Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Frank Lieberman"'
Autor:
Frank Lieberman
Publikováno v:
F1000Research, Vol 6 (2017)
This is an exciting time in neuro-oncology. Discoveries elucidating the molecular mechanisms of oncogenesis and the molecular subtypes of glioblastoma multiforme (GBM) have led to new diagnostic and classification schemes with more prognostic power t
Externí odkaz:
https://doaj.org/article/d4d815c770cf41749b0b2151353246fb
Autor:
Ingo K. Mellinghoff, Timothy F. Cloughesy, Minesh P. Mehta, Paul S. Mischel, John G. Kuhn, William H. Yong, Lisa M. DeAngelis, Andrew B. Lassman, Nian Wu, Steve Horvath, Howard A. Fine, Michael D. Prados, Susan M. Chang, Kathleen R. Lamborn, Patrick Y. Wen, Jan Drappatz, David A. Reardon, Mark R. Gilbert, W. K. Alfred Yung, Frank Lieberman, Linda M. Liau, Adriana Heguy, Cameron W. Brennan, Alicia Pedraza, Julie Dang, Daisuke Kuga, Akio Iwanami, Shaojun Zhu, Hui Tao, Nicolas Yannuzzi, Milan G. Chheda, Barbara Oldrini, Sara Kubek, Phioanh Leia Nghiemphu, Christian Grommes, Carl Campos, Daniel Rohle, H. Ian Robins, Igor Vivanco
mp3 file (11 MB). In the May edition of the Cancer Discovery podcast, Science Writer Elizabeth McKenna talks with Ingo K. Mellinghoff about his paper, which suggests that the disappointing clinical activity of first-generation EGFR inhibitors in glio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ea84dde1575a2f19855b3499939fbe
https://doi.org/10.1158/2159-8290.22529031.v1
https://doi.org/10.1158/2159-8290.22529031.v1
Autor:
Ingo K. Mellinghoff, Timothy F. Cloughesy, Minesh P. Mehta, Paul S. Mischel, John G. Kuhn, William H. Yong, Lisa M. DeAngelis, Andrew B. Lassman, Nian Wu, Steve Horvath, Howard A. Fine, Michael D. Prados, Susan M. Chang, Kathleen R. Lamborn, Patrick Y. Wen, Jan Drappatz, David A. Reardon, Mark R. Gilbert, W. K. Alfred Yung, Frank Lieberman, Linda M. Liau, Adriana Heguy, Cameron W. Brennan, Alicia Pedraza, Julie Dang, Daisuke Kuga, Akio Iwanami, Shaojun Zhu, Hui Tao, Nicolas Yannuzzi, Milan G. Chheda, Barbara Oldrini, Sara Kubek, Phioanh Leia Nghiemphu, Christian Grommes, Carl Campos, Daniel Rohle, H. Ian Robins, Igor Vivanco
PDF file - 689K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025f5ec99aaea9c2cde7f69d10999a40
https://doi.org/10.1158/2159-8290.22529022
https://doi.org/10.1158/2159-8290.22529022
Autor:
Ingo K. Mellinghoff, Timothy F. Cloughesy, Minesh P. Mehta, Paul S. Mischel, John G. Kuhn, William H. Yong, Lisa M. DeAngelis, Andrew B. Lassman, Nian Wu, Steve Horvath, Howard A. Fine, Michael D. Prados, Susan M. Chang, Kathleen R. Lamborn, Patrick Y. Wen, Jan Drappatz, David A. Reardon, Mark R. Gilbert, W. K. Alfred Yung, Frank Lieberman, Linda M. Liau, Adriana Heguy, Cameron W. Brennan, Alicia Pedraza, Julie Dang, Daisuke Kuga, Akio Iwanami, Shaojun Zhu, Hui Tao, Nicolas Yannuzzi, Milan G. Chheda, Barbara Oldrini, Sara Kubek, Phioanh Leia Nghiemphu, Christian Grommes, Carl Campos, Daniel Rohle, H. Ian Robins, Igor Vivanco
PDF file - 104K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb661e94c988b70550298ec4f5bac77
https://doi.org/10.1158/2159-8290.22529019
https://doi.org/10.1158/2159-8290.22529019
Autor:
Ingo K. Mellinghoff, Timothy F. Cloughesy, Minesh P. Mehta, Paul S. Mischel, John G. Kuhn, William H. Yong, Lisa M. DeAngelis, Andrew B. Lassman, Nian Wu, Steve Horvath, Howard A. Fine, Michael D. Prados, Susan M. Chang, Kathleen R. Lamborn, Patrick Y. Wen, Jan Drappatz, David A. Reardon, Mark R. Gilbert, W. K. Alfred Yung, Frank Lieberman, Linda M. Liau, Adriana Heguy, Cameron W. Brennan, Alicia Pedraza, Julie Dang, Daisuke Kuga, Akio Iwanami, Shaojun Zhu, Hui Tao, Nicolas Yannuzzi, Milan G. Chheda, Barbara Oldrini, Sara Kubek, Phioanh Leia Nghiemphu, Christian Grommes, Carl Campos, Daniel Rohle, H. Ian Robins, Igor Vivanco
PDF file - 133K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb57c1393865c3b35670662aac40d7a
https://doi.org/10.1158/2159-8290.22529025.v1
https://doi.org/10.1158/2159-8290.22529025.v1
Autor:
Patrick Wen, Caroline Duault, Edgar Gonzalez-Kozlova, Kevin Brennan, Tyson Holmes, Seunghee Kim-Schulze, Kai Nie, Kimberly Argueta, Jacques Fehr, Mina Pichavant, Diane Del Valle, Andrew Gentles, Sacha Gnjatic, Holden Maecker, Xiaobu Ye, David Reardon, Wenya Linda Bi, Pierpaolo Peruzzi, Nirav Patel, Roy Strowd, Stephen Tatter, Ian Lee, Tobias Walbert, James Snyder, Steven Brem, Arati Desai, Stephen Bagley, Nduka Amankulor, Frank Lieberman, Megan Mantica, Lenika Lopez, Susan Bell, Andrea Manzanera, Sean Lawler, Lixian Jin, Neeraja Danda, Serena Desideri, L Burt Nabors, Stuart Grossman, E Chiocca, Paul Tak, Francesca Barone
Publikováno v:
Late-Breaking Abstracts.
Autor:
Zachary Gersey, Arka Mallela, Xiaoran Zhang, Matthew Pease, Mohamed Abdelhakiem, Thomas Pearce, Frank Lieberman, Megan Mantica, Richard Phillips, Stephen Bagley, MacLean Nasrallah, Zev Binder, Steven Brem, Isaac Chen, Donald M O’Rourke, Pascal Zinn, Zaid Siddiqui, Nduka Amankulor
Publikováno v:
Neuro-Oncology. 24:vii260-vii261
OBJECTIVES Although the impact of surgery in glioblastoma (GBM) is well-established, there is insufficient data to determine how surgical resection affects overall survival (OS). The impact of other GBM genomic alterations on EOR-induced survival rem
Autor:
Eudocia Lee, Michelle Rudek, Veronica Rendo, Nicholas Khuu, Tobias Walbert, Matthias Holdhoff, Frank Lieberman, Arati Desai, Roy Strowd, Emily Lapinskas, Kristine Pelton, William Pisano, Serena Desideri, Neeraja Danda, Joy Fisher, Xiaobu Ye, L Burt Nabors, Stuart Grossman, Rameen Beroukhim, Brian Alexander, Keith Ligon, Patrick Y Wen
Publikováno v:
Neuro-Oncology. 24:vii76-vii76
BACKGROUND KRT232 is an orally bioavailable, selective small molecule inhibitor of MDM2 that blocks the protein-protein interaction between MDM2 and p53. We performed a surgical window of opportunity trial of KRT232 in patients with recurrent GBM. ME
Autor:
Oluwatosin Akintola, Jorg Dietrich, Alona Muzikansky, Melissa Gardner, Gilbert Youssef, Raymond Huang, Elizabeth Gerstner, Patrick Y Wen, Michael Parsons, Mark Gilbert, Leland Rogers, Frank Lieberman, Merideth Wendland, Vinay Puduvalli, Dennis Shrieve, Volker Stieber, Stephanie Pugh, Minesh Mehta
Publikováno v:
Neuro-Oncology. 24:vii201-vii201
BACKGROUND The clinical trial NRG/RTOG 0825 sought to determine if the addition of bevacizumab to temozolomide and radiation improves survival in patients with newly diagnosed glioblastomas. Tertiary objectives included measuring the effect of the ad
Autor:
Michal Nisnboym, Sarah Vincze, Itay Raphael, Chaim Sneiderman, Zujian Xiong, Bo Li, Kathryn Day, Joseph Latoche, Jessie Nedrow, Carolyn Anderson, Thomas Pearce, Ian Pollack, Frank Lieberman, Jan Drappatz, Wilson Edwards, Gary Kohanbash
Publikováno v:
Neuro-Oncology. 24:vii177-vii177
INTRODUCTION Glioblastoma (GBM) is the most malignant brain tumor in adults, with a dismal prognosis despite aggressive therapy. Immunotherapy is currently being evaluated as a treatment modality for recurrent GBM. MRI is not adequate for response as