Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Frank M. J. Jacobs"'
Autor:
Nilda Vanesa Ayala-Nunez, Gautier Follain, François Delalande, Aurélie Hirschler, Emma Partiot, Gillian L. Hale, Brigid C. Bollweg, Judith Roels, Maxime Chazal, Florian Bakoa, Margot Carocci, Sandrine Bourdoulous, Orestis Faklaris, Sherif R. Zaki, Anita Eckly, Béatrice Uring-Lambert, Frédéric Doussau, Sarah Cianferani, Christine Carapito, Frank M. J. Jacobs, Nolwenn Jouvenet, Jacky G. Goetz, Raphael Gaudin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Zika virus (ZIKV) can infect the central nervous system, but it is not clear how it reaches the brain. Here, Ayala-Nunez et al. show in ex vivo and in vivo models that ZIKV can hitch a ride in monocytes in a Trojan Horse manner to cross the endotheli
Externí odkaz:
https://doaj.org/article/80c8125c989f4ad684da8d5bd8592317
Autor:
Marc Galland, Fred T.G. White, Gonzalo Congrains Sotomayor, Tiziana M. Hey, Nina L. Haring, Judith R.E. Roels, Marten P. Smidt, Whitney S. Jordaan, Elisabeth J. van Bree, Frank M. J. Jacobs
Publikováno v:
Genome Res
Genome Research, 31(4), 551-563. Cold Spring Harbor Laboratory Press
Genome Research, 31(4), 551-563. Cold Spring Harbor Laboratory Press
Transposable element (TE) invasions have shaped vertebrate genomes over the course of evolution. They have contributed an extra layer of species-specific gene regulation by providing novel transcription factor binding sites. In humans, SINE-VNTR-Alu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca170b4e4a7d94b653a5bad5c29d240
https://doi.org/10.1101/gr.265348.120
https://doi.org/10.1101/gr.265348.120
Autor:
Andrew R. Field, Max Hauessler, Frank M. J. Jacobs, Mari Olsen, Sofie R. Salama, David Haussler, Sol Katzman, Ian T. Fiddes, Alex P.R. Phillips, Vincent Meng, Erin LaMontagne, Andrea M. Reyes-Ortiz, Lila Whitehead, Jimi L. Rosenkrantz
Publikováno v:
Stem Cell Reports, Vol 12, Iss 2, Pp 245-257 (2019)
Stem cell reports, vol 12, iss 2
Stem Cell Reports
Stem cell reports, vol 12, iss 2
Stem Cell Reports
Summary The cerebral cortex has expanded in size and complexity in primates, yet the molecular innovations that enabled primate-specific brain attributes remain obscure. We generated cerebral cortex organoids from human, chimpanzee, orangutan, and rh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d75b87c1d91ffd2b91bde30906bbed
https://doi.org/10.1016/j.stemcr.2018.12.006
https://doi.org/10.1016/j.stemcr.2018.12.006
Autor:
Frank M. J. Jacobs, Iraklis Vretzakis, Diana Pereira Fernandes, Gerrald A Lodewijk, Jeanne E. Savage
Publikováno v:
Lodewijk, G A, Fernandes, D P, Vretzakis, I, Savage, J E & Jacobs, F M J 2020, ' Evolution of Human Brain Size-Associated NOTCH2NL Genes Proceeds toward Reduced Protein Levels ', Molecular biology and evolution, vol. 37, no. 9, pp. 2531-2548 . https://doi.org/10.1093/molbev/msaa104
Molecular Biology and evolution, 37(9). Oxford University Press
Molecular biology and evolution, 37(9), 2531-2548. Oxford University Press
Molecular Biology and Evolution
Molecular Biology and evolution, 37(9). Oxford University Press
Molecular biology and evolution, 37(9), 2531-2548. Oxford University Press
Molecular Biology and Evolution
Ever since the availability of genomes from Neanderthals, Denisovans, and ancient humans, the field of evolutionary genomics has been searching for protein-coding variants that may hold clues to how our species evolved over the last ∼600,000 years.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d72d5a47c1ee7cc47127cfcd9085d7
https://research.vu.nl/en/publications/227af790-ab0e-4315-a6ba-0e89a0695bac
https://research.vu.nl/en/publications/227af790-ab0e-4315-a6ba-0e89a0695bac
Autor:
Gerrald A Lodewijk, Elisabeth J. van Bree, Frank M. J. Jacobs, Grace Farmiloe, Stijn F Robben
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences
Philosophical Transactions of the Royal Society B-Biological Sciences, 375(1795):20190333. Royal Society of London
Philos Trans R Soc Lond B Biol Sci
Philosophical Transactions of the Royal Society B-Biological Sciences, 375(1795):20190333. Royal Society of London
Philos Trans R Soc Lond B Biol Sci
The large family of KRAB zinc finger (KZNF) genes are transcription factors implicated in recognizing and repressing repetitive sequences such as transposable elements (TEs) in our genome. Through successive waves of retrotransposition-mediated inser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82f86ee08789eee613eb1bb345d373b
https://doi.org/10.1098/rstb.2019.0333
https://doi.org/10.1098/rstb.2019.0333
Autor:
Maximilian Haeussler, Meghan Mooring, David Haussler, Gary L. Mantalas, Marie-Claude Addor, Max L. Dougherty, Colleen M. Bosworth, Xander Nuttle, Andrew R. Field, Alex Bishara, Alex A. Pollen, Lotte Russo, Arnold R. Kriegstein, Simon Zwolinski, Gerrald A Lodewijk, Adam D. Ewing, Aparna Bhaduri, Jimi L. Rosenkrantz, Ryan Lorig-Roach, Sofie R. Salama, Frank M. J. Jacobs, Anouk van den Bout, Adam M. Novak, Tomasz J. Nowakowski, Evan E. Eichler, Ian T. Fiddes, Sol Katzman
Publikováno v:
Cell, vol 173, iss 6
Cell, 173(6), 1356-1369. Cell Press
Cell
Cell, 173(6), 1356-1369. Cell Press
Cell
Genetic changes causing brain size expansion in human evolution have remained elusive. Notch signaling is essential for radial glia stem cell proliferation and is a determinant of neuronal number in the mammalian cortex. We find that three paralogs o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4212839d713447491e7e090e98d2e962
https://dare.uva.nl/personal/pure/en/publications/humanspecific-notch2nl-genes-affect-notch-signaling-and-cortical-neurogenesis(747a3209-ee89-4d1b-b3c2-fa7b89b4852d).html
https://dare.uva.nl/personal/pure/en/publications/humanspecific-notch2nl-genes-affect-notch-signaling-and-cortical-neurogenesis(747a3209-ee89-4d1b-b3c2-fa7b89b4852d).html
Autor:
Emma Partiot, Nilda Vanesa Ayala-Nunez, Jacky G. Goetz, Gautier Follain, Judith R.E. Roels, Anita Eckly, Béatrice Uring-Lambert, Maxime Chazal, Raphael Gaudin, Gillian Hale, Frank M. J. Jacobs, Sandrine Bourdoulous, Orestis Faklaris, Sherif R. Zaki, Aurélie Hirschler, Nolwenn Jouvenet, Margot Carocci, Florian Bakoa, Sarah Cianférani, Christine Carapito, Frédéric Doussau, Brigid C. Bollweg, François Delalande
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.4430. ⟨10.1038/s41467-019-12408⟩
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications, 2019, 10 (1), pp.4430. ⟨10.1038/s41467-019-12408⟩
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-12408-x⟩
Nature Communications, 10(1):4430. Nature Publishing Group
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.4430. ⟨10.1038/s41467-019-12408⟩
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications, 2019, 10 (1), pp.4430. ⟨10.1038/s41467-019-12408⟩
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-12408-x⟩
Nature Communications, 10(1):4430. Nature Publishing Group
Zika virus (ZIKV) invades and persists in the central nervous system (CNS), causing severe neurological diseases. However the virus journey, from the bloodstream to tissues through a mature endothelium, remains unclear. Here, we show that ZIKV-infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde45bf7344e2f30ce082f9779330683
https://hal.archives-ouvertes.fr/hal-02327473/file/s41467-019-12408-x.pdf
https://hal.archives-ouvertes.fr/hal-02327473/file/s41467-019-12408-x.pdf
Publikováno v:
Non-Coding RNA
The expansion of long non-coding RNAs (lncRNAs) in organismal genomes has been associated with the emergence of sophisticated regulatory networks that may have contributed to more complex neuronal processes, such as higher-order cognition. In line wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0c468b6a1421df2ff757c2614e899f
https://doi.org/10.3390/ncrna4020012
https://doi.org/10.3390/ncrna4020012
Autor:
Sofie R. Salama, Maximilian Haeussler, Andrea M. Reyes-Ortiz, Sol Katzman, Ian T. Fiddes, Alex P.R. Phillips, Lila Whitehead, Erin LaMontagne, Vincent Meng, David Haussler, Andrew R. Field, Jimi L. Rosenkrantz, Frank M. J. Jacobs
Publikováno v:
SSRN Electronic Journal.
The cerebral cortex has expanded in size and complexity in primates, yet the underlying molecular mechanisms are obscure. We generated cortical organoids from human, chimpanzee, orangutan, and rhesus pluripotent stem cells and sequenced their transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea2002eb65e90f5bc61ed23d766e4859
https://doi.org/10.2139/ssrn.3155810
https://doi.org/10.2139/ssrn.3155810
Autor:
Song Pang, Frank M. J. Jacobs, Michael E. Coulter, Raphael Gaudin, C. Shan Xu, Gerrald A Lodewijk, Ganeshwaran H. Mochida, Sarah Cianférani, Harald F. Hess, Wei-Chung Allen Lee, Christopher A. Walsh, Tomas Kirchhausen, Dilenny M. Gonzalez, Monica L. Calicchio, François Delalande, Edward Yang, Cristina M. Dorobantu, Richard S. Smith, Hart G.W. Lidov, David Haussler, Eric T. Wong, Vijay S. Ganesh, Maria K. Lehtinen, Elaine T. Lim, Thorsten M. Schlaeger
Publikováno v:
Cell reports, vol 24, iss 4
Cell reports
Cell Reports, 24(4), 973-986. Cell Press
Cell Reports
Cell Reports, Elsevier Inc, 2018, 24 (4), pp.973-986.e8. ⟨10.1016/j.celrep.2018.06.100⟩
Cell reports
Cell Reports, 24(4), 973-986. Cell Press
Cell Reports
Cell Reports, Elsevier Inc, 2018, 24 (4), pp.973-986.e8. ⟨10.1016/j.celrep.2018.06.100⟩
SUMMARY Endosomal sorting complex required for transport (ESCRT) complex proteins regulate biogenesis and release of extracellular vesicles (EVs), which enable cell-to-cell communication in the nervous system essential for development and adult funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d13408544f44c62adec62a2110dd84