Výsledky vyhledávání - "Frank M. Sirotnak"

Pulsatile Administration of the Epidermal Growth Factor Receptor Inhibitor Gefitinib Is Significantly More Effective than Continuous Dosing for Sensitizing Tumors to Paclitaxel

Autor: Frank M. Sirotnak, Neal Rosen, Jose Lobo, Howard I. Scher, Mark G. Kris, Yuhong She, David B. Solit

Publikováno v: Clinical Cancer Research. 11:1983-1989

Purpose: Gefitinib is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. Continuous inhibition of EGFR signaling is thought necessary for optimal inhibition of tumor cell proliferation. We hypothesized that continuous gefiti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a7e0f042dd206d3d7fdb26b921bd2d
https://doi.org/10.1158/1078-0432.ccr-04-1347

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