Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Frank Holtrup"'
Autor:
Ari J. Rosenberg, Evgeny Izumchenko, Alexander Pearson, Zhen Gooi, Elizabeth Blair, Theodore Karrison, Aditya Juloori, Daniel Ginat, Nicole Cipriani, Mark Lingen, Hillary Sloane, Daniel L. Edelstein, Kirsten Keyser, Johannes Fredebohm, Frank Holtrup, Frederick S. Jones, Daniel Haraf, Nishant Agrawal, Everett E. Vokes
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Human papillomavirus (HPV)-associated oropharyngeal cancer (OPC) has a favorable prognosis which has led to efforts to de-intensify treatment. Response-adaptive de-escalated treatment is promising, however improved biomarkers are
Externí odkaz:
https://doaj.org/article/9a900a0e9acd46aa9f1e55c493688248
Autor:
Inga Medina Diaz, Annette Nocon, Stefanie A. E. Held, Makbule Kobilay, Dirk Skowasch, Abel J. Bronkhorst, Vida Ungerer, Johannes Fredebohm, Frank Diehl, Stefan Holdenrieder, Frank Holtrup
Publikováno v:
Diagnostics, Vol 13, Iss 7, p 1288 (2023)
Excellent pre-analytical stability is an essential precondition for reliable molecular profiling of circulating tumor DNA (ctDNA) in oncological diagnostics. Therefore, in vitro degradation of ctDNA and the additional release of contaminating genomic
Externí odkaz:
https://doaj.org/article/75a3dca641484427822aeb8e9a4e500f
Autor:
Begona Jimenez Rodriguez, Gema Diaz Córdoba, Alicia Garrido Aranda, Martina Álvarez, Luis Vicioso, Casilda Llácer Pérez, Cristina Hernando, Begoña Bermejo, Ana Julve Parreño, Ana Lluch, Matthew B. Ryder, Frederick S. Jones, Johannes Fredebohm, Frank Holtrup, María Isabel Queipo-Ortuño, Emilio Alba
Publikováno v:
Journal of Clinical Medicine, Vol 8, Iss 8, p 1183 (2019)
Circulating tumor DNA (ctDNA) has emerged as a non-invasive “liquid biopsy” for early breast cancer diagnosis. We evaluated the suitability of ctDNA analysis in the diagnosis of early breast cancer after mammography findings, comparing PIK3CA and
Externí odkaz:
https://doaj.org/article/27a8496376ef4c41a2eb61affb493ca5
Autor:
Inga Medina Diaz, Annette Nocon, Daniel H Mehnert, Johannes Fredebohm, Frank Diehl, Frank Holtrup
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166354 (2016)
Making liquid biopsy testing widely available requires a concept to ship whole blood at ambient temperatures while retaining the integrity of the cell-free DNA (cfDNA) population and stability of blood cells to prevent dilution of circulating tumor D
Externí odkaz:
https://doaj.org/article/debd5e622ecf42cdbaa969c34619b1a5
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74555 (2013)
Pancreatic cancer is one of the leading cancer-related causes of death in the western world with an urgent need for new treatment strategies. Recently, hyperforin and nemorosone have been described as promising anti-cancer lead compounds. While hyper
Externí odkaz:
https://doaj.org/article/9ab2ce2b34144810a234ad65af1e5d67
Autor:
Dominik E Dorer, Frank Holtrup, Kurt Fellenberg, Johanna K Kaufmann, Sarah Engelhardt, Jörg D Hoheisel, Dirk M Nettelbeck
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27934 (2011)
Adenoviruses (Ads), especially HAdV-5, have been genetically equipped with tumor-restricted replication potential to enable applications in oncolytic cancer therapy. Such oncolytic adenoviruses have been well tolerated in cancer patients, but their a
Externí odkaz:
https://doaj.org/article/5a1bb4a560d14376b95fac78c3fe944d
Autor:
Scott Kopetz, Stanley R. Hamilton, Hagen F. Kennecke, Paul Waring, Chris J. O'Callaghan, Christos S. Karapetis, Malcolm J. Moore, John R. Zalcberg, Timothy Price, Frank Holtrup, Hannah Quinn, Daniel L. Edelstein, Derek J. Jonker, Dongsheng Tu, Anthony Dowers, Jonathan M. Loree
Supplemental Tables and Figure Caption
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b2729e1f3b3fb50a9551f5cdff0d70
https://doi.org/10.1158/1078-0432.22478880.v1
https://doi.org/10.1158/1078-0432.22478880.v1
Autor:
Scott Kopetz, Stanley R. Hamilton, Hagen F. Kennecke, Paul Waring, Chris J. O'Callaghan, Christos S. Karapetis, Malcolm J. Moore, John R. Zalcberg, Timothy Price, Frank Holtrup, Hannah Quinn, Daniel L. Edelstein, Derek J. Jonker, Dongsheng Tu, Anthony Dowers, Jonathan M. Loree
Supplemental Figure 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082a795b700a781b2bbf2ea351e1df63
https://doi.org/10.1158/1078-0432.22478883.v1
https://doi.org/10.1158/1078-0432.22478883.v1
Autor:
Scott Kopetz, Stanley R. Hamilton, Hagen F. Kennecke, Paul Waring, Chris J. O'Callaghan, Christos S. Karapetis, Malcolm J. Moore, John R. Zalcberg, Timothy Price, Frank Holtrup, Hannah Quinn, Daniel L. Edelstein, Derek J. Jonker, Dongsheng Tu, Anthony Dowers, Jonathan M. Loree
Purpose:Expanded RAS/BRAF mutations have not been assessed as predictive for single-agent cetuximab in metastatic colorectal cancer (mCRC), and low mutant allele frequency (MAF) mutations are of unclear significance. We aimed to establish cetuximab e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3493ab03c0ff06263423b1839a575e1e
https://doi.org/10.1158/1078-0432.c.6530073.v1
https://doi.org/10.1158/1078-0432.c.6530073.v1
Autor:
Dongsheng Tu, Timothy J. Price, Hagen F. Kennecke, Daniel L. Edelstein, Scott Kopetz, Frank Holtrup, Hannah Quinn, Anthony Dowers, Stanley R. Hamilton, Derek J. Jonker, John Zalcberg, Christos S Karapetis, Paul Waring, Jonathan M. Loree, Christopher J. O'Callaghan, Malcolm J. Moore
Publikováno v:
Clinical Cancer Research. 27:52-59
Purpose: Expanded RAS/BRAF mutations have not been assessed as predictive for single-agent cetuximab in metastatic colorectal cancer (mCRC), and low mutant allele frequency (MAF) mutations are of unclear significance. We aimed to establish cetuximab