Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Frank J, Lovicu"'
Autor:
Fatima Wazin, Frank J. Lovicu
Publikováno v:
Cells, Vol 13, Iss 4, p 290 (2024)
The development and growth of the eye depends on normal lens morphogenesis and its growth. This growth, in turn, is dependent on coordinated proliferation of the lens epithelial cells and their subsequent differentiation into fiber cells. These cellu
Externí odkaz:
https://doaj.org/article/bf9845c170624f32b00f452aba190ced
Autor:
Tayler F. L. Wishart, Frank J. Lovicu
Publikováno v:
Cells, Vol 12, Iss 10, p 1364 (2023)
Heparan sulphate proteoglycans (HSPGs) consist of a core protein decorated with sulphated HS-glycosaminoglycan (GAG) chains. These negatively charged HS-GAG chains rely on the activity of PAPSS synthesising enzymes for their sulfation, which allows t
Externí odkaz:
https://doaj.org/article/6ebe715451af4daf96645ab557fde24a
Autor:
Mary Flokis, Frank J. Lovicu
Publikováno v:
Cells, Vol 12, Iss 6, p 827 (2023)
Fibroblast growth factor (FGF) and transforming growth factor-beta (TGF-β) can regulate and/or dysregulate lens epithelial cell (LEC) behaviour, including proliferation, fibre differentiation, and epithelial–mesenchymal transition (EMT). Earlier s
Externí odkaz:
https://doaj.org/article/780db7b0a3c244aba3a84801eaf30361
Autor:
Anil Upreti, Stephanie L. Padula, Jared A. Tangeman, Brad D. Wagner, Michael J. O’Connell, Tycho J. Jaquish, Raye K. Palko, Courtney J. Mantz, Deepti Anand, Frank J. Lovicu, Salil A. Lachke, Michael L. Robinson
Publikováno v:
Cells, Vol 12, Iss 3, p 501 (2023)
Lens epithelial explants are comprised of lens epithelial cells cultured in vitro on their native basement membrane, the lens capsule. Biologists have used lens epithelial explants to study many different cellular processes including lens fiber cell
Externí odkaz:
https://doaj.org/article/614285aa20b8447d914ed706d58c4973
Autor:
Yihui Song, Morgan Overmass, Jiawen Fan, Chris Hodge, Gerard Sutton, Frank J. Lovicu, Jingjing You
Publikováno v:
Frontiers in Surgery, Vol 8 (2021)
Collagens represent a major group of structural proteins expressed in different tissues and display distinct and variable properties. Whilst collagens are non-transparent in the skin, they confer transparency in the cornea and crystalline lens of the
Externí odkaz:
https://doaj.org/article/caecc254211547349959e8d1e69ae4b8
Autor:
Daisy Y. Shu, Frank J. Lovicu
Publikováno v:
Cells, Vol 10, Iss 10, p 2604 (2021)
Bone morphogenetic proteins (BMPs) are a diverse class of growth factors that belong to the transforming growth factor-beta (TGFβ) superfamily. Although originally discovered to possess osteogenic properties, BMPs have since been identified as criti
Externí odkaz:
https://doaj.org/article/79297c7442194075b24edda167b76359
Publikováno v:
Journal of Cataract and Refractive Surgery. 48:355-362
To compare the repair of penetrating corneal incisions in an in vivo rabbit model using a laser-activated thin-film adhesive, sutures, or self-seal.The University of Sydney, Camperdown, Australia.Animal studies.Under an operating microscope, 2.0 mm p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052281c9528643a5c058d9986a273030
https://doi.org/10.1097/j.jcrs.0000000000000751
https://doi.org/10.1097/j.jcrs.0000000000000751
Autor:
Tayler F.L. Wishart, Frank J. Lovicu
Publikováno v:
Progress in Retinal and Eye Research. 93:101118
Heparan sulfate proteoglycans (HSPGs) reside in most cells; on their surface, in the pericellular milieu and/or extracellular matrix. In the eye, HSPGs can orchestrate the activity of key signalling molecules found in the ocular environment that prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41acf11e2985f2a6f22f95d58ffaa19d
https://doi.org/10.1016/j.preteyeres.2022.101118
https://doi.org/10.1016/j.preteyeres.2022.101118
Autor:
Stephanie L. Padula, Elaine P. Sidler, Frank J. Lovicu, Courtney J. Manz, Michael L. Robinson, Brad D. Wagner
Publikováno v:
Dev Biol
Fibroblast growth factor receptor (FGFR) signaling patterns multiple tissues in both vertebrates and invertebrates, largely through the activation of intracellular kinases. Recent studies have demonstrated that the phosphatase, PTEN negatively regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc73ca162c1ad85dd037f7d01d21ea7
https://doi.org/10.1016/j.ydbio.2020.07.017
https://doi.org/10.1016/j.ydbio.2020.07.017
Publikováno v:
International Journal of Radiation Biology. 96:1339-1361
Since the exact development of posterior subcapsular cataracts (PSCs) is poorly understood, we review various risk factors and propose a two-stage etiology for PSCs.The biological mechanisms associated with age-related cataracts (primarily nuclear ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5fc165e88ba6fa529e3c6f83be2c528
https://doi.org/10.1080/09553002.2020.1812759
https://doi.org/10.1080/09553002.2020.1812759