Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Frank J Secreto"'
Autor:
Jodi Scholz, Frank J. Secreto, Joan Wobig, Joe Kurian, Clint Hagen, Alexandra Zinnen, Don Vu, Steven J. Johnson, Frank Cetta, Yasir Qureshi, Rachel Reams, Bryan Cannon, Christina M. Heyer, Minhwang Chang, Numrah Fadra, Jennifer Coonen, Heather A. Simmons, Andres Mejia, Jennifer M. Hayes, Puja Basu, Saverio Capuano, Viktoriya Bondarenko, Jeanette M. Metzger, Timothy J. Nelson, Marina E. Emborg
Publikováno v:
Cell Transplantation, Vol 33 (2024)
Cardiac ventricular pressure overload affects patients with congenital heart defects and can cause cardiac insufficiency. Grafts of stem cell–derived cardiomyocytes are proposed as a complementary treatment to surgical repair of the cardiac defect,
Externí odkaz:
https://doaj.org/article/439629bc292c41d8a4faaeffc28551c6
Autor:
Zhi-Zhang Yang, Deanna M Grote, Steven C Ziesmer, Bing Xiu, Nicole R Yates, Frank J Secreto, Lucy S Hodge, Thomas E Witzig, Anne J Novak, Stephen M Ansell
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59456 (2013)
While the effect of TGF-β on malignant B cells in non-Hodgkin lymphoma (NHL) has been previously evaluated, studies to specifically define the role of TGF-β in tumor immunity in B-cell NHL are limited. We found that soluble TGF-β, secreted by both
Externí odkaz:
https://doaj.org/article/8bc3e772970d465d8e27b1058840d1e1
Autor:
David F Razidlo, Tiffany J Whitney, Michelle E Casper, Meghan E McGee-Lawrence, Bridget A Stensgard, Xiaodong Li, Frank J Secreto, Sarah K Knutson, Scott W Hiebert, Jennifer J Westendorf
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11492 (2010)
Histone deacetylase (Hdac)3 is a nuclear enzyme that contributes to epigenetic programming and is required for embryonic development. To determine the role of Hdac3 in bone formation, we crossed mice harboring loxP sites around exon 7 of Hdac3 with m
Externí odkaz:
https://doaj.org/article/782d7d2bcd6441dc8442d80bda9aaaf9
Publikováno v:
Stem Cells and Development
The functional maturation status of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) has a notable impact upon their use in pharmacological studies, disease modeling, and therapeutic applications. Non-cardiomyocytes (non-CMs) pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8301a91ff774dfafdd1932f176c983
https://doi.org/10.1089/scd.2019.0098
https://doi.org/10.1089/scd.2019.0098
Autor:
Alison Barkhymer, Frank J. Secreto, Boyd Rasmussen Timothy J. Nelson, David R. Pease, Chanakha K. Navaratnarajah, Kyle G. Howell, Jay W. Schneider, Trace A. Christensen, Yoshihiro Kawaoka, Jon E. Charlesworth, Wanek Family Program for HLHS-Stem Cell Pipeline, Biruhalem Taye, Roberto Cattaneo, Peter Halfmann
Severe cardiovascular complications can occur in coronavirus disease of 2019 (COVID-19) patients. Cardiac damage is attributed mostly to a bystander effect: the aberrant host response to acute respiratory infection. However, direct infection of cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6272bfb68d5c3040a37c85ade3f35e2f
https://doi.org/10.1101/2021.07.30.454437
https://doi.org/10.1101/2021.07.30.454437
Autor:
Timothy J. Nelson, Frank J. Secreto, Alyson J. Smith, Bonnie K. Arendt, Sybil C. L. Hrstka, Ester Perales-Clemente, Emma B. Brandt, Elizabeth S. Bruinsma, Xing Li, Gresin Hawse, Saji Oommen, Dennis A. Wigle
Publikováno v:
Stem Cells Translational Medicine
Human induced pluripotent stem cells (hiPSC) hold great promise in diagnostic and therapeutic applications. However, translation of hiPSC technology depends upon a means of assessing hiPSC quality that is quantitative, high-throughput, and can deciph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d8d1987156c9fa8e03ceea4491f669
http://europepmc.org/articles/PMC6430057
http://europepmc.org/articles/PMC6430057
Autor:
Muzaffer Cicek, Kevin S. Pitel, Nalini M. Rajamannan, Molly Nelson Holte, Sarah G. Withers, K. Venuprasad, John R. Hawse, Elizabeth S. Bruinsma, Frank J. Secreto, Malayannan Subramaniam
Publikováno v:
Nucleic Acids Research
We have previously demonstrated that TGFβ Inducible Early Gene-1 (TIEG1), also known as KLF10, plays important roles in mediating skeletal development and homeostasis in mice. TIEG1 has also been identified in clinical studies as one of a handful of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8fe24e1aba38de8e596d4f6b14ac16
https://doi.org/10.1093/nar/gkx118
https://doi.org/10.1093/nar/gkx118
Publikováno v:
Advances in experimental medicine and biology. 1212
Induced pluripotent stem cells (iPSCs) offer great promise in the areas of disease modeling, basic research, drug development, and regenerative medicine. Much of their value comes from the fact that they can be used to create otherwise inaccessible c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06aee468566176edc2e0d3d74251b328
https://pubmed.ncbi.nlm.nih.gov/30850960
https://pubmed.ncbi.nlm.nih.gov/30850960
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030328221
Induced pluripotent stem cells (iPSCs) offer great promise in the areas of disease modeling, basic research, drug development, and regenerative medicine. Much of their value comes from the fact that they can be used to create otherwise inaccessible c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b335b268f7b485a2b398fc6c4067fa0a
https://doi.org/10.1007/5584_2019_350
https://doi.org/10.1007/5584_2019_350
Autor:
Andre Terzic, Timothy J. Nelson, Timothy M. Olson, Frank J. Secreto, Rosanna Beraldi, Almudena Martinez Fernandez, Xing Li, Santiago Reyes
Publikováno v:
Human Molecular Genetics. 23:3779-3791
Dilated cardiomyopathy (DCM) due to mutations in RBM20, a gene encoding an RNA-binding protein, is associated with high familial penetrance, risk of progressive heart failure and sudden death. Although genetic investigations and physiological models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff7e0943d518f2778be3807cc4554d3
https://doi.org/10.1093/hmg/ddu091
https://doi.org/10.1093/hmg/ddu091