Zobrazeno 1 - 10
of 220
pro vyhledávání: '"Frank J Accurso"'
Autor:
Jessica E Pittman, Hannah Noah, Hollin E Calloway, Stephanie D Davis, Margaret W Leigh, Mitchell Drumm, Scott D Sagel, Frank J Accurso, Michael R Knowles, Marci K Sontag
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177215 (2017)
Pseudomonas aeruginosa has been suggested as a major determinant of poor pulmonary outcomes in cystic fibrosis (CF), although other factors play a role. Our objective was to investigate the association of early childhood Pseudomonas infection on diff
Externí odkaz:
https://doaj.org/article/0fb2327c92db43f1927139cc46740a49
Autor:
Emily J Johnson, Edith T Zemanick, Frank J Accurso, Brandie D Wagner, Charles E Robertson, J Kirk Harris
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147643 (2016)
BACKGROUND:Staphylococcus aureus is a common and significant pathogen in cystic fibrosis. We sought to determine if quantitative PCR (qPCR) and 16S rRNA gene sequencing could provide a rapid, culture-independent approach to the identification of S. a
Externí odkaz:
https://doaj.org/article/25cc8f6b4dba4fb3b7bbc0fe355857e0
Autor:
Edith T Zemanick, J Kirk Harris, Brandie D Wagner, Charles E Robertson, Scott D Sagel, Mark J Stevens, Frank J Accurso, Theresa A Laguna
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62917 (2013)
Pulmonary exacerbations (PEx), frequently associated with airway infection and inflammation, are the leading cause of morbidity in cystic fibrosis (CF). Molecular microbiologic approaches detect complex microbiota from CF airway samples taken during
Externí odkaz:
https://doaj.org/article/104336e4078546e084d8ed636e9ba635
Autor:
Steven M Rowe, Bo Liu, Aubrey Hill, Heather Hathorne, Morty Cohen, John R Beamer, Frank J Accurso, Qunming Dong, Claudia L Ordoñez, Anne J Stone, Eric R Olson, John P Clancy, VX06-770-101 Study Group
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e66955 (2013)
Nasal potential difference (NPD) is used as a biomarker of the cystic fibrosis transmembrane conductance regulator (CFTR) and epithelial sodium channel (ENaC) activity. We evaluated methods to detect changes in chloride and sodium transport by NPD ba
Externí odkaz:
https://doaj.org/article/0a91e14016b6404f889b4e85926f8847
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80235 (2013)
Although many predictors have been evaluated, a set of strong independent prognostic mortality indicators has not been established in children with pediatric pulmonary arterial hypertension (PAH). The aim of this study was to identify a combination o
Externí odkaz:
https://doaj.org/article/0f20365f9cf8498a979309823cb33279
Autor:
Edith T Zemanick, Brandie D Wagner, Scott D Sagel, Mark J Stevens, Frank J Accurso, J Kirk Harris
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15101 (2010)
The cystic fibrosis (CF) airway microbiome is complex; polymicrobial infections are common, and the presence of fastidious bacteria including anaerobes make culture-based diagnosis challenging. Quantitative real-time PCR (qPCR) offers a culture-indep
Externí odkaz:
https://doaj.org/article/beb5211ec1c44314b6c8894daa83636c
Autor:
Mark Duncan, Brandie D. Wagner, Keri Murray, Jenna Allen, Kelley Colvin, Frank J. Accurso, D. Dunbar Ivy
Publikováno v:
Mediators of Inflammation, Vol 2012 (2012)
Background. Management of pediatric pulmonary hypertension (PH) remains challenging. We have assessed a panel of circulating proteins in children with PH to investigate their value as predictive and/or prognostic biomarkers. From these determinations
Externí odkaz:
https://doaj.org/article/7b247da16bf24af4aaf51dc13d161ebc
Autor:
Nicole Mayer-Hamblett, George Retsch-Bogart, Margaret Kloster, Frank Accurso, Margaret Rosenfeld, Gary Albers, Philip Black, Perry Brown, AnneMarie Cairns, Stephanie D. Davis, Gavin R. Graff, Gwendolyn S. Kerby, David Orenstein, Rachael Buckingham, Bonnie W. Ramsey, Frank J. Accurso, Michelle Howenstine, Susan Jacob, Richard Kronmal, Robert Kuhn, Karen McCoy, David Nichols, Scott Sagel, Lisa Saiman, John Sheridan, Benjamin Wilfond, Edith Zemanick, Irene Bondick, Lauren Braam, Margaret Brassil, Missy Cianciola, Sonya Heltshe, Miya Johnson, Jean Kirihara, Ada Kong, Shelly Ma, Sharon McNamara, Lindsey Mann, Kelly Moormann, Matthew Myers, Kathy Seidel, Michelle Skalland, Carmen Ufret-Vincenty, Jill VanDalfsen, Christopher H. Goss, David J. Horne, Erin K. Kross, Peter J. Leary, Kathleen J. Ramos, Patricia Roush, Jack C. Salerno, Gregory Omlor, Deborah Ouellette, Deanna Green, Kathy Hosler, Adrienne Savant, Zainub Ashrafi, Ariel Berlinski, Andrea Ross, Gregory Sawicki, Robert Fowler, Monica Ulles, Freda Branch, Kevin Kirchner, Kerry DiBenardo, Gwendolyn Kerby, Meg Anthony, Thomas Keens, Alejandra Franquez, Carmen Reyes, Ibrahim Abdulhamid, Catherine Van Wagnen, Elizabeth Hartigan, Carley Mihlo, Ronald Williams, Margaret Lessard, Laura Sass, Erin McAndrews, Jennifer Parrott, Julie Noe, Patricia Hastings, Theresa Kump, John Clancy, Stacey Niehaus, Juyan Zhou, Gary Mueller, Sandy Bartosik, Jason Fullmer, Colleen Millian, Arlene Stecenko, Joy Dangerfield, Gavin Graff, Diane Kitch, Carrie Milliard, Robert Zanni, Bridget Marra, Patsy Guittar, Melinda Smith, David Schaeffer, Elizabeth DeLuca, John Welter, Meighan Gallagher, Armando Ramirez, Alexandra Cornell, Erika Simeon, Dion Roberts, Katherine Nelson, James Chmiel, Cindy Schaefer, Lori Shively, James Wallace, Allisa Richter, Bonnie Ramsey, Jessica Pittman, Tina Hicks, Dixie Durham, Carlos Milla, Jacquelyn Zirbes, Christopher Fortner, Valoree Suttmore, Rose Thompson, Cori Daines, Monica Varela, Timothy Starner, Mary Teresi, Samya Nasr, Dawn Kruse, Heather Thomas, Lisa Houdesheldt, Carol Barlow, Rose Cunnion, Saumini Srinivasan, Catherine Horobetz, Fadi Asfour, Jessica Francis, Michael Rock, Linda Makholm, Marie Egan, Catalina Guzman
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Rationale: New isolation of Pseudomonas aeruginosa (Pa) is generally treated with inhaled antipseudomonal antibiotics such as tobramycin inhalation solution (TIS). A therapeutic approach that complements traditional antimicrobial therapy by reducing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8de38deedbb09db05717ce5b591a87
https://doi.org/10.1164/rccm.201802-0215oc
https://doi.org/10.1164/rccm.201802-0215oc
Publikováno v:
Journal of Cystic Fibrosis
Background Pulmonary exacerbations (PEx) in children with cystic fibrosis (CF) are frequently treated in the outpatient setting with oral antibiotics. However, little is known about the characteristics of PEx managed on an outpatient basis and the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d6136db2cd38d868abca771535bd70
https://doi.org/10.1016/j.jcf.2018.05.015
https://doi.org/10.1016/j.jcf.2018.05.015
Autor:
Carlos Milla, Donald R. VanDevanter, V. V. Beckett, Jane L. Burns, Nicole Mayer-Hamblett, Raksha Jain, Michael W. Konstan, James F. Chmiel, Frank J. Accurso
Publikováno v:
Journal of Cystic Fibrosis. 17:484-491
Background Chronic Pseudomonas aeruginosa ( Pa ) airways infection, exuberant local inflammation, and progressive lung function loss are hallmarks of cystic fibrosis (CF). KB001-A is an anti-PcrV PEGylated monoclonal antibody fragment to the Type III
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce6209001b798b329742817a0f3849f
https://doi.org/10.1016/j.jcf.2017.12.006
https://doi.org/10.1016/j.jcf.2017.12.006