Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Frank Kalthoff"'
Autor:
Ahmad Jalili, Kirsten D Mertz, Julia Romanov, Christine Wagner, Frank Kalthoff, Anton Stuetz, Gaurav Pathria, Melanie Gschaider, Georg Stingl, Stephan N Wagner
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69064 (2013)
Melanoma is one of the most aggressive cancers and its incidence is increasing worldwide. So far there are no curable therapies especially after metastasis. Due to frequent mutations in members of the mitogen-activated protein kinase (MAPK) signaling
Externí odkaz:
https://doaj.org/article/9c2af3532f6f4c2db3d5beaf636d21d8
Autor:
Ahmad Jalili, Kirsten D. Mertz, Julia Romanov, Christine Wagner, Frank Kalthoff, Anton Stuetz, Gaurav Pathria, Melanie Gschaider, Georg Stingl, Stephan N. Wagner
Publikováno v:
PLoS ONE, Vol 8, Iss 9 (2013)
Externí odkaz:
https://doaj.org/article/0de567f441f44ff6a4e5b3c0d1e53cb4
Autor:
Brian Cox, David C. Budd, Anna King, Gareth Williams, Nicholas Duggan, Rowan Stringer, Marcus Furegati, Alfred Schmidt, Josef G. Meingassner, Kamlesh Bala, Brian Everatt, Katharine L. Turner, Jennifer Simmons, Cerys Docx, Catherine Leblanc, Gerald Dubois, Frank Kalthoff, Caroline Wilson, Lucy Barker, Karen England, Nicola Arnold, John Westwick, Edward Charles Hall, Bindi Sohal, Jennifer Willis, Heinrich Aschauer, David Andrew Sandham, Rachael Profit, Zarin Brown, Lyndon Nigel Brown, Simon J. Watson, Jodie Manini, Christoph Walker, Matthew Thomas
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:6582-6591
Optimization of a 7-azaindole-3-acetic acid CRTh2 receptor antagonist chemotype derived from high throughput screening furnished a highly selective compound NVP-QAV680 with low nM functional potency for inhibition of CRTh2 driven human eosinophil and
Autor:
Ivan J. D. Lindley, Franz Kricek, Tamás Schweighoffer, Elisabeth Priller, Frank Kalthoff, Philipp Graf, Sandra Kettner
Publikováno v:
Molecular and Cellular Biology. 27:7718-7726
The activation of dendritic cells is marked by changes both on their cell surfaces and in their functions. We define EWI-2/CD316 as an early activation marker of dendritic cells upregulated by Toll-like receptor ligands clearly before CD86 and CD83.
Autor:
Hermann Fahrngruber, Assadollah Bavandi, Frank Kalthoff, Josef G. Meingassner, Heinrich Aschauer, Boris M. Hartmann
Publikováno v:
Journal of Dermatological Science. 43:117-126
Summary Background As reported previously, oral administration of the calcineurin inhibitors (CNI) pimecrolimus and tacrolimus resulted in equipotent inhibition of the elicitation phase of contact hypersensitivity (CHS) in mice. The sensitization pha
Autor:
Andreas Bernreiter, Diana Mechtcheriakova, Erhard Hofer, Frank Kalthoff, Markus Düchler, Bernhard Schweighofer, Sophia Derdak, Yuri Sobanov
Publikováno v:
European Journal of Immunology. 31:3493-3503
The NK gene complex is a region on human chromosome 12 containing several families of lectin-like genes including the CD94 and NKG2 NK receptor genes. We report here that the region telomeric of CD94 contains in addition to the LOX-1 gene the novel h
Publikováno v:
Cytokine. 10:331-336
Interleukin 2 (IL-2)- and IL-4-mediated stimulation of survival and growth, reflected by the induction of bcl2 and c-myc, respectively, depends on the integrity of the membrane-proximal region (S-region) in the IL-2 receptor beta-chain (IL-2R beta) a
Autor:
Ahmad Jalili, Kirsten D. Mertz, Julia Romanov, Christine Wagner, Frank Kalthoff, Anton Stuetz, Gaurav Pathria, Melanie Gschaider, Georg Stingl, Stephan N. Wagner
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 9 (2013)
PLoS ONE, Vol 8, Iss 9 (2013)
Autor:
Shifeng Pan, Hans Skvara, Humphrey Gardner, Lesanka Mickel, Georg Stingl, Jeremy Decker, Anton Stuetz, Barbara Wolff-Winiski, Joseph Kelleher, Menno A. De Rie, Ilene Carlson, Georg Stary, Christopher Schuster, Corinne Emotte, Kristine Rose, Josef G. Meingassner, Heinrich Aschauer, Xu Wu, Frank Kalthoff, Olivier J. David, Arthur P. Bertolino, Ahmad Jalili, Ana Antunes
Publikováno v:
Journal of investigative dermatology, 131(8), 1735-1744. Nature Publishing Group
Journal of Investigative Dermatology, 131(8), 1735-1744. Nature Publishing Group
Journal of Investigative Dermatology, 131(8), 1735-1744. Nature Publishing Group
Basal cell carcinoma (BCC) is a distinctive manifestation in nevoid basal cell carcinoma syndrome (NBCCS) patients. Both inherited and acquired mutations of patched 1 (PTCH1), a tumor-suppressor gene controlling the activity of Smoothened (SMO), are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230301cccb94235e4bc01fcc4e5d2c05
https://pure.amc.nl/en/publications/topical-treatment-of-basal-cell-carcinomas-in-nevoid-basal-cell-carcinoma-syndrome-with-a-smoothened-inhibitor(a622e9bd-2790-4ace-9973-5e8ce636f637).html
https://pure.amc.nl/en/publications/topical-treatment-of-basal-cell-carcinomas-in-nevoid-basal-cell-carcinoma-syndrome-with-a-smoothened-inhibitor(a622e9bd-2790-4ace-9973-5e8ce636f637).html
Autor:
Karl Koettnitz, Frank Kalthoff
Publikováno v:
European Journal of Immunology. 23:988-991
The signaling pathway used by the murine or human interleukin-4 receptor (hIL-4R) has not been elucidated so far. As an approach to mapping the cytoplasmic regions of the hIL-4R that are essential for mediating the biological response upon IL-4 bindi