Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Frank J. S. Lee"'
Autor:
Ping Su, Shuxin Yan, Jian Yang, Junchao Tong, James Samsom, Fan You, Yun Li, Qiuyue Chen, Anlong Jiang, Dongxu Zhai, Jiahao Chen, Zuoli Sun, Jingjing Zhou, Min Liu, Frank J. S. Lee, Zhi-Qing David Xu, Xin Wang, Neil Vasdev, Albert H. C. Wong, Fang Liu
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
Serum amyloid P component (SAP) is a universal constituent of human amyloid deposits including those in Alzheimer's disease. SAP has been observed to be elevated in patients with depression, and higher SAP levels are associated with better response t
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136641 (2015)
The regulation of the dopamine transporter (DAT) impacts extracellular dopamine levels after release from dopaminergic neurons. Furthermore, a variety of protein partners have been identified that can interact with and modulate DAT function. In this
Externí odkaz:
https://doaj.org/article/7c424bfee7cd438eb8aef9b8cc6adbee
Publikováno v:
Synapse (New York, N.Y.). 71(5)
Using an in vitro model of ischemic stroke we treated differentiated SH-SY5Y cells to oxygen-glucose deprivation (OGD) followed by a reperfusion period where normal growth conditions were restored. Cells undergoing OGD exhibited significant cell deat
Publikováno v:
Nature Medicine. 8:600-606
The mechanism by which dopaminergic neurons are selectively lost in Parkinson disease (PD) is unknown. Here we show that accumulation of alpha-synuclein in cultured human dopaminergic neurons results in apoptosis that requires endogenous dopamine pro
Publikováno v:
The FASEB Journal. 15:916-926
Publikováno v:
Molecules and cells. 25(2)
Dopamine is a major neurotransmitter in the mammalian central nervous system (CNS) that regulates neuroendocrine functions, locomotor activity, cognition and emotion. The dopamine system has been extensively studied because dysfunction of this system