Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Frank M, Yatsu"'
Publikováno v:
Pharmaceuticals, Vol 5, Iss 9, Pp 925-943 (2012)
The histone deacetylase (HDAC) inhibitors, butyrate and trichostatin A (TSA), are epigenetic histone modifiers and proliferation inhibitors by downregulating cyclin D1, a positive cell cycle regulator, and upregulating p21Cip1 and INK family of prote
Externí odkaz:
https://doaj.org/article/01b97748a1bc430ba788160c2aa90d25
Publikováno v:
Pharmaceuticals, Vol 5, Iss 9, Pp 925-943 (2012)
Pharmaceuticals
Volume 5
Issue 9
Pages 925-943
Pharmaceuticals
Volume 5
Issue 9
Pages 925-943
The histone deacetylase (HDAC) inhibitors, butyrate and trichostatin A (TSA), are epigenetic histone modifiers and proliferation inhibitors by downregulating cyclin D1, a positive cell cycle regulator, and upregulating p21Cip1 and INK family of prote
Publikováno v:
Biomedicine & Pharmacotherapy. 64:733-740
HDACs and HATs regulate histone acetylation, an epigenetic modification that controls chromatin structure and through it, gene expression. Butyrate, a dietary HDAC inhibitor, inhibits VSMC proliferation, a crucial factor in atherogenesis, and the pri
Publikováno v:
Vascular Disease Prevention. 3:375-390
Autor:
Frank M. Yatsu, Omana P. Mathew, Shirlette G. Milton, Barbara E. Hayes, Kasturi Ranganna, Zivar Yousefipour
Publikováno v:
FEBS Journal. 274:5962-5978
Vascular smooth muscle cell (VSMC) proliferation is an important etiological factor in vascular proliferative diseases such as primary atherosclerosis, hypertension, arterial and in-stent restenosis, and transplant vasculopathy. Our studies establish
Autor:
Jo Leonardi-Bee, Michael E. Dewey, Frank M. Yatsu, Hans-Christoph Diener, Marie-Germaine Bousser, Antoni Dávalos, Philip M.W. Bath, Bernard Guiraud-Chaumeil, Juhani Sivenius
Publikováno v:
Stroke. 36:162-168
Background and Purpose—Results from randomized controlled trials of dipyridamole, given with or without aspirin, for secondary prevention after ischemic stroke or transient ischemic attack (TIA) have given conflicting results. We performed a meta-a
Publikováno v:
Molecular and Cellular Biochemistry. 254:21-36
Excessive proliferation of vascular smooth muscle cells (VSMCs) is a critical element in the development of several vascular pathologies, particularly in atherosclerosis and in restenosis due to angioplasty. We have shown that butyrate, a powerful an
Autor:
Rami Nasif, Shirlette G. Milton, Kasturi Ranganna, Barbara E. Hayes, Frank M. Yatsu, Zivar Yousefipour
Publikováno v:
Molecular and Cellular Biochemistry. 240:83-98
Acrolein, a major component of cigarette smoke, an environmental pollutant and an endogenous lipid peroxidation product, has been implicated in the development of atherosclerosis. Although a link between vascular injury and acrolein has been indicate
Publikováno v:
Molecular and Cellular Biochemistry. 205:149-161
Arterial injury-induced vascular smooth muscle cell (VSMC) proliferation in intima is the important etiologic factor in vascular proliferative disorders such as atherosclerosis, hypertension and restenosis after balloon angioplasty. Butyrate, a natur
Autor:
Derk Krieger, Carlos Villar-Cordova, James C. Grotta, Frank M. Yatsu, Patti Bratina, Scott E. Kasner, David Chiu, Lewis B. Morgenstern
Publikováno v:
Stroke. 29:18-22
Background and Purpose —The feasibility, safety, and efficacy of intravenous tissue plasminogen activator (t-PA) for patients with acute ischemic stroke in clinical practice need to be assessed. Methods —We initiated a prospective open-label stud