Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Frank J Wolters"'
Autor:
Marije J Splinter, Premysl Velek, M Kamran Ikram, Brenda C T Kieboom, Robin P Peeters, Patrick J E Bindels, M Arfan Ikram, Frank J Wolters, Maarten J G Leening, Evelien I T de Schepper, Silvan Licher
Publikováno v:
PLoS Medicine, Vol 18, Iss 11, p e1003854 (2021)
BackgroundDuring the Coronavirus Disease 2019 (COVID-19) pandemic, the number of consultations and diagnoses in primary care and referrals to specialist care declined substantially compared to prepandemic levels. Beyond deferral of elective non-COVID
Externí odkaz:
https://doaj.org/article/6e49e3b151544a469d4f21b9cf20bb5a
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0253698 (2021)
IntroductionNeutrophil extracellular traps (NETs) are DNA scaffolds enriched with antimicrobial proteins. NETs have been implicated in the development of various diseases, such as cardiovascular disease. Here, we investigate the association of demogr
Externí odkaz:
https://doaj.org/article/02c4014de52445fc8f830c84e4e0210b
Autor:
Yuan Ma, Frank J Wolters, Lori B Chibnik, Silvan Licher, M Arfan Ikram, Albert Hofman, M Kamran Ikram
Publikováno v:
PLoS Medicine, Vol 16, Iss 11, p e1002933 (2019)
BackgroundVariation in blood pressure may relate to dementia risk via autonomic disturbance or hemodynamic mechanisms, but the long-term associations are unclear. We aimed to determine whether blood pressure variation over a period of years, consider
Externí odkaz:
https://doaj.org/article/6e6f8aaca8bc489ba6f543f2a96d86ff
Autor:
Frank J Wolters, Qiong Yang, Mary L Biggs, Johanna Jakobsdottir, Shuo Li, Daniel S Evans, Joshua C Bis, Tamara B Harris, Ramachandran S Vasan, Nuno R Zilhao, Mohsen Ghanbari, M Arfan Ikram, Lenore Launer, Bruce M Psaty, Gregory J Tranah, Alexander M Kulminski, Vilmundur Gudnason, Sudha Seshadri, E2-CHARGE investigators
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219668 (2019)
BackgroundApolipoprotein E is a glycoprotein best known as a mediator and regulator of lipid transport and uptake. The APOE-ε4 allele has long been associated with increased risks of Alzheimer's disease and mortality, but the effect of the less prev
Externí odkaz:
https://doaj.org/article/e8df3337ad3c4799b05b9e808e6c6f26
Autor:
Jing Qian, Frank J Wolters, Alexa Beiser, Mary Haan, M Arfan Ikram, Jason Karlawish, Jessica B Langbaum, John M Neuhaus, Eric M Reiman, J Scott Roberts, Sudha Seshadri, Pierre N Tariot, Beth McCarty Woods, Rebecca A Betensky, Deborah Blacker
Publikováno v:
PLoS Medicine, Vol 14, Iss 3, p e1002254 (2017)
BACKGROUND:With the onset of prevention trials for individuals at high risk for Alzheimer disease, there is increasing need for accurate risk prediction to inform study design and enrollment, but available risk estimates are limited. We developed ris
Externí odkaz:
https://doaj.org/article/b710f4a52ee946588e0dce05432650b4
Autor:
Ilse vom Hofe, Bruno H. Stricker, Meike W. Vernooij, M. Kamran Ikram, M. Arfan Ikram, Frank J. Wolters
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Benzodiazepine use is common, particularly in older adults. Benzodiazepines have well-established acute adverse effects on cognition, but long-term effects on neurodegeneration and dementia risk remain uncertain. Methods We includ
Externí odkaz:
https://doaj.org/article/3e425f59612e433990f8ac8341df49a8
Autor:
Frank J Wolters, Francesco U S Mattace-Raso, Peter J Koudstaal, Albert Hofman, M Arfan Ikram, Heart Brain Connection Collaborative Research Group
Publikováno v:
PLoS Medicine, Vol 13, Iss 10, p e1002143 (2016)
Orthostatic hypotension (OH) is a common cause of transient cerebral hypoperfusion in the population. Cerebral hypoperfusion is widely implicated in cognitive impairment, but whether OH contributes to cognitive decline and dementia is uncertain. We a
Externí odkaz:
https://doaj.org/article/710730580b844edbae0bdd89a7d2ad97
Autor:
Magdalena Beran, Willemijn J. Jansen, Julie E. Oomens, Justine E.F. Moonen, Pieter Jelle Visser, Martijn A. Huisman, Almar A.L. Kok, Astrid C.J. Nooyens, W.M. Monique Verschuren, Coen D.A. Stehouwer, Casper Schalkwijk, Sebastian Köhler, Martin van Boxtel, Marian Beekman, P. Eline Slagboom, Frank J. Wolters, M. Arfan Ikram, Costanza L. Vallerga, Joyce B.J. van Meurs, Mohsen Ghanbari, Jet M.J. Vonk, Mirjam I. Geerlings, Thomas T. van Sloten, Miranda T. Schram
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100271- (2024)
Introduction: Endothelial dysfunction has various detrimental effects on the brain that may lead to cognitive decline. However, data on the direct association between endothelial dysfunction and cognitive performance in humans are scarce. The aim of
Externí odkaz:
https://doaj.org/article/011366f97831404883e57f2adebe9ee8
Autor:
Mirthe Coenen, Geert Jan Biessels, Charles DeCarli, Evan F. Fletcher, Pauline M. Maillard, Frederik Barkhof, Josephine Barnes, Thomas Benke, Jooske M.F. Boomsma, Christopher P.L.H. Chen, Peter Dal-Bianco, Anna Dewenter, Marco Duering, Christian Enzinger, Michael Ewers, Lieza G. Exalto, Nicolai Franzmeier, Onno Groeneveld, Saima Hilal, Edith Hofer, Huiberdina L. Koek, Andrea B. Maier, Cheryl R. McCreary, Janne M. Papma, Ross W. Paterson, Yolande A.L. Pijnenburg, Anna Rubinski, Reinhold Schmidt, Jonathan M. Schott, Catherine F. Slattery, Eric E. Smith, Carole H. Sudre, Rebecca M.E. Steketee, Esther van den Berg, Wiesje M. van der Flier, Narayanaswamy Venketasubramanian, Meike W. Vernooij, Frank J. Wolters, Xu Xin, J. Matthijs Biesbroek, Hugo J. Kuijf
Publikováno v:
NeuroImage: Clinical, Vol 40, Iss , Pp 103547- (2023)
Introduction: The spatial distribution of white matter hyperintensities (WMH) on MRI is often considered in the diagnostic evaluation of patients with cognitive problems. In some patients, clinicians may classify WMH patterns as “unusual”, but th
Externí odkaz:
https://doaj.org/article/5540ab7b51b04a4e98f8f59244635cc5
Autor:
Fang Zhu, Frank J. Wolters, Amber Yaqub, Maarten J.G. Leening, Mohsen Ghanbari, Eric Boersma, M. Arfan Ikram, Maryam Kavousi
Publikováno v:
JACC: Heart Failure, 11(1), 93-102. Elsevier
Background: Amyloid-β (Aβ) may be related to cardiac function. However, there are limited data on the association of plasma Aβ with cardiac function and risk of heart failure (HF) in the general population. Objectives: This study sought to determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ebf691042371fbd7528d4998856a17
https://doi.org/10.1016/j.jchf.2022.09.006
https://doi.org/10.1016/j.jchf.2022.09.006