Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Frank Mastrogiacomo"'
Autor:
Polina Mironova, Sebastian Tomescu, Oleg Safir, Tosan Okoro, Martin Gargan, Yaron Zaulan, Paul Wong, Veronica Wadey, William Kraemer, Markku Nousianien, Stewart Wright, Hilary Felice, Jonathan Peck, Tim Dwyer, Frank Mastrogiacomo, Christine Walton, Steven Borland, John Murnaghan, Ian Whatley, Hans J. Kreder, Tyler MacGregor, Jennah Mann, Jack I. Williams, Terry Axelrod, Meghan Crookshank, Jermey Hall, Thrmiga Sathiyamoorthy, Peter C. Ferguson, Peter J. Weiler, Christian Elgoff, Eitan Ganz
Background: The research team aimed to assess the relationship between performance in a competency-based curriculum (CBC) evaluation, and the Orthopaedic In-Training Examination (OITE) in the Postgraduate Year 1 (PGY1) cohort of 2016-2017.Methods: Af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15d661df36e9442f06b4840973c865f8
https://doi.org/10.21203/rs.3.rs-426917/v1
https://doi.org/10.21203/rs.3.rs-426917/v1
Autor:
Lucien Bettendorff, Thierry Grisar, Pierre Wins, Stephen J. Kish, Melvyn J. Ball, Frank Mastrogiacomo
Publikováno v:
Journal of Neurochemistry. 69:2005-2010
We compared the thiamine and thiamine phosphate contents in the frontal, temporal, parietal, and occipital cortex of six patients with frontal lobe degeneration of the non-Alzheimer's type (FNAD) or frontotemporal dementia with five age-, postmortem
Autor:
Slobodan Dozic, Linda DiStefano, Jacques Lamarche, Yoshiaki Furukawa, Jan-Willem Taanman, Massimo Pandolfo, Mark Guttman, Frank Mastrogiacomo, Li-Jan Chang, Stephen J. Kish
Publikováno v:
Journal of Neurochemistry. 72:700-707
Controversy exists as to the clinical importance, cause, and disease specificity of the cytochrome oxidase (CO) activity reduction observed in some patients with Alzheimer's disease (AD). Although it is assumed that the enzyme is present in normal am
Publikováno v:
Annals of Neurology. 39:592-598
To determine whether the reduction in brain alpha-ketoglutarate dehydrogenase complex activity in Alzheimer's disease (AD) is associated with an abnormality in one of its three constituent enzyme subunits, we measured protein levels of alpha-ketoglut
Publikováno v:
Annals of Neurology. 39:585-591
Clinical data suggest that high-dose thiamine (vitamin B1) may have a mild beneficial effect in some patients with Alzheimer's disease (AD). Since this action could be related to a brain thiamine deficiency, we measured directly levels of free (nonph
Publikováno v:
Journal of Neurochemistry. 61:2007-2014
We measured the activity of the a-ketoglutarate dehydrogenase complex (α-KGDHC), a rate-limiting Krebs cycle enzyme, in postmortem brain samples from 38 controls and 30 neuropathologically confirmed Alzheimer's disease (AD) cases, in both the presen
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 11(4)
Decreased blood and cerebrospinal fluid levels of thiamine have been reported in patients with spinocerebellar ataxia disorders. To determine whether a thiamine deficiency is present in the brain, we measured levels of thiamine and its phosphate este
Autor:
Yves Robitaille, Jacques Lamarche, Frank Mastrogiacomo, Gordon J. Lindsay, Stephen J. Kish, Lucien Bettendorff, Slobodan Dozic, Lawrence J. Schut
Publikováno v:
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. 5(1)
Enzyme activities of a alpha-ketoglutarate dehydrogenase complex (alpha KGDHC) and one of its constituent subunits, dihydrolipoamide dehydrogenase (E3), are reported to be reduced in non-CNS tissues of some patients with Friedreich's ataxia (FA); how
Publikováno v:
Journal of neurochemistry. 66(1)
Total thiamine (the sum of thiamine and its phosphate esters) concentrations are two- to fourfold lower in human brain than in the brain of other mammals. There were no differences in the total thiamine content between biopsied and autopsied human br
Autor:
Stephen J. Kish, Frank Mastrogiacomo
Publikováno v:
Annals of neurology. 35(5)
We measured the activity of the thiamine pyrophosphate-dependent enzyme alpha-ketoglutarate dehydrogenase complex in postmortem brain of 12 patients with the spinocerebellar ataxia type 1 form of olivopontocerebellar atrophy. alpha-Ketoglutarate dehy