Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Frank Loehr"'
Autor:
N. Berner, Magda Szewczyk, B. Kuester, J. Weckesser, Martin Eilers, Andreas Kraemer, Christoph A. Sotriffer, Volker Doetsch, Bikash Adhikari, Frank Loehr, Stephanie Heinzlmeir, Dalia Barsyte-Lovejoy, A. Doelle, Mathias Diebold, Elmar Wolf, J. Gerbel, Lena M. Berger, Stefan Knapp, Cheryl H. Arrowsmith
Histone H3K4 methylation serves as post-translational hallmark of actively transcribed genes and is introduced by histone methyltransferases (HMT) and its regulatory scaffolding proteins. One of these is the WD-repeat containing protein 5 (WDR5) that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bb60d0d7a9cb8061918d0989716e03b
https://doi.org/10.1101/2021.04.12.439490
https://doi.org/10.1101/2021.04.12.439490
Lysosomal targeting of the ABC transporter TAPL is determined by membrane-localized charged residues
Autor:
Rupert Abele, Christian Behrends, Philipp Graab, Konstantin Weiss, Alexander Hirth, Frank Loehr, Jennifer Jung, Nicole Koller, Markus Braner, Christoph Bock, Robert Tampé
Publikováno v:
J Biol Chem
The human lysosomal polypeptide ABC transporter TAPL (ABC subfamily B member 9, ABCB9) transports 6-59-amino-acid-long polypeptides from the cytosol into lysosomes. The subcellular localization of TAPL depends solely on its N-terminal transmembrane d
Autor:
Jessica Huber, Masato Akutsu, Masaaki Komatsu, Sabrina Habisov, Volker Doetsch, Terje Johansen, Vladimir Kirkin, David G. McEwan, Vladimir V. Rogov, Yoshinobu Ichimura, Ivan Dikic, Frank Loehr, Natalia Yu. Rogova
The covalent conjugation of ubiquitin-fold modifier 1 (UFM1) to proteins generates a signal that regulates transcription, response to cell stress, and differentiation. Ufmylation is initiated by ubiquitin-like modifier activating enzyme 5 (UBA5), whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a7337ad6d4fce9398b930e6644f469
https://hdl.handle.net/10037/24732
https://hdl.handle.net/10037/24732
Autor:
Hana Cerna, Josef Pasulka, Richard Štefl, Ctirad Hofr, Karel Kubíček, Frank Loehr, Stepanka Vanacova, Dominika Hrossova, Peter Holub
Publikováno v:
Genes & Development. 26:1891-1896
Recruitment of appropriate RNA processing factors to the site of transcription is controlled by post-translational modifications of the C-terminal domain (CTD) of RNA polymerase II (RNAP II). Here, we report the solution structure of the Ser5 phospho
Autor:
Eduardo Barbosa-Sicard, Frank Loehr, Manfred Schubert-Zsilavecz, Dieter Steinhilber, Janosch Achenbach, Franca-Maria Klingler, Mirjam Schroeder, Ewgenij Proschak, Volker Doetsch, Steffen Hahn, Estella Buscató, Ingrid Fleming, Jan Heering, Karin Meirer, Martina Hieke
Publikováno v:
ChemMedChem. 6:2146-2149
Autor:
Mirjam Schroeder, Janosch Achenbach, Steffen Hahn, Frank Loehr, Dieter Steinhilber, Franca-Maria Klingler, Ewgenij Proschak, Svenja Dorothea Steinbrink, Volker Doetsch
Publikováno v:
Journal of Cheminformatics, Vol 4, Iss Suppl 1, p P57 (2012)
Journal of Cheminformatics
Journal of Cheminformatics
In the recent years the prevalent paradigm in drug discovery of „one drug – one target – one disease“, following the assumption that highly selective ligands would avoid unwandted side effects caused by binding to seconday non-theratpeutic ta