Zobrazeno 1 - 10
of 372
pro vyhledávání: '"Frank M Faraci"'
Autor:
Sanjana Dayal, Gary L Baumbach, Erland Arning, Teodoro Bottiglieri, Frank M Faraci, Steven R Lentz
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175732 (2017)
There is an emerging consensus that hyperhomocysteinemia is an independent risk factor for cerebral vascular disease and that homocysteine-lowering therapy protects from ischemic stroke. However, the mechanisms by which hyperhomocysteinemia produces
Externí odkaz:
https://doaj.org/article/122c17f46df3401897561a87f4f40758
Autor:
Sanjana Dayal, Ilya O Blokhin, Rochelle A Erger, Melissa Jensen, Erland Arning, Jeff W Stevens, Teodoro Bottiglieri, Frank M Faraci, Steven R Lentz
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107734 (2014)
Diet-induced hyperhomocysteinemia produces endothelial and cardiac dysfunction and promotes thrombosis through a mechanism proposed to involve oxidative stress. Inducible nitric oxide synthase (iNOS) is upregulated in hyperhomocysteinemia and can gen
Externí odkaz:
https://doaj.org/article/1a5112c05e564e9a92018844526c218e
Publikováno v:
Physiological Reports, Vol 10, Iss 11, Pp n/a-n/a (2022)
Abstract The renin‐angiotensin system (RAS) contributes to vascular disease with multiple cardiovascular risk factors including hypertension. As a major effector within the RAS, angiotensin II (Ang II) activates diverse signaling mechanisms that af
Externí odkaz:
https://doaj.org/article/7eb0d10f5c594a0fb278d4603f41eb6d
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 323(6)
Changes in vascular structure contribute to vascular events and loss of brain health. We examined the inherent structural plasticity of cerebral arterioles during and after a period of hypertension. Arteriolar wall thickness, diameter, wall-to-lumen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03affc2b2c1184a83d6b7130794fedf3
https://pubmed.ncbi.nlm.nih.gov/36269650
https://pubmed.ncbi.nlm.nih.gov/36269650
Autor:
Frank M. Faraci
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:852-854
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15aa558d4bedb37b8063a227a34cd7f8
https://doi.org/10.1161/atvbaha.123.319285
https://doi.org/10.1161/atvbaha.123.319285
Autor:
T. Michael De Silva, Frank M. Faraci
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629253
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64f42e8acd2782e0148bf383415ddaa4
https://doi.org/10.1007/978-1-0716-2926-0_34
https://doi.org/10.1007/978-1-0716-2926-0_34
Autor:
Frank M. Faraci
Publikováno v:
J Clin Invest
Dementia resulting from small vessel diseases (SVDs) of the brain is an emerging epidemic for which there is no treatment. Hypertension is the major risk factor for SVDs, but how hypertension damages the brain microcirculation is unclear. Here, we sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4af3f70fe10aea95f39c69d787a4333
https://doi.org/10.1172/jci153202
https://doi.org/10.1172/jci153202
Publikováno v:
Stroke
Background and Purpose: Hypertension is a leading risk factor for cerebrovascular disease and loss of brain health. While the brain renin-angiotensin system (RAS) contributes to hypertension, its potential impact on the local vasculature is unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61922dca78f9b36772b7fc8896bf743f
https://europepmc.org/articles/PMC8262118/
https://europepmc.org/articles/PMC8262118/
Autor:
John A. Wemmie, Frank M. Faraci, Subhash C. Gupta, Cynthia M. Lynch, Rong Fan, Rebecca J. Taugher
Publikováno v:
Circ Res
Rationale: Precise regulation of cerebral blood flow is critical for normal brain function. Insufficient cerebral blood flow contributes to brain dysfunction and neurodegeneration. Carbon dioxide (CO 2 ), via effects on local acidosis, is one of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ead7f5083b6c895cdad109c8f3ba65
https://doi.org/10.1161/circresaha.119.315024
https://doi.org/10.1161/circresaha.119.315024
Publikováno v:
Physiol Rev
Physiological Reviews, 101, 1487-1559
Physiological Reviews, 101, 4, pp. 1487-1559
Physiological Reviews, 101, 1487-1559
Physiological Reviews, 101, 4, pp. 1487-1559
Contains fulltext : 238817.pdf (Publisher’s version ) (Closed access) Brain function critically depends on a close matching between metabolic demands, appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5b382f6308765a2f31b985a72d19f6
https://europepmc.org/articles/PMC8576366/
https://europepmc.org/articles/PMC8576366/