Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Frank Markland"'
Autor:
Amy S. Lee, Susan E. Bates, John B. Patterson, Caryn Stiles, Frank Markland, Fritz Costa, Steven Swenson, Peter Baumeister, Bryce Ko, Dezheng Dong
Therapeutic targeting of the tumor vasculature that destroys preexisting blood vessels of the tumor and antiangiogenesis therapy capitalize on the requirement of tumor cells on an intact vascular supply for oxygen and nutrients for growth, expansion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb276a5ed007a8a768f2ba0d98125ac
https://doi.org/10.1158/0008-5472.c.6493880
https://doi.org/10.1158/0008-5472.c.6493880
Autor:
Amy S. Lee, Susan E. Bates, John B. Patterson, Caryn Stiles, Frank Markland, Fritz Costa, Steven Swenson, Peter Baumeister, Bryce Ko, Dezheng Dong
Supplementary Data from Vascular Targeting and Antiangiogenesis Agents Induce Drug Resistance Effector GRP78 within the Tumor Microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27cf682b88ff0f887819ba7ed130295
https://doi.org/10.1158/0008-5472.22363754.v1
https://doi.org/10.1158/0008-5472.22363754.v1
Autor:
Steve Swenson, Martha K. Pastuszka, Frank Markland, Peter S. Conti, Zibo Li, Siti M. Janib, Radu O. Minea, Shuanglong Liu, J. Andrew MacKay
Publikováno v:
Advanced Materials Research. 1024:287-291
The goal of our study is to develop genetically engineered polypeptides that self-assemble into nanoparticulates, which can present functional moieties on their exterior and sequester drugs and/or imaging agents within their interior. These particula
Publikováno v:
Proceedings of the 2016 International Conference on Biomedical and Biological Engineering.
The 5-year survival is only about 30% when ovarian cancer (OC) is first detected at an advanced stage, which is the case for ~70% of women with OC. The combination of debulking surgery and cytotoxic chemotherapy is the primary treatment modality for
Publikováno v:
Acta Biomaterialia. 7:3746-3756
To introduce the adhesion site of proteins and/or cells on parylene C (PC)-coated medical devices that can be used as implantable biosensors or drug delivery capsules, the PC surfaces were initially modified by the Friedel–Crafts acylation reaction
Autor:
Bryce Ko, Fritz Costa, Dezheng Dong, John B. Patterson, Frank Markland, Peter Baumeister, Steven Swenson, Susan E. Bates, Caryn Stiles, Amy S. Lee
Publikováno v:
Cancer Research. 65:5785-5791
Therapeutic targeting of the tumor vasculature that destroys preexisting blood vessels of the tumor and antiangiogenesis therapy capitalize on the requirement of tumor cells on an intact vascular supply for oxygen and nutrients for growth, expansion
Autor:
Henry F. Frierson, Mark R. Conaway, Frank Markland, Matthew Coyner, John M. Sanders, Martin A. Schwartz, Dan Theodorescu, Kevin S. McRoberts, Kumari L. Andarawewa, Stephen Swenson
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 14(19)
Purpose: Metastatic melanomas are generally resistant to chemotherapy and radiation, even when wild-type for p53. These tumors often grow in small nests where many of the cells have little contact with extracellular matrix (ECM). Previous work showed
Autor:
Helen Chen, Gini F. Fleming, H Hirte, Sidney A. Scudder, David R. Gandara, Amit M. Oza, Agustin A. Garcia, Frank Markland, L. Roman, Dongyun Yang, Heinz-Josef Lenz, Robert J. Morgan, Denice D. Tsao-Wei, Steve Swenson, Susan Groshen
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 26(1)
Purpose Vascular endothelial growth factor (VEGF) plays an important role in the biology of ovarian cancer (OC). Inhibitors of VEGF suppress tumor growth in OC models. Metronomic chemotherapy, defined as frequent administration of low doses of cytoto