Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Frank Iverson"'
Autor:
David B. Clayson, Frank Iverson
Publikováno v:
Regulatory Toxicology and Pharmacology. 24:45-59
Mathematically based carcinogen risk assessment is based on a number of prudent default assumptions which are becoming progressively less tenable as new scientific evidence is adduced. For example, the assumptions that all rodent carcinogens will be
Publikováno v:
Annual Review of Pharmacology and Toxicology. 30:441-463
Scientific interest in forestomach carcinogenesis has been greatly heightened by the observation that butylated hydroxyanisole (BHA) is carcinogenic to rats at this site (1). BHA is one of only three synthetic phenolic antioxidants that are permitted
Autor:
Frank Iverson, Homer C. Emery
Publikováno v:
Journal of Toxicology and Environmental Health. 32:103-105
Autor:
L. Hierlihy, R. Mueller, Rekha Mehta, Eric Lok, Frank Iverson, Diane H. Bourbonnais, S. Gurofsky, Philip A. Spear
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 27(1 Pt 2)
Male and female Sprague–Dawley rats were fed diets incorporating lyophilized chinook salmon obtained from Lake Ontario and Lake Huron. After 70 days, females were bred and the progeny (F 1 ) were reared on the same fish-based diets as the adults (F
Publikováno v:
Toxicology. 89(2)
Sixty-seven female rhesus monkeys (Macaca mulatta) were orally dosed daily for 152 weeks with 0, 5, 20, 40, and 80 micrograms Aroclor 1254 (PCB)/kg body wt. Blood polychlorinated biphenyl (PCB) concentrations were highly positively correlated (r = 0.
Autor:
John F. Truelove, Frank Iverson
Publikováno v:
Natural toxins. 2(5)
Marine and terrestrial food sources are susceptible to contamination by various industrial chemicals and microbial pathogens. Both types of hazard are amenable to regulatory assessment using a single toxicology data base, along with some knowledge of
Publikováno v:
Journal of Toxicology and Environmental Health. 11:287-300
Teratogenicity of ethylenethiourea (ETU) was studied in the hamster to define the organ most vulnerable to its teratogenic action. A single intragastric dose of 600, 1200, 1800 or 2400 mg ETU/kg was given in 1.5% aqueous gelatin on d 11 of pregnancy.
Publikováno v:
Lipids. 19:704-707
Rats dosed orally for four days with 0.24 g/kg body weight per day of brominated olive oil (BOO) or brominated sesame oil (BSO) were found to accumulate dibromostearic (DBS) acid (from BOO) and DBS and tetrabromostearic (TBS) acids (from BSO) in the
Autor:
Frank. Iverson
Publikováno v:
Journal of Agricultural and Food Chemistry. 24:1238-1241
Publikováno v:
Canadian journal of physiology and pharmacology. 62(10)
Ah receptor in hepatic cytosols from adult cynomolgus monkeys (Macaca fasicularis) was identified and quantitated by its binding of the highly toxic chemical 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and the carcinogens 3-methylcholanthrene, benzo[a