Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles

Autor: Huffman, Jennifer E, Nicolas, Jayna, Hahn, Julie, Heath, Adam S, Raffield, Laura M, Yanek, Lisa R, Brody, Jennifer A, Thibord, Florian, Almasy, Laura, Bartz, Traci M, Bielak, Lawrence F., Bowler, Russell P, Carrasquilla, Germán D, Chasman, Daniel I, Chen, Ming-Huei, Emmert, David B, Ghanbari, Mohsen, Haessle, Jeffery, Hottenga, Jouke-Jan, Kleber, Marcus E, Le, Ngoc-Quynh, Lee, Jiwon, Lewis, Joshua P, Li-Gao, Ruifang, Luan, Jian’an, Malmberg, Anni, Mangino, Massimo, Marioni, Riccardo E, Martinez-Perez, Angel, Pankratz, Nathan, Polasek, Ozren, Richmond, Anne, Rodriguez, Benjamin AT, Rotter, Jerome I, Steri, Maristella, Suchon, Pierre, Trompet, Stella, Weiss, Stefan, Zare, Marjan, Auer, Paul, Cho, Michael H, Christofidou, Paraskevi, Davies, Gail, de Geus, Eco, Deleuze, Jean-François, Delgado, Graciela E, Ekunwe, Lynette, Faraday, Nauder, Gögele, Martin, Greinacher, Andreas, He, Gao, Howard, Tom, Joshi, Peter K, Kilpeläinen, Tuomas O, Lahti, Jari, Linneberg, Allan, Naitza, Silvia, Noordam, Raymond, Paüls-Vergés, Ferran, Rich, Stephen S, Rosendaal, Frits R, Rudan, Igor, Ryan, Kathleen A, Souto, Juan Carlos, van Rooij, Frank JA, Wang, Heming, Zhao, Wei, Becker, Lewis C, Beswick, Andrew, Brown, Michael R, Cade, Brian E, Campbell, Harry, Cho, Kelly, Crapo, James D, Curran, Joanne E, de Maat, Moniek PM, Doyle, Margaret, Elliott, Paul, Floyd, James S, Fuchsberger, Christian, Grarup, Niels, Guo, Xiuqing, Harris, Sarah E, Hou, Lifang, Kolcic, Ivana, Kooperberg, Charles, Menni, Cristina, Nauck, Matthias, O’Connell, Jeffrey R, Orrù, Valeria, Psaty, Bruce M, Räikkönen, Katri, Smith, Jennifer A, Soria, Jose Manuel, Stott, David J, van Hylckama Vlieg, Astrid, Watkins, Hugh, Willemsen, Gonneke, Wilson, Peter, Ben-Shlomo, Yoav, Blangero, John, Boomsma, Dorret, Cox, Simon R, Dehghan, Abbas, Eriksson, Johan G, Fiorillo, Edoardo, Fornage, Myriam, Hansen, Torben, Hayward, Caroline, Ikram, M. Arfan, Jukema, J Wouter, Kardia, Sharon LR, Lange, Leslie A, März, Winfried, Mathias, Rasika A, Mitchell, Braxton D, Mook-Kanamori, Dennis O, Morange, Pierre-Emmanuel, Pedersen, Oluf, Pramstaller, Peter P, Redline, Susan, Reiner, Alexander, Ridker, Paul M, Silverman, Edwin K, Spector, Tim D, Völker, Uwe, Wareham, Nick, Wilson, James F, Yao, Jie, Trégouët, David-Alexandre, Johnson, Andrew D, Wolberg, Alisa S, de Vries, Paul S, Sabater-Lleal, Maria, Morrison, Alanna C, Smith, Nicholas L

Publikováno v: medRxiv

Genetic studies have identified numerous regions associated with plasma fibrinogen levels in Europeans, yet missing heritability and limited inclusion of non-Europeans necessitates further studies with improved power and sensitivity. Compared with ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3756e31dfd6b839e3397f5de3ba1ddff
https://europepmc.org/articles/PMC10312878/

Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: a meta-analysis of 50,345 Caucasians

Autor: Fretts, Amanda M ^*, Follis, Jack L, Nettleton, Jennifer A, Lemaitre, Rozenn N, Ngwa, Julius S, Wojczynski, Mary K, Kalafati, Ioanna Panagiota, Varga, Tibor V, Frazier-Wood, Alexis C, Houston, Denise K, Lahti, Jari, Ericson, Ulrika, van den Hooven, Edith H, Mikkilä, Vera, Kiefte-de Jong, Jessica C, Mozaffarian, Dariush, Rice, Kenneth, Renström, Frida, North, Kari E, McKeown, Nicola M, Feitosa, Mary F, Kanoni, Stavroula, Smith, Caren E, Garcia, Melissa E, Tiainen, Anna-Maija, Sonestedt, Emily, Manichaikul, Ani, van Rooij, Frank JA, Dimitriou, Maria, Raitakari, Olli, Pankow, James S, Djoussé, Luc, Province, Michael A, Hu, Frank B, Lai, Chao-Qiang, Keller, Margaux F, Perälä, Mia-Maria, Rotter, Jerome I, Hofman, Albert, Graff, Misa, Kähönen, Mika, Mukamal, Kenneth, Johansson, Ingegerd, Ordovas, Jose M, Liu, Yongmei, Männistö, Satu, Uitterlinden, André G, Deloukas, Panos, Seppälä, Ilkka, Psaty, Bruce M, Cupples, L Adrienne, Borecki, Ingrid B, Franks, Paul W, Arnett, Donna K, Nalls, Mike A, Eriksson, Johan G, Orho-Melander, Marju, Franco, Oscar H, Lehtimäki, Terho, Dedoussis, George V, Meigs, James B, Siscovick, David S

Publikováno v: In The American Journal of Clinical Nutrition November 2015 102(5):1266-1278

Infection prevention and control of highly infectious pathogens in resource-limited countries: an experience from Marburg viral disease outbreak in Kagera Region - Tanzania

Autor: Erick Kinyenje, Joseph Hokororo, Ruth Ngowi, Michael Kiremeji, Elice Mnunga, Angela Samwel, Erasto Sylvanus, Emmanuel Mnken, Missana Yango, Mikidadi Mtalika, Vida Mmbaga, Noel Saitoti, Alex Malecha, Faith Kundy, Martin Rwabilimbo, Issessanda Kaniki, Godwin Mwisomba, Erica Charles, Patrick Mughanga, Mary Kitambi, Radenta Paul, Erick Richard, Atuganile Musyani, Irene Rabiel, Gift Haule, Laura Marandu, Emmanuel Mwakapasa, Gerald Manasseh, Calvin Sindato, Medard Beyanga, Eliakimu Kapyolo, Frank Jacob, Jonathan Mcharo, Mary Mayige, Faraja Msemwa, Grace Saguti, George Kauki, Janeth Masuma, George Mrema, Mugendi Kohi, Zabulon Yoti, Michael Habtu, William Mwengee, Kokuhabwa Mukurasi, Wangeci Gatei, Paschal Ruggajo, Elias Kwesi, Eliudi Eliakimu, Pius Horumpende, Grace Magembe, Tumaini Nagu

Publikováno v: BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-10 (2024)

Abstract Marburg viral disease (MVD) is a highly infectious disease with a case fatality rate of up to 90%, particularly impacting resource-limited countries where implementing Infection Prevention and Control (IPC) measures is challenging. This pape

Externí odkaz: https://doaj.org/article/b3d78e0d68d04da5accef01e3a696d05

Dietary amino acids and the risk of hypertension in a Dutch older population: the Rotterdam Study

Autor: Altorf-van der Kuil, Wieke, Engberink, Marielle F, De Neve, Melissa, van Rooij, Frank JA, Hofman, Albert, van’t Veer, Pieter, Witteman, Jacqueline CM, Franco, Oscar H, Geleijnse, Johanna M

Publikováno v: In The American Journal of Clinical Nutrition February 2013 97(2):403-410

Prevalence and Significance of AGR2 Expression in Human Cancer

Autor: Nina Schraps, Jacob Constantin Port, Anne Menz, Florian Viehweger, Seyma Büyücek, David Dum, Ria Schlichter, Andrea Hinsch, Christoph Fraune, Christian Bernreuther, Martina Kluth, Claudia Hube‐Magg, Katharina Möller, Viktor Reiswich, Andreas M. Luebke, Patrick Lebok, Sören Weidemann, Guido Sauter, Maximilian Lennartz, Frank Jacobsen, Till S. Clauditz, Andreas H. Marx, Ronald Simon, Stefan Steurer, Baris Mercanoglu, Nathaniel Melling, Thilo Hackert, Eike Burandt, Natalia Gorbokon, Sarah Minner, Till Krech, Florian Lutz

Publikováno v: Cancer Medicine, Vol 13, Iss 21, Pp n/a-n/a (2024)

ABSTRACT Backround Anterior gradient 2 (AGR2) is a resident endoplasmic reticulum (ER) protein with a vital role in embryonal development, mucus maturation, tissue regeneration, and wound healing. Methods To determine the prevalence and clinical sign

Externí odkaz: https://doaj.org/article/63147fc510d546f48524d9789dc18496