Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Frank J, Delfino"'
Autor:
Selin Somersan-Karakaya, Kenneth C. Turner, Luz Cortes-Burgos, Jutta Miller, Michael LaCroix-Fralish, Veronika Logovinsky, Yamini Patel, Richard Torres, Samit Ganguly, Aurora Breazna, Michelle DeVeaux, Rafia Bhore, Min Gao, Frank J. Delfino, Ashique Rafique, Jeanette L. Fairhurst, Charleen Hunt, Robert Babb, Ashok Badithe, William T. Poueymirou, Ronald Surowitz, Sylvie Rottey, Andrew J. Murphy, Olivier Harari, Lynn E. Macdonald, Susan D. Croll
Publikováno v:
Neurobiology of Pain, Vol 14, Iss , Pp 100136- (2023)
The artemin-GFRα3 signaling pathway has been implicated in various painful conditions including migraine, cold allodynia, hyperalgesia, inflammatory bone pain, and mouse knees contain GFRα3-immunoreactive nerve endings. We developed high affinity m
Externí odkaz:
https://doaj.org/article/c0682c375e514d369668aca491d09e17
Autor:
Andres E. Perez Bay, Devon Faulkner, John O. DaSilva, Tara M. Young, Katie Yang, Jason T. Giurleo, Dangshe Ma, Frank J. Delfino, William C. Olson, Gavin Thurston, Christopher Daly, Julian Andreev
Publikováno v:
Molecular Cancer Therapeutics. 22:357-370
Most antibody–drug conjugates (ADC) approved for the treatment of cancer contain protease-cleavable linkers. ADCs that traffic to lysosomes traverse highly acidic late endosomes, while ADCs that recycle to the plasma membrane traffic through mildly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f56815130f46f441b4715fc78b7645f3
https://doi.org/10.1158/1535-7163.mct-22-0414
https://doi.org/10.1158/1535-7163.mct-22-0414
Autor:
Julian Andreev, Christopher Daly, Gavin Thurston, William C. Olson, Frank J. Delfino, Dangshe Ma, Jason T. Giurleo, Katie Yang, Tara M. Young, John O. DaSilva, Devon Faulkner, Andres E. Perez Bay
In vivo processing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fd62f71230f806b0d64d97a9e3860a
https://doi.org/10.1158/1535-7163.22523856
https://doi.org/10.1158/1535-7163.22523856
Autor:
Christopher Daly, Gavin Thurston, John S. Rudge, Douglas MacDonald, Gang Chen, Joel H. Martin, Tammy Huang, Ergang Shi, Frank J. Delfino, Jing Shan, Terra B. Potocky, Ashique Rafique, Jeanette L. Fairhurst, Liangfen Fan, Katie Yang, Bo Luan, Carla Castanaro, Li Zhang
EGFR blocking antibodies are approved for the treatment of colorectal cancer and head and neck squamous cell carcinoma (HNSCC). Although ERBB3 signaling has been proposed to limit the effectiveness of EGFR inhibitors, the underlying molecular mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b6648e17cc46bf07df9b26c704c96c
https://doi.org/10.1158/1535-7163.c.6536475
https://doi.org/10.1158/1535-7163.c.6536475
Autor:
Christopher Daly, Gavin Thurston, John S. Rudge, Douglas MacDonald, Gang Chen, Joel H. Martin, Tammy Huang, Ergang Shi, Frank J. Delfino, Jing Shan, Terra B. Potocky, Ashique Rafique, Jeanette L. Fairhurst, Liangfen Fan, Katie Yang, Bo Luan, Carla Castanaro, Li Zhang
PDF - 78K, Effect of REGN1400 and REGN955 on ligand-induced signaling by ERBB3 and EGFR, respectively.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71092c3804bd3679a5040c51a04f7d1a
https://doi.org/10.1158/1535-7163.22500492
https://doi.org/10.1158/1535-7163.22500492
Autor:
Julian Andreev, Christopher Daly, Gavin Thurston, William C. Olson, Frank J. Delfino, Dangshe Ma, Jason T. Giurleo, Katie Yang, Tara M. Young, John O. DaSilva, Devon Faulkner, Andres E. Perez Bay
CRISPR RNA gene list
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d418d20c38e4c95b06f947cbd5f210
https://doi.org/10.1158/1535-7163.22523844
https://doi.org/10.1158/1535-7163.22523844
Autor:
Christopher Daly, Gavin Thurston, John S. Rudge, Douglas MacDonald, Gang Chen, Joel H. Martin, Tammy Huang, Ergang Shi, Frank J. Delfino, Jing Shan, Terra B. Potocky, Ashique Rafique, Jeanette L. Fairhurst, Liangfen Fan, Katie Yang, Bo Luan, Carla Castanaro, Li Zhang
PDF - 56K, Measurement of REGN1400 and REGN955 binding affinities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c1a8712c837e8c8041bfee1e5887b7
https://doi.org/10.1158/1535-7163.22500489.v1
https://doi.org/10.1158/1535-7163.22500489.v1
Autor:
Christopher Daly, Gavin Thurston, William C. Olson, Douglas MacDonald, Gang Chen, Robert Babb, Terra B. Potocky, Frank J. Delfino, Anthony Dore, Ashique Rafique, Drew Dudgeon, Matthew C. Franklin, Erica Pyles, Peter Ngoi, Julian Andreev, Andres E. Perez Bay, Katie Yang, John O. DaSilva
Supplementary figure legends and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103611ef493c27efe4af5aa0b514fa9e
https://doi.org/10.1158/1078-0432.22479116
https://doi.org/10.1158/1078-0432.22479116
Autor:
Christopher Daly, Gavin Thurston, William C. Olson, Douglas MacDonald, Gang Chen, Robert Babb, Terra B. Potocky, Frank J. Delfino, Anthony Dore, Ashique Rafique, Drew Dudgeon, Matthew C. Franklin, Erica Pyles, Peter Ngoi, Julian Andreev, Andres E. Perez Bay, Katie Yang, John O. DaSilva
Purpose:Recent clinical data demonstrate that tumors harboring MET genetic alterations (exon 14 skip mutations and/or gene amplification) respond to small-molecule tyrosine kinase inhibitors, validating MET as a therapeutic target. Although antibody-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94eb10aa84a1819835f4c6c26ab04981
https://doi.org/10.1158/1078-0432.c.6530138
https://doi.org/10.1158/1078-0432.c.6530138
Publikováno v:
Biochemical Journal. 399:141-150
The c-Fes protein tyrosine kinase is implicated in the differentiation of a number of cell types including neuronal, endothelial and myeloid cells. Structurally, Fes consists of a unique N-terminal region, followed by SH2 (Src homology domain 2) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c52d747c03aff2752dd9d6d659f0b7e
https://doi.org/10.1042/bj20060194
https://doi.org/10.1042/bj20060194