Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Frank Klont"'
Autor:
Frank Klont, Marieke A.J. Hof, Fleur B. Nijdam, Daan J. Touw, Stephan J.L. Bakker, Gérard Hopfgartner, Jos G.W. Kosterink, Eelko Hak
Publikováno v:
Pharmacological Research, Vol 204, Iss , Pp 107191- (2024)
Externí odkaz:
https://doaj.org/article/aff49a3d4b9948b58c6e094a3e7a30d0
Autor:
Frank Klont, Peter Horvatovich, Russell P. Bowler, Eva van Rikxoort, Jean-Paul Charbonnier, Marcel Kwiatkowski, David A. Lynch, Stephen Humphries, Rainer Bischoff, Nick H. T. ten Hacken, Simon D. Pouwels
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background There is a strong need for biomarkers to better characterize individuals with COPD and to take into account the heterogeneity of COPD. The blood protein sRAGE has been put forward as promising biomarker for COPD in general and emp
Externí odkaz:
https://doaj.org/article/6caddc2edcc14de0adb3b7b34b2ddd3b
Autor:
Katherine A. Pratte, Jeffrey L. Curtis, Katerina Kechris, David Couper, Michael H. Cho, Edwin K. Silverman, Dawn L. DeMeo, Frank C. Sciurba, Yingze Zhang, Victor E. Ortega, Wanda K. O’Neal, Lucas A. Gillenwater, David A. Lynch, Eric A. Hoffman, John D. Newell, Alejandro P. Comellas, Peter J. Castaldi, Bruce E. Miller, Simon D. Pouwels, Nick H. T. ten Hacken, Rainer Bischoff, Frank Klont, Prescott G. Woodruff, Robert Paine, R. Graham Barr, John Hoidal, Claire M. Doerschuk, Jean-Paul Charbonnier, Ruby Sung, Nicholas Locantore, John G. Yonchuk, Sean Jacobson, Ruth Tal-singer, Debbie Merrill, Russell P. Bowler
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Soluble receptor for advanced glycation end products (sRAGE) is a proposed emphysema and airflow obstruction biomarker; however, previous publications have shown inconsistent associations and only one study has investigate the ass
Externí odkaz:
https://doaj.org/article/4e44582e7f784171ad0cc7e5e1a33440
Autor:
Frank Klont, Piotr Sosnowski, Daan Kremer, Tim J. Knobbe, Ron Bonner, Hans Blokzijl, Rinse K. Weersma, Stephan J. L. Bakker, TransplantLines Investigators, Eelko Hak, Daan J. Touw, Gérard Hopfgartner
Publikováno v:
Metabolites, Vol 12, Iss 10, p 942 (2022)
Mass spectrometry (MS) is increasingly used in clinical studies to obtain molecular evidence of chemical exposures, such as tobacco smoke, alcohol, and drugs. This evidence can help verify clinical data retrieved through anamnesis or questionnaires a
Externí odkaz:
https://doaj.org/article/3f5608681d6046e8bc7992c60ab9947e
Autor:
Frank Klont, Lyanne M. Kieneker, Antonio W. Gomes-Neto, Suzanne P. Stam, Nick H. T. ten Hacken, Ido P. Kema, André P. van Beek, Else van den Berg, Péter Horvatovich, Rainer Bischoff, Stephan J. L. Bakker
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 2, p 293 (2020)
Associations between insulin-like growth factor 1 (IGF1) and mortality have been reported to be female specific in mice and in human nonagenarians. Intervention in the growth hormone (GH)-IGF1 axis may particularly benefit patients with high risk of
Externí odkaz:
https://doaj.org/article/03ed42d315a445639bea536fa014704c
Autor:
Camilo G. Sotomayor, Flavia Giubergia, Dion Groothof, Catterina Ferreccio, Ilja M. Nolte, Gerjan J. Navis, Antonio W. Gomes-Neto, Daan Kremer, Tim J. Knobbe, Michele F. Eisenga, Ramón Rodrigo, Daan J. Touw, Stephan J.L. Bakker, Kevin Damman, Vincent E. de Meijer, Robert J. Porte, Marieke T. de Boer, Henri G.D. Leuvenink, Robert A. Pol, Coby Annema, Adelita V. Ranchor, Marion J. Siebelink, Willem S. Lexmond, Bouke G. Hepkema, L. Joost van Pelt, C. Tji Gan, Erik A.M. Verschuuren, Frank A.J.A. Bodewes, Gerard Dijkstra, Hans J. Blokzijl, Bert H.G.M. Niesters, Jan-Stephan F. Sanders, Heleen Grootjans, Rianne M. Douwes, António W. Gomes-Neto, Riemer H.J.A. Slart, Michiel E. Erasmus, Coretta van Leer-Buter, Marco van Londen, Wim Timens, Arjan Diepstra, Marius C. van den Heuvel, Joëlle C. Schutten, Cas Swarte, Rinse K. Weersma, Rebecca Heiner-Fokkema, Michel Vos, Frank Klont, Eelko Hak
Publikováno v:
American Journal of Kidney Diseases, 80(1), 87-97.e1. W B SAUNDERS CO-ELSEVIER INC
RATIONALE & OBJECTIVE: Heavy metals are known to induce kidney damage and recent studies have linked minor exposures to cadmium and arsenic with increased risk of kidney allograft failure, yet the potential association of lead (Pb) with late graft fa
Autor:
Tim J. Knobbe, Daan Kremer, Rianne M. Douwes, Michele F. Eisenga, António W. Gomes-Neto, Coby Annema, J. Casper Swarte, Frank Klont, Gerjan Navis, Stefan P. Berger, Stephan J.L. Bakker, Hans Blokzijl, Frank A.J.A. Bodewes, Marieke T. de Boer, Kevin Damman, Martin H. de Borst, Arjan Diepstra, Gerard Dijkstra, Caecilia S.E. Doorenbos, Michiel E. Erasmus, C. Tji Gan, Eelko Hak, Bouke G. Hepkema, Henri G.D. Leuvenink, Willem S. Lexmond, Vincent E. de Meijer, Hubert G.M. Niesters, L. Joost van Pelt, Robert A. Pol, Robert J. Porte, Adelta V. Ranchor, Jan Stephan F. Sanders, Marion J. Siebelink, Riemer J.H.J.A. Slart, Daan J. Touw, Marius C. van den Heuvel, Coretta van Leer-Buter, Marco van Londen, Erik A.M. Verschuuren, Michel J. Vos, Rinse K. Weersma
Publikováno v:
American Journal of Kidney Diseases. W B SAUNDERS CO-ELSEVIER INC
Rationale & Objective: Prior studies report that the use of proton pump inhibitors (PPIs) can adversely affect gut microbiota and gastrointestinal uptake of micronutrients, in particular iron and magnesium, and are used frequently by kidney transplan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77014da3d3a622051eed15463b9c4a6d
https://research.rug.nl/en/publications/d89324df-914b-4f8e-bb75-9970f822fd79
https://research.rug.nl/en/publications/d89324df-914b-4f8e-bb75-9970f822fd79
Autor:
Sara Sokooti, Frank Klont, Sok Cin Tye, Daan Kremer, Rianne M Douwes, Gérard Hopfgartner, Robin P F Dullaart, Hiddo J L Heerspink, Stephan J L Bakker
Publikováno v:
Nephrology Dialysis Transplantation, 37(7), 1375-1383. Oxford University Press
Nephrology Dialysis Transplantation
Nephrology Dialysis Transplantation
Background Post-transplantation diabetes mellitus (PTDM) is a major clinical problem in kidney transplant recipients (KTRs). Diuretic-induced hyperglycaemia and diabetes have been described in the general population. We aimed to investigate whether d
Autor:
Frank Klont, Stepan Stepanović, Daan Kremer, Ron Bonner, Daan J. Touw, Eelko Hak, Stephan J.L. Bakker, Gérard Hopfgartner
Publikováno v:
Food and chemical toxicology, 165:113188. PERGAMON-ELSEVIER SCIENCE LTD
Humans are exposed to numerous chemicals daily, for example through nutrition, therapies, and lifestyle choices, which may exert beneficial or toxicological responses. In cohort studies, exposures are frequently assessed using questionnaires, althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbf3d03271ca807b0786278ba4ecd928
https://research.rug.nl/en/publications/1c70dee1-f512-4cd6-809b-f01195e67198
https://research.rug.nl/en/publications/1c70dee1-f512-4cd6-809b-f01195e67198
Publikováno v:
Analytical chemistry, Vol. 93, No 17 (2021) pp. 6638-6645
Modifiers provide fast and reliable tuning of separation in differential mobility spectrometry (DMS). DMS selectivity for separating isomeric molecules depends on the clustering modifier concentration, which is typically 1.5–3 mol % ratio of isopro