response (SVR) after combination treatment for chronic hepatitis C (CHC) predicts long-term clearance. Although peginterferon plus ribavirin is now standard care for children with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d63934bd9b76280b9f5b3594b145c96
https://doi.org/10.1111/j.1365-2893.2011.01544.x

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Autor: Sue V. McDiarmid, Jorge Vargas, Catherine S. Chao, Martin G. Martin, Harvey L. Sharp, Steven S. Wu, Marvin E. Ament, Frank R. Sinatra

Publikováno v: Transplantation. 84:173-179

Background. Isoniazid (INH) therapy for tuberculosis carries a known risk for hepatoxicity, and leads to hepatic failure in a small subset of patients. This incidence has been described for adults, but is uncertain in children. Our aim was to estimat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d1b4368db1395b1cbdc891bd0a1e64
https://doi.org/10.1097/01.tp.0000269104.22502.d2

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Liver Disease in Polyglandular Autoimmune Disease Type One: Clinicopathologic Study of Three Patients and Review of the Literature

Autor: Frank R. Sinatra, Philip J. Rosenthal, Louis P. Dehner, Neal S. Goldstein

Publikováno v: Pediatric Pathology & Laboratory Medicine. 16:625-636

We report the findings from liver biopsies of three patients with polyglandular autoimmune disease type 1. The livers in two patients had histologic features of chronic hepatitis that eventuated in bridging fibrosis and arrhosis over a period of seve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b4acf74adfab2e1dd8b1400d5e48f12
https://doi.org/10.1080/15513819609168698

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Nonalcoholic fatty liver disease in pediatric patients

Autor: Frank R. Sinatra

Publikováno v: JPEN. Journal of parenteral and enteral nutrition. 36

Nonalcoholic fatty liver disease is a spectrum of liver disease ranging from simple hepatic steatosis to steatohepatitis, hepatic fibrosis, and cirrhosis. It is highly associated with obesity and insulin resistance, and with the dramatic increase in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809bf9da6bb23fb0286a1fb69d21d605
https://pubmed.ncbi.nlm.nih.gov/22237882

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